Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Chris Neff"'
Autor:
Matthew D Dyer, Chris Neff, Max Dufford, Corban G Rivera, Donna Shattuck, Josep Bassaganya-Riera, T M Murali, Bruno W Sobral
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12089 (2010)
Bacillus anthracis, Francisella tularensis, and Yersinia pestis are bacterial pathogens that can cause anthrax, lethal acute pneumonic disease, and bubonic plague, respectively, and are listed as NIAID Category A priority pathogens for possible use a
Externí odkaz:
https://doaj.org/article/8c55bfc9b75b48949ded5f04b342dc83
Autor:
Carsten Denkert, Marcel Romey, Brad Swedlund, Akira Hattesohl, Julia Teply-Szymanski, Stefan Kommoss, Kristin Kaiser, Annette Staebler, Andreas du Bois, Albert Grass, Christiane Knappmeyer, Florian Heitz, Cara Solimeno, Thomas Ebel, Philipp Harter, Frederik Marmé, Paul Jank, Timo Gaiser, Chris Neff, Uwe Wagner, Kirsten M. Timms, Fiona Rodepeter
Publikováno v:
The Journal of Molecular Diagnostics. 24:1254-1263
Autor:
Andrea L. Richardson, Daniel P. Silver, James M. Ford, Judy E. Garber, Anne-Renee Hartman, Jerry S. Lanchbury, Joshua T. Jones, Victor Abkevich, Chris Neff, Diana Iliev, Zaina Sangale, Alexander Gutin, April Greene-Colozzi, Paula D. Ryan, Steven J. Isakoff, Nadine M. Tung, Eric P. Winer, William T. Barry, Zoltan Szallasi, Kristin C. Jensen, Gordon B. Mills, Bryan Hennessy, Julia Reid, Kirsten M. Timms, Melinda L. Telli
Figure S1. Summary of HRD testing in PrECOG and combined cisplatin cohorts; Figure S2. Distribution of HRD scores in PrECOG and combined cisplatin cohorts; Figure S3. Performance of HRD in predicting response in PrECOG and combined cisplatin cohorts;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a225799f97d719f6f2d801e80037690
https://doi.org/10.1158/1078-0432.22456529.v1
https://doi.org/10.1158/1078-0432.22456529.v1
Autor:
Andrea L. Richardson, Daniel P. Silver, James M. Ford, Judy E. Garber, Anne-Renee Hartman, Jerry S. Lanchbury, Joshua T. Jones, Victor Abkevich, Chris Neff, Diana Iliev, Zaina Sangale, Alexander Gutin, April Greene-Colozzi, Paula D. Ryan, Steven J. Isakoff, Nadine M. Tung, Eric P. Winer, William T. Barry, Zoltan Szallasi, Kristin C. Jensen, Gordon B. Mills, Bryan Hennessy, Julia Reid, Kirsten M. Timms, Melinda L. Telli
Purpose:BRCA1/2-mutated and some sporadic triple-negative breast cancers (TNBC) have DNA repair defects and are sensitive to DNA-damaging therapeutics. Recently, three independent DNA-based measures of genomic instability were developed on the basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c81fbdd0b18e828c6eb12c4e5d9b613
https://doi.org/10.1158/1078-0432.c.6523340
https://doi.org/10.1158/1078-0432.c.6523340
Autor:
Kirsten M Timms, Lauren Lenz, Chris Neff, Cara Solimeno, Darl Flake, Judy C Boughey, Matthew P Goetz, Andrea Richardson, Anna Maria Storniolo, Alexander Gutin, Roisin M Connolly, Vered Stearns, Jerry S Lanchbury
Publikováno v:
Cancer Research. 82:P5-13
Background: Patients with homologous recombin ation (HR) deficient tumors may benefit from treatment with DNA damaging agents. Markers of genomic instability can be used to identify HR deficiency, including a 3-biomarker Genomic Instability Score (GI
