Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chris TenHoor"'
Autor:
Daniel T. Dransfield, Clive R. Wood, Maria Luisa Valentino, Shafaat A. Rabbani, Chris TenHoor, Paula Henderikx, Rene Hoet, Robert C. Ladner, Andrew E. Nixon, Sonia Schoonbroodt, Yu Lu Ma, Csaba Pazmany, Shannon Hogan, Douglas Rank, Guannan Kuang, Daniel J. Sexton, Reinoud van Gool, Annabelle Lejeune, Marc Vanhove, Qingfeng Tao, Edward Chang, Nicolas Frans, Henk Pieters, Niranjan Yanamandra, Laurent Naa, Lili Huang, Laetitia Devy
Inhibition of specific matrix metalloproteinases (MMP) is an attractive noncytotoxic approach to cancer therapy. MMP-14, a membrane-bound zinc endopeptidase, has been proposed to play a central role in tumor growth, invasion, and neovascularization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ad90f85bac4e1357eb214667eadf37f
https://doi.org/10.1158/0008-5472.c.6499896.v1
https://doi.org/10.1158/0008-5472.c.6499896.v1
Autor:
Daniel T. Dransfield, Clive R. Wood, Maria Luisa Valentino, Shafaat A. Rabbani, Chris TenHoor, Paula Henderikx, Rene Hoet, Robert C. Ladner, Andrew E. Nixon, Sonia Schoonbroodt, Yu Lu Ma, Csaba Pazmany, Shannon Hogan, Douglas Rank, Guannan Kuang, Daniel J. Sexton, Reinoud van Gool, Annabelle Lejeune, Marc Vanhove, Qingfeng Tao, Edward Chang, Nicolas Frans, Henk Pieters, Niranjan Yanamandra, Laurent Naa, Lili Huang, Laetitia Devy
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362235aff74f4e94e6209bb11bdd0a07
https://doi.org/10.1158/0008-5472.22381518.v1
https://doi.org/10.1158/0008-5472.22381518.v1
Autor:
Daniel T. Dransfield, Clive R. Wood, Maria Luisa Valentino, Shafaat A. Rabbani, Chris TenHoor, Paula Henderikx, Rene Hoet, Robert C. Ladner, Andrew E. Nixon, Sonia Schoonbroodt, Yu Lu Ma, Csaba Pazmany, Shannon Hogan, Douglas Rank, Guannan Kuang, Daniel J. Sexton, Reinoud van Gool, Annabelle Lejeune, Marc Vanhove, Qingfeng Tao, Edward Chang, Nicolas Frans, Henk Pieters, Niranjan Yanamandra, Laurent Naa, Lili Huang, Laetitia Devy
Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202e975447b6fb0d17af004056b1b698
https://doi.org/10.1158/0008-5472.22381515
https://doi.org/10.1158/0008-5472.22381515
Autor:
Jie Chen, Dina Wassaf, Malini Viswanathan, Diana Martik, Clive R. Wood, Chris TenHoor, Andrew E. Nixon, Joseph C. Biedenkapp, Daniel J. Sexton, Jennifer A. Dumont, Adam R. Mezo, Arumugam Muruganandam, Alan J. Bitonti
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology, Vol 6 (2015)
The therapeutic management of antibody mediated autoimmune disease typically involves immunosuppressant and immunomodulatory strategies. However, perturbing the fundamental role of the neonatal Fc receptor (FcRn) in salvaging IgG from lysosomal degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fdfc63ac3b5db58b466204f898d483
http://europepmc.org/articles/PMC4407741
http://europepmc.org/articles/PMC4407741
Autor:
Laurent Naa, Douglas Rank, Robert Charles Ladner, Sonia Schoonbroodt, Daniel J. Sexton, Yu Lu Ma, Guannan Kuang, Clive R. Wood, Csaba Pazmany, Henk Pieters, Marc Vanhove, Daniel T. Dransfield, Nicolas Frans, Maria-Luisa Valentino, Laetitia Devy, Lili Huang, Niranjan Yanamandra, Shafaat A. Rabbani, Andrew E. Nixon, Reinoud van Gool, Annabelle Lejeune, Qingfeng Tao, Rene Hoet, Edward F. Chang, Shannon Hogan, Chris TenHoor, Paula Henderikx
Publikováno v:
Cancer research. 69(4)
Inhibition of specific matrix metalloproteinases (MMP) is an attractive noncytotoxic approach to cancer therapy. MMP-14, a membrane-bound zinc endopeptidase, has been proposed to play a central role in tumor growth, invasion, and neovascularization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6670fac160fdffb3d278750929e86f39
https://pubmed.ncbi.nlm.nih.gov/19208838
https://pubmed.ncbi.nlm.nih.gov/19208838
Autor:
Ryan Faucette, Burt Adelman, Chris Stevens, Chris TenHoor, Jon A. Kenniston, Ryan Iarrobino, Yung Chyung, Joseph C. Biedenkapp, Leslie E. Stolz, Bradley Vince, Daniel J. Sexton
Publikováno v:
Annals of Allergy, Asthma & Immunology. 113(4):460-466.e2
Background DX-2930 is a human monoclonal antibody inhibitor of plasma kallikrein under investigation for long-term prophylaxis of hereditary angioedema. Objective To assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of DX-2930 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7b4afde8479f5bd3e962b0880d9639
Autor:
Daniel J. Sexton, Jon A. Kenniston, Yung Chyung, Chris TenHoor, Andrew E. Nixon, Ryan Faucette, Burt Adelman
Publikováno v:
Blood. 122:1066-1066
Dysregulated plasma kallikrein proteolytic activity leads to edematous attacks in hereditary angioedema (HAE) and has been associated with inflammation and thrombosis. Plasma kallikrein (pKal) is a serine protease that circulates as prekallikrein, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28037cc95d9a7ac156d8f7ca800487f4
https://doi.org/10.1182/blood.v122.21.1066.1066
https://doi.org/10.1182/blood.v122.21.1066.1066