Výsledky vyhledávání - "Chris Spurney"

Mg-Supplementation Protects Against Oxidative Stress and Cardiac Dysfunction in Chronic Highly Active Antiretroviral Therapy–Treated Rats

Autor: Jay H. Kramer, I.T. Mak, William B. Weglicki, Joanna J. Chmielinska, Chris Spurney

Highly active antiretroviral therapy (HAART) agents, azidothymidine (AZT), ritonavir (RTV), and efavirenz (EFV), were assessed in vivo for oxidative stress, cardiac injury, and dysfunction in rats, and dietary Mg-supplementation (Mg-Sup sixfold highe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f1c060c0eb8f2dc5112afa70e7c4582
https://doi.org/10.1016/b978-0-12-809853-0.00016-x

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Duchenne Muscular Dystrophy Cardiomyopathy: Early Diagnosis and Treatment

Autor: Chris Spurney, Bryan Siegel

Publikováno v: Internal Medicine Review. 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62cfd395927e0bbd101e8a051e375cfd
https://doi.org/10.18103/imr.v3i4.384

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Abstract 17186: Regional Extracellular Volume Fraction Can Identify Cardiac Muscle Changes in Patients With Duchenne Muscular Dystrophy

Autor: Laura Olivieri, Peter Kellman, Russell Cross, Kanishka Ratnayaka, Andrew E Arai, Michael S Hansen, Chris Spurney

Publikováno v: Circulation. 132

Background: Duchenne muscular dystrophy (DMD) is an X-linked inherited disorder causing dilated cardiomyopathy with variable onset and progression. Our aim was to compare native T1 mapping and extracellular volume fraction (ECV) in boys with DMD to c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6170b0bcb5ab3605e734f8462fdd0cdb
https://doi.org/10.1161/circ.132.suppl_3.17186

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Combination Antiretroviral Therapy (cART) Altered Redox/Nitrosative genes, Enhanced Systemic Stress and Cardiac dysfunction in HIV-1 Transgenic (HIV-Tg) Rats: Effects of Magnesium Supplementation (Mg-Supp)

Autor: Chris Spurney, I.T. Mak, Lama Elzohary, William B. Weglicki, Jay H. Kramer, Joanna J. Chmielinska

Publikováno v: Free Radical Biology and Medicine. 112:117

We determined if clinically used cART promoted redox/nitrosative stress and cardiac toxicity in control and HIV-Tg rats and the effects of Mg. Treatment with cART (Truvada+atazanavir/ritonavir) up to 18 weeks, induced significant hypomagnesemia (-25%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8b89424810b92cb95011fd2534f48ff
https://doi.org/10.1016/j.freeradbiomed.2017.10.175

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