Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chris Moxham"'
Publikováno v:
Science and Technology of Materials, 30(suppl. 1), 93-98. Elsevier
Preparation process and life service solicitations can cause damage on concrete's internal structure, creating cracks that tend to propagate and increase with time. This poses a risk of failure as water penetrates, corroding the rebar reducing concre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016bb7cb7fd611e00f8b0b47db81b11f
https://doi.org/10.1016/j.stmat.2018.11.006
https://doi.org/10.1016/j.stmat.2018.11.006
Autor:
Hugh Nuthall, Lily Y. Moy, Candia M. Kenific, Sean P. Ahearn, Damaris Diaz, Elizabeth Helen Kelley, Bethany Hughes, Armetta D. Hill, Adam J. Schell, Nadya Smotrov, Valentina V. Jeliazkova-Mecheva, Chris Moxham, Hua Zhou, Sanjiv J. Shah, Andrew Rosenau, Alexey Rivkin, Sam Kattar, Joey L. Methot, Richard G. Ball, William Brown, Mark S. Shearman, Chaomin Li, Christian Fischer, Alexander A. Szewczak, Sujal V. Deshmukh, Dawn M. Mampreian, Thomas A. Miller, Benito Munoz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:3495-3500
The triazolyl amide γ-secretase modulators are potent alternatives to the cinnamyl amides that have entered the clinic for the treatment of Alzheimer's disease. Herein we build on the lead benzoazepinones described in our prior communication with im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a00409b5294ccf9d203089fa0df9362
https://doi.org/10.1016/j.bmcl.2015.06.032
https://doi.org/10.1016/j.bmcl.2015.06.032
Autor:
Anthony Pennello, Dale L. Ludwig, Xiaodi Ren, David Surguladze, Gregory D. Plowman, Scott W. Eastman, Elizabeth Navarro, Yung-mae Yao, Alan C. Rigby, Chris Moxham, Paul Balderes, Nelusha Amaladas, Tim Mack, Michael Topper
Publikováno v:
Cancer Research. 79:4835-4835
Fibroblast growth factor receptor 3 (FGFR3) has been shown to be constitutively activated in bladder, multiple myeloma, non-small cell lung cancer (NSCLC), glioblastoma multiforme, and cervical cancer through overexpression, point mutations, and tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce956e63af32e94e245f0e2d497ecf5
https://doi.org/10.1158/1538-7445.am2019-4835
https://doi.org/10.1158/1538-7445.am2019-4835
Autor:
George N. Nikov, Flobert Tanga, Chris Moxham, Ziping Yang, Chaomin Li, Richard G. Ball, Joshua Close, Richard W. Heidebrecht, Gloria Y. Kwei, Lin Xu, Laura Surdi, Xiaoliu Geng, Candia Kenefic, Sanjiv J. Shah, Dan F. Savage, Valentina V. Jeliazkova-Mecheva, Jennifer Chapnick, Julie Elizabeth Burke, Solomon Kattar, Bethany Hughes, Lily Y. Moy, Sujal V. Deshmukh, Paul Moses, Damaris Diaz, John Kevin Leach, Paul Tempest, John Hendrix, Amanda Markarewicz, Nadya Smotrov, Ilona Kariv, Michael J. McNevin, Ben Munoz, Mark S. Shearman, Thomas A. Miller
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(9)
Alzheimer’s disease is a major unmet medical need with pathology characterized by extracellular proteinaceous plaques comprised primarily of β-amyloid. γ-Secretase is a critical enzyme in the cellular pathway responsible for the formation of a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d76db0c66a4f7b201b3015ad1e1e6a7
https://pubmed.ncbi.nlm.nih.gov/22483609
https://pubmed.ncbi.nlm.nih.gov/22483609