Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Chris Man"'
Autor:
Zi-Lu Huang, Zhi-Gang Liu, Qi Lin, Ya-Lan Tao, Xinzhuoyun Li, Patricia Baxter, Jack MF Su, Adekunle M. Adesina, Chris Man, Murali Chintagumpala, Wan Yee Teo, Yu-Chen Du, Yun-Fei Xia, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101988- (2024)
Radiation is one of the standard therapies for pediatric high-grade glioma (pHGG), of which the prognosis remains poor. To gain an in-depth understanding of biological consequences beyond the classic DNA damage, we treated 9 patient-derived orthotopi
Externí odkaz:
https://doaj.org/article/42c4611929cf4552aa6cf7dffa17679b
Autor:
Tomislav Baček, Mingrui Sun, Hengchang Liu, Zhongxiang Chen, Chris Manzie, Etienne Burdet, Dana Kulić, Denny Oetomo, Ying Tan
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-22 (2024)
Abstract Numerous studies have explored the biomechanics and energetics of human walking, offering valuable insights into how we walk. However, prior studies focused on changing external factors (e.g., walking speed) and examined group averages and t
Externí odkaz:
https://doaj.org/article/e4ec8dc5def448459cf3c5893fcfbcd8
Autor:
Huiyuan Zhang, Frank K. Braun, Jianhua Yang, Holly Lindsay, Yuchen Du, Xiao-Nan Li, Litian Yu, Yulun Huang, Xiumei Zhao, Sibo Zhao, Laszlo Perlaky, Ching C. Lau, Xingding Zhang, Lin Qi, Patricia Baxter, Chris Man, Mari Kogiso, Wan-Yee Teo, Jack Su, Zhigang Liu, Adekunle M. Adesina, Murali Chintagumpala
Publikováno v:
Cancer Lett
Brain tumor is the leading cause of cancer related death in children. Clinically relevant animals are critical for new therapy development. To address the potential impact of animal gender on tumorigenicity rate, xenograft growth and in vivo drug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f358d3dd08934616954e21febefbe03
https://europepmc.org/articles/PMC10324102/
https://europepmc.org/articles/PMC10324102/
Autor:
Laszlo Perlaky, Zhigang Liu, Adekunle M. Adesina, Jianhua Yang, Holly Lindsay, Jack Mf Su, Xiumei Zhao, Huiyuan Zhang, Murali Chintagumpala, Mari Kogiso, Wan-Yee Teo, Xiao-Nan Li, Yuchen Du, Ching C. Lau, Patricia Baxter, Xingding Zhang, Sibo Zhao, Frank K. Braun, Litian Yu, Yulun Huang, Chris Man, Lin Qi
Publikováno v:
Cancer Lett
Brain tumor is the leading cause of cancer related death in children. Clinically relevant animals are critical for new therapy development. To address the potential impact of animal gender on tumorigenicity rate, xenograft growth and in vivo drug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a80fdb303acdc6007856c0a72423e8
https://europepmc.org/articles/PMC10306089/
https://europepmc.org/articles/PMC10306089/
Autor:
Marcel Kool, Patricia Baxter, Chris Man, Adesina Adekunle, Murali Chintagumpala, Yuchen Du, Holly Lindsay, Stefan M. Pfister, Jianhua yang, Mari Kogiso, Sibo Zhao, Lin Qi, Zhong Wang, Yulun Huang, Huiyuan Zhang, Williams Parsons, Laszlo Perlaky, Sebastian Brabetz, Lei Huang, Frank K. Braun, Xiao-Nan Li, Youxin Zhou, Wan-Yee Teo, Jack Su
Publikováno v:
Neuro Oncol
Diffuse invasion is one of the key features that make GBM particularly difficult to treat. We hypothesize that direct comparison of matched invasive (GBMINV) and tumor core GBM cells (GBMTC) would facilitate the discovery of drivers of pediatric GBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82efe1243855a2c481f5270152f0ed53
https://doi.org/10.1093/neuonc/noz175.793
https://doi.org/10.1093/neuonc/noz175.793
Autor:
Hong Zhao, Lin Qi, Sarah Injac, Stephen T. C. Wong, Chris Man, Lei Huang, Ching C. Lau, Xiao-Nan Li, Mari Kogiso
