First Virtual International Congress on Cellular and Organismal Stress Responses, November 5-6, 2020

Autor: Adrienne L. Edkins, Harm H. Kampinga, Linda M. Hendershot, Ruth Scherz-Shouval, Andrew W. Truman, Steven Bergink, Veena Prahlad, Chris Prodromou, Olivier Genest, Antonio De Maio, Gabriele Multhoff, Jill L. Johnson, Brian C. Freeman, Mehdi Mollapour, Jeff Brodsky, Patricija van Oosten-Hawle, Brian S. J. Blagg, Dan Masison, Anastasia Zhuravleva, Kevin A. Morano

Publikováno v: Cell Stress & Chaperones
Cell Stress and Chaperones
Cell Stress and Chaperones, 2021, 26 (2), pp.289-295. ⟨10.1007/s12192-021-01192-7⟩
Cell Stress and Chaperones, Springer Verlag, 2021, 26 (2), pp.289-295. ⟨10.1007/s12192-021-01192-7⟩

Members of the Cell Stress Society International (CSSI), Patricija van Oosten-Hawle (University of Leeds, UK), Mehdi Mollapour (SUNY Upstate Medical University, USA), Andrew Truman (University of North Carolina at Charlotte, USA) organized a new virt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2157c71bd2f03481bb806d4b6d32f004
https://hdl.handle.net/11370/7037eec0-2788-424e-a500-f9cdb68673f3

Abstract B99: Targeting TPR cochaperones of the Hsp90 molecular chaperone complex for specific inhibition

Autor: Paul Workman, Peter Simpson, Chris Prodromou, Steve Matthews, John F. Darby, Swen Hoelder, Swee Y. Sharp, Laurence H. Pearl, Lewis R. Vidler

Publikováno v: Molecular Cancer Therapeutics. 10:B99-B99

The Hsp90 molecular chaperone complex plays an important role in tumour biology by aiding oncogenic client proteins in their stability and activity. Targeted therapeutics that disrupt the Hsp90 function have shown promise in clinical trials (eg 17-al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b14dfa88062991ebb9b220d4a9da724e
https://doi.org/10.1158/1535-7163.targ-11-b99