Autor:
Anil K. Sood, Robert L. Coleman, Selanere Mangala, Placede Tshiaba, Keith A. Baggerly, Wei Hu, Thomas P. Conrads, Kirsten Timms, Chris Neff, Ying Wang, Kari L. Ring, Shannon N. Westin, Karen H. Lu, K.M. Darcy, R.L. Dood, G.L. Maxwell, Russell Broaddus, Gabriel Lopez-Berestein, Shannon Gallagher, Jean H. Siedel
Publikováno v:
Gynecol Oncol
BACKGROUND: Homologous recombination deficiency (HRD) score is related to chemotherapy response in some cancers, but its role in endometrial cancer in not known. We determined frequency and clinical significance of alterations in the HR pathway in en
Autor:
Joshua J. Gruber, Kirsten Timms, Nadine Tung, Vered Stearns, Daniel P. Silver, Andrea L. Richardson, Ryan Bernhisel, Judy Garber, Shaveta Vinayak, James M. Ford, Melinda L. Telli, Virginia G. Kaklamani, Chris Neff, Steven J. Isakoff, Sunil Badve, William J. Gradishar, Sylvia Adams, Roisin M. Connolly, Charles Chu
Publikováno v:
Clinical Cancer Research. 26:2704-2710
Purpose: Patients with triple-negative breast cancer (TNBC) with homologous recombination deficient tumors achieve significantly higher pathologic complete response (pCR) rates when treated with neoadjuvant platinum-based therapy. Tumor-infiltrating
Autor:
Carsten, Denkert, Marcel, Romey, Brad, Swedlund, Akira, Hattesohl, Julia, Teply-Szymanski, Stefan, Kommoss, Kristin, Kaiser, Annette, Staebler, Andreas, du Bois, Albert, Grass, Christiane, Knappmeyer, Florian, Heitz, Cara, Solimeno, Thomas, Ebel, Philipp, Harter, Frederik, Marmé, Paul, Jank, Timo, Gaiser, Chris, Neff, Uwe, Wagner, Kirsten M, Timms, Fiona, Rodepeter
Publikováno v:
The Journal of molecular diagnostics : JMD. 24(12)
The diagnostic evaluation of homologous recombination deficiency (HRD) is central to define targeted therapy strategies for patients with ovarian carcinoma. We evaluated HRD in 514 ovarian carcinoma samples by next-generation sequencing of DNA librar
Autor:
Dmitry Pruss, Zoltan Szallasi, Gábor Cserni, Janina Kulka, Kirsten Timms, Chris Neff, István Csabai, Orsolya Rusz, József Tímár, Cara Solimeno, Borbála Székely, Tamás Zombori, Miklos Diossy, Zsofia Sztupinszki, Marcin Krzystanek, Erika Tóth, Aron Charles Eklund, Orsolya Kiss, Lilla Reiniger
Publikováno v:
Diossy, M, Reiniger, L, Sztupinszki, Z M, Krzystanek, M, Timms, K M, Neff, C, Solimeno, C, Pruss, D, Eklund, A C, Tóth, E, Kiss, O, Rusz, O, Cserni, G, Zombori, T, Székely, B, Tímár, J, Csabai, I & Szallasi, Z 2018, ' Breast cancer brain metastases show increased levels of genomic aberration based homologous recombination deficiency scores relative to their corresponding primary tumors ', Annals of Oncology, vol. 29, no. 9, pp. 1948-1954 . https://doi.org/10.1093/annonc/mdy216
Background Based on its mechanism of action, PARP inhibitor therapy is expected to benefit mainly tumor cases with homologous recombination deficiency (HRD). Therefore, identification of tumor types with increased HRD is important for the optimal use
Autor:
Steven Fiorentino, Matthew E. Smith, Giovanni Hernandez, Ben T. Kligman, Jeb Bevers, Adam D. Marsh, Dirilee Curtis, Chris Neff
Publikováno v:
Geological Society of America Abstracts with Programs.