Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Chris McDermott"'
Autor:
Biniyam G. Demissei, WenJian Lv, Nicholas S. Wilcox, Karyn Sheline, Amanda M. Smith, Kathleen M. Sturgeon, Chris McDermott-Roe, Kiran Musunuru, Bénédicte Lefebvre, Susan M. Domchek, Payal Shah, Bonnie Ky
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveAnimal models suggest that BRCA1/2 mutations increase doxorubicin-induced cardiotoxicity risk but data in humans are limited. We aimed to determine whether germline BRCA1/2 mutations are associated with cardiac dysfunction in breast cancer s
Externí odkaz:
https://doaj.org/article/6a2d2f18394d4f2da6ca9fa01364cce5
Autor:
Katie A. Mitzelfelt, Chris McDermott-Roe, Michael N. Grzybowski, Maribel Marquez, Chieh-Ti Kuo, Michael Riedel, Shuping Lai, Melinda J. Choi, Kurt D. Kolander, Daniel Helbling, David P. Dimmock, Michele A. Battle, Chuanchau J. Jou, Martin Tristani-Firouzi, James W. Verbsky, Ivor J. Benjamin, Aron M. Geurts
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 491-499 (2017)
Genome editing in induced pluripotent stem cells is currently hampered by the laborious and expensive nature of identifying homology-directed repair (HDR)-modified cells. We present an approach where isolation of cells bearing a selectable, HDR-media
Externí odkaz:
https://doaj.org/article/83b03a2018cb4c5d8fd10a28c1724404
Autor:
Chris McDermott-Roe, Marion Leleu, Glenn C Rowe, Oleg Palygin, John D Bukowy, Judy Kuo, Monika Rech, Steffie Hermans-Beijnsberger, Sebastian Schaefer, Eleonora Adami, Esther E Creemers, Matthias Heinig, Blanche Schroen, Zoltan Arany, Enrico Petretto, Aron M Geurts
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170458 (2017)
Mitochondrial dysfunction contributes to myriad monogenic and complex pathologies. To understand the underlying mechanisms, it is essential to define the full complement of proteins that modulate mitochondrial function. To identify such proteins, we
Externí odkaz:
https://doaj.org/article/32ee4dc91d374bd4874942d7b45e8553
Autor:
Enrico Petretto, Leonardo Bottolo, Sarah R Langley, Matthias Heinig, Chris McDermott-Roe, Rizwan Sarwar, Michal Pravenec, Norbert Hübner, Timothy J Aitman, Stuart A Cook, Sylvia Richardson
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 4, p e1000737 (2010)
The majority of expression quantitative trait locus (eQTL) studies have been carried out in single tissues or cell types, using methods that ignore information shared across tissues. Although global analysis of RNA expression in multiple tissues is n
Externí odkaz:
https://doaj.org/article/fa03e8369f94439c891b89f213b42112
Doxorubicin (DOX) is an efficacious chemotherapy compound used to treat various cancers which elicits severe side effects, including heart failure. Uptake of DOX by cardiomyocytes causes metabolic dysfunction and cell death but causal mechanisms rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::613b8b72d51f3ea6c9be4f6dfa3b715a
https://doi.org/10.1101/2022.08.01.502373
https://doi.org/10.1101/2022.08.01.502373
Autor:
Jochem Helleman, Barbara Johnson, Cory Holdom, Esther Hobson, Deirdre Murray, Frederik J. Steyn, Shyuan T. Ngo, Anjali Henders, Madhura B. Lokeshappa, Johanna M. A. Visser-Meily, Leonard H. van den Berg, Orla Hardiman, Anita Beelen, Chris McDermott, Ruben P. A. van Eijk
Introduction To capture the patient’s attitude toward remote monitoring of motor neuron disease (MND) in care and clinical trials, and their concerns and preferences regarding the use of digital technology. Methods We performed an international mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee309e7c0d2151c430bdba4bb3b0932
Autor:
Chris McDermott-Roe, Bonnie Ky
Publikováno v:
Current Cardiovascular Risk Reports. 14
Anthracyclines are potent and widely used anti-cancer compounds which carry a significant risk of cardiotoxicity. Genetic background is a key determinant of risk susceptibility and identifying causal genes and polymorphisms is an area of intense and
Autor:
Wenjun Li, Wenjian Lv, Kiran Musunuru, Chris McDermott-Roe, Anjali T. Owens, Nataliya B. Petrenko, Lyon Qiao
Publikováno v:
Circulation. 138(24)
Autor:
Chris McDermott
Publikováno v:
Impact. 2018:6-8
Autor:
Bruce A. Molitoris, Bradley T. Endres, George J. Rhodes, Aron M. Geurts, Chris McDermott-Roe, Ruben M. Sandoval, Alexander Staruschenko, Oleg Palygin, Malgorzata M. Kamocka, Silvia B. Campos-Bilderback
Publikováno v:
American Journal of Physiology-Renal Physiology. 313:F163-F173
Hypertension is one of the most prevalent diseases worldwide and a major risk factor for renal failure and cardiovascular disease. The role of albuminuria, a common feature of hypertension and robust predictor of cardiorenal disorders, remains incomp