Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chris Plumpton"'
Autor:
Jeff Hanvey, Susan M. Goldsworthy, Noeleen A. Looney, Jui-Lan Su, Philip Rivers, Thomas A. Kost, Frederick C. Kull, Chris Plumpton, Janet H. Parham, Michael Romanos, Jim Fornwald
Publikováno v:
Journal of Immunological Methods. 291:123-135
A cell-based time-resolved fluorescence (celTRF) immunoassay is described for pre-screening antibodies to G protein-coupled receptor (GPCR) peptides that predicts suitability for immunohistochemistry (IHC). Rat GPCRs were expressed in Saos-2 human os
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a7cd7c42908ec0292c96ef7fdf377f
https://doi.org/10.1016/j.jim.2004.05.006
https://doi.org/10.1016/j.jim.2004.05.006
Autor:
R. A. Killington, Tobias J. Tuthill, Lisa J. Challinor, Sebastian L. Johnston, Nigel A. Sharp, Jerome Burnet, Neil J. Clarke, Edward D. Blair, Laura Dash, Suzanne Barnard, David J. Rowlands, Nikolaos G. Papadopoulos, Chris Plumpton, Ketaki Shah, Patrick Jourdan
Publikováno v:
Journal of General Virology. 84:2829-2836
Human rhinoviruses (HRV) are responsible for the majority of virus infections of the upper respiratory tract. Furthermore, HRV infection is associated with acute exacerbation of asthma and other chronic respiratory diseases of the lower respiratory t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd953cd5358a89b21d2b5dda2f433506
https://doi.org/10.1099/vir.0.19109-0
https://doi.org/10.1099/vir.0.19109-0
Autor:
Barbara Maschera, Keith Paul Ray, Jiirg Tschopp, Filippo Volpe, Laurence Martin, Chris Plumpton, Fabio Martinon, Kimberly Burns, Alan Peter Lewis, Jonathan Clatworthy
Publikováno v:
Nature Cell Biology. 2:346-351
Interleukin-1 (IL-1) is a proinflammatory cytokine that elicits its pleiotropic effects through activation of the transcription factors NF-kappaB and AP-1. Binding of IL-1 to its receptor results in rapid assembly of a membrane-proximal signalling co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e8ea6f59fc9fc3aa870b7a895cc04b
https://doi.org/10.1038/35014038
https://doi.org/10.1038/35014038
Autor:
Simon J. Dowell, Martina Marzioch, Malcolm S. Whiteway, Jeffrey J. Clare, Julia H. White, Andrew J. Brown, Marie-Ange Watson, Diane J. Cousens, Chris Paddon, Susan L. Dyos, M A Romanos, Chris Plumpton
Publikováno v:
Yeast. 16:11-22
The expression of mammalian G protein coupled receptors (GPCRs) in S. cerevisiae provides a powerful assay system for functional analysis, ligand identification and pharmaceutical screening. However, relatively few receptors have been coupled to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775c4cc88a8131b9e1381ffa6b86f520
https://doi.org/10.1002/(sici)1097-0061(20000115)16:1<11::aid-yea502>3.0.co
https://doi.org/10.1002/(sici)1097-0061(20000115)16:1<11::aid-yea502>3.0.co
Autor:
J. Robert Lane, Chris Plumpton, Alan Wise, Graeme Milligan, Stephen Edward Rees, Ian Kinghorn, David Henderson, Dion A. Daniels, Ben Powney
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 22(6)
Production of antisera able to recognize individual heterotrimeric G protein alpha subunits resulted in rapid expansion of information on their distribution and function. However, no antibodies that specifically recognize the active state have been a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f77873112fd76167f9c11123cafa056
https://pubmed.ncbi.nlm.nih.gov/18199696
https://pubmed.ncbi.nlm.nih.gov/18199696
Autor:
R. A. Killington, Edward D. Blair, David J. Rowlands, Jie Zhu, Jürgen Schwarze, Nigel A. Sharp, Michael Hurle, Michael S Pedrick, Jerome Burnet, Michael R. Edwards, Alberto Papi, Juliya Aniscenko, Ross P. Walton, Dallas M. Swallow, Bruno Guy, Clare M. Lloyd, Gaetano Caramori, Sebastian L. Johnston, Nicholas Glanville, Tobias J. Tuthill, Jeffrey Almond, Neil J. Clarke, Katherine Choy, Nathan W. Bartlett, Peter K. Jeffery, Chris Plumpton, Patrick Jourdan, James N Bussell
Publikováno v:
Bartlett, N W, Walton, R P, Edwards, M R, Aniscenko, J, Caramori, G, Zhu, J, Glanville, N, Choy, K J, Jourdan, P, Burnet, J, Tuthill, T J, Pedrick, M S, Hurle, M J, Plumpton, C, Sharp, N A, Bussell, J N, Swallow, D M, Schwarze, J, Guy, B, Almond, J W, Jeffery, P K, Lloyd, C M, Papi, A, Killington, R A, Rowlands, D J, Blair, E D, Clarke, N J & Johnston, S L 2008, ' Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation ', Nature Medicine, vol. 14, no. 2, pp. 199-204 . https://doi.org/10.1038/nm1713
Rhinoviruses cause serious morbidity and mortality as the major etiological agents of asthma exacerbations and the common cold. A major obstacle to understanding disease pathogenesis and to the development of effective therapies has been the lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76d8bee795d6f65c3a2bc5456a1bf24
http://hdl.handle.net/11392/523278
http://hdl.handle.net/11392/523278
