Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chris R. Campos"'
Autor:
Jason D. Huber, Thomas P. Davis, Lihong Guo, Michael D. Bentley, Richard D. Egleton, Chris R. Campos, Roberts Michael J, Ken A. Witt
Publikováno v:
Journal of pharmaceutical sciences. 92(7)
The objectives of this study were to examine the effect of poly(ethylene glycol) (PEG) conjugation on the tyrosine residues of biphalin to determine the proper size PEG for optimal efficacy and investigate the antinociceptive profile of PEG-biphalin
Autor:
Chris R. Campos, Richard D. Egleton, Jason D. Huber, Thomas P. Davis, Lindsay K. Borg, Vincent S. Hau
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 283(4)
In this study, we examined the effect of λ-carrageenan-induced inflammatory pain on the functional and structural properties of the rat blood-brain barrier (BBB) over a 72-h time period. Systemic inflammation was induced by an intraplantar injection
Autor:
Jason D. Huber, Thomas P. Davis, Karen S. Mark, Chris R. Campos, Vincent S. Hau, Rachel C. Brown
Publikováno v:
European journal of pharmacology. 450(3)
We investigated three inflammatory agents to establish if these substances elicit a direct effect on the functional and structural integrity of the blood-brain barrier. Cellular cytotoxicity and paracellular permeability were assessed in vitro using
Autor:
Thomas P. Davis, Richard D. Egleton, Carolyn A. Quigley, Melissa J. Seelbach, Tracy A. Brooks, Gwen McCaffrey, Nicole Nametz, William D. Staatz, Chris R. Campos
Publikováno v:
Journal of Neurochemistry. :071106212736002
Tight junctions (TJs) are major components of the blood-brain barrier (BBB) that physically obstruct the interendothelial space and restrict paracellular diffusion of blood-borne substances from the peripheral circulation to the CNS. TJs are dynamic