Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chris S Gandhi"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33077 (2012)
Bacteria are subjected to a host of different environmental stresses. One such insult occurs when cells encounter changes in the osmolarity of the surrounding media resulting in an osmotic shock. In recent years, a great deal has been learned about m
Externí odkaz:
https://doaj.org/article/73975f9216eb44118a5dbe1c7ef72f65
Publikováno v:
Protein Science. 20:313-326
We have developed a new technique to study the oligomeric state of proteins in solution. OCAM or Oligomer Characterization by Addition of Mass counts protein subunits by selectively shaving a protein mass tag added to a protein subunit via a short pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2b06e5fde2328b70fe68a6dd5c8acb
https://doi.org/10.1002/pro.562
https://doi.org/10.1002/pro.562
Publikováno v:
Proceedings of the National Academy of Sciences. 105:376-381
Large conductance voltage and Ca 2+ -dependent K + channels (BK Ca ) are activated by both membrane depolarization and intracellular Ca 2+ . Recent studies on bacterial channels have proposed that a Ca 2+ -induced conformational change within special
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec33fb59a1b558ab08c3e1880c62efda
https://doi.org/10.1073/pnas.0705261105
https://doi.org/10.1073/pnas.0705261105
Autor:
Chris S. Gandhi, Bruce E. Cohen, Xiao-Jie Yao, Lily Yeh Jan, Gayathri Swaminath, Yuh Nung Jan, Arnd Pralle, Brian K. Kobilka, Ehud Y. Isacoff
Publikováno v:
Proceedings of the National Academy of Sciences. 102:965-970
The usefulness of fluorescence in studying protein motions derives from its sensitivity, kinetic resolution, and compatibility with both live cells and physiological assays. Recent advances in microscopy and membrane protein purification have permitt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc0a51ad2eac8f34b7172de8169c9e
https://doi.org/10.1073/pnas.0409469102
https://doi.org/10.1073/pnas.0409469102
Publikováno v:
Neuron. 27:585-595
X-ray crystallography has made considerable recent progress in providing static structures of ion channels. Here we describe a complementary method—systematic fluorescence scanning—that reveals the structural dynamics of a channel. Local protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f9489100ef30bd05c73f4171ae1b2c
https://doi.org/10.1016/s0896-6273(00)00068-4
https://doi.org/10.1016/s0896-6273(00)00068-4
Publikováno v:
Nature. 402:813-817
Voltage-gated ion channels underlie the generation of action potentials and trigger neurosecretion and muscle contraction. These channels consist of an inner pore-forming domain, which contains the ion permeation pathway and elements of its gates, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a126de239aca8af2be1cf4c44b4915ae
https://doi.org/10.1038/45561
https://doi.org/10.1038/45561
Autor:
Jeffrey Braman, Lawrence H. Pinto, Robert A. Lamb, James D. Lear, Chris S. Gandhi, Carol G. Papworth, Gregg R. Dieckmann, William F. DeGrado, Margaret A. Shaughnessy
Publikováno v:
Proceedings of the National Academy of Sciences. 94:11301-11306
The M 2 protein from influenza A virus forms proton-selective channels that are essential to viral function and are the target of the drug amantadine. Cys scanning was used to generate a series of mutants with successive substitutions in the transmem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04518b4cdbda1b39a42c2c9dfad46985
https://doi.org/10.1073/pnas.94.21.11301
https://doi.org/10.1073/pnas.94.21.11301
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e33077 (2012)
PLoS ONE, Vol 7, Iss 3, p e33077 (2012)
Bacteria are subjected to a host of different environmental stresses. One such insult occurs when cells encounter changes in the osmolarity of the surrounding media resulting in an osmotic shock. In recent years, a great deal has been learned about m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4c7e8b903a9c852888f35ac5a04a50
https://pubmed.ncbi.nlm.nih.gov/22427953
https://pubmed.ncbi.nlm.nih.gov/22427953
Autor:
Chris S. Gandhi, Sarah Franklin, Antonios Pantazis, Anoosh Javaherian, Riccardo Olcese, Taleh N. Yusifov
Large-conductance voltage- and Ca^(2+)-dependent K^+ (BK, also known as MaxiK) channels are homo-tetrameric proteins with a broad expression pattern that potently regulate cellular excitability and Ca^(2+) homeostasis. Their activation results from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af88de49dcba64c2682ada024594807
https://resolver.caltech.edu/CaltechAUTHORS:20110620-134932876
https://resolver.caltech.edu/CaltechAUTHORS:20110620-134932876
Publikováno v:
Protein science : a publication of the Protein Society. 20(2)
We have developed a new technique to study the oligomeric state of proteins in solution. OCAM or Oligomer Characterization by Addition of Mass counts protein subunits by selectively shaving a protein mass tag added to a protein subunit via a short pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cdb476d64d42effa6d1c2a43ceebcd3
https://pubmed.ncbi.nlm.nih.gov/21280123
https://pubmed.ncbi.nlm.nih.gov/21280123