Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chris R. Futtner"'
Autor:
Danielle M. Maatouk, Francis Poulat, Ryohei Sekido, S. Alexandra Garcia-Moreno, Chris R. Futtner, Nitzan Gonen, Sophie Wood, Isabella M. Salamone, Shiela C. Samson, Robin Lovell-Badge
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2018, 360 (6396), pp.1469-1473. ⟨10.1126/science.aas9408⟩
Science, American Association for the Advancement of Science, 2018, 360 (6396), pp.1469-1473. ⟨10.1126/science.aas9408⟩
Sox9 regulation during sex determination Sex determination is regulated by the Sox9 gene. During testis differentiation, this gene is directly targeted by the product of the Y chromosome–encoded gene Sry . The regulatory region of Sox9 is complex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa27d26c5145ad64edd4d5543e1df11
https://hal.archives-ouvertes.fr/hal-01974918
https://hal.archives-ouvertes.fr/hal-01974918
Autor:
Nitzan, Gonen, Chris R, Futtner, Sophie, Wood, S Alexandra, Garcia-Moreno, Isabella M, Salamone, Shiela C, Samson, Ryohei, Sekido, Francis, Poulat, Danielle M, Maatouk, Robin, Lovell-Badge
Publikováno v:
Science (New York, N.Y.). 360(6396)
Cell fate decisions require appropriate regulation of key genes. Sox9, a direct target of SRY, is pivotal in mammalian sex determination. In vivo high-throughput chromatin accessibility techniques, transgenic assays, and genome editing revealed sever