Medulloblastoma (MB) is the most common malignant brain tumor of childhood. While the current standard care for MB leads to long term survival in approximately 75 % of patients; recurrent and refractory MB continues to have dismal outcomes and long t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe1bf22df01ba2c33a06e533704062e
https://europepmc.org/articles/PMC5692662/
https://europepmc.org/articles/PMC5692662/
Publikováno v:
Blood. 134:3731-3731
Despite aggressive chemotherapy, relapse occurs in almost half of children with acute myeloid leukemia (AML), with very dismal survival. Novel and mechanism-driven therapies are desperately needed to conquer chemotherapy resistance and leukemic stemn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c3d27f3d50f7882b9ccb77d300549f
https://doi.org/10.1182/blood-2019-129074
https://doi.org/10.1182/blood-2019-129074
Autor:
Terzah M. Horton, Rikhia Chakraborty, Chris Man, Carl E. Allen, Harshal Abhyankar, Elmoataz Abdel Fattah, Kenneth L. McClain, Olive S. Eckstein, Kala Y. Kamdar, Howard Lin, Nmazuo W. Ozuah, Jennifer E. Agrusa, Brooks Scull
Publikováno v:
Blood. 134:2773-2773
Introduction: Pathogenic Hodgkin Reed-Sternberg (HRS) cells constitute approximately 1% of Hodgkin lymphoma (HL) tumor cells. Studies characterizing genomic lesions and gene expression of HRS gene cells have been limited due to technical challenges o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d9418540f49c324713bc8319a621d52
https://doi.org/10.1182/blood-2019-125982
https://doi.org/10.1182/blood-2019-125982
Autor:
Melissa L. Bondy, Christoffer Johansen, Chris Man, Beatrice Melin, Jonine L. Bernstein, Jill S. Barnholtz-Sloan, Michael Kosteljanetz, Lisa M. DeAngelis, Eastwood Leung, Christina Corpuz, Lindsay B. Robertson, Lucie McCoy, Yanhong Liu, Mark R. Gilbert, Amanda L. Rynearson, Georgina Armstrong, Roger Henriksson, Fay J. Hosking, Jeffrey S. Weinberg, Hanne Bødtcher, Lili Aslanov, Kenneth Aldape, Elli Papaemmanuil, Revital Bar Sade Bruchim, Robert Yu, Helle Broholm, Galit Hirsh Yechezkel, Dora Il'yasova, Bridget J. McCarthy, Erika Florendo, Michael E. Scheurer, Joellen M. Schildkraut, Gene Barnett, Margaret Wrensch, Karen Devine, Rose Lai, John K. Wiencke, Elizabeth B. Claus, Ulrika Andersson, Ching C. Lau, Sivashankarappa Gurusiddappa, Sanjay Shete, Ping Yang, Andrew E. Sloan, Sara H. Olson, Rita Cheng, Nicholas A. Vick, Rudy Guerra, Siegal Sadetzki, Faith G. Davis, Joseph L. Wiemels, Delcia Rivas, Thomas Brännström, Yingli Wolinsky, Caleb F. Davis, Christopher I. Amos, Erica Schubert, Robert B. Jenkins, Richard S. Houlston
Publikováno v:
Cancer Research. 71:7568-7575
Gliomas, which generally have a poor prognosis, are the most common primary malignant brain tumors in adults. Recent genome-wide association studies have shown that inherited susceptibility plays a role in the development of glioma. Although first-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234a9810cb0fa560a03f41d3e978ac98
https://doi.org/10.1158/0008-5472.can-11-0013
https://doi.org/10.1158/0008-5472.can-11-0013
Autor:
Todd A. Alonzo, Yi-Cheng Wang, Padmini Narayanan, Soheil Meshinchi, Michele S. Redell, Robert B. Gerbing, Rhonda E. Ries, Chris Man
Publikováno v:
Blood. 132:1510-1510
Pediatric AML has a relapse rate approaching 40%, indicating that resistance to chemotherapy remains a critical problem. We are focused on identifying and overcoming environment-mediated mechanisms of resistance. We previously reported that the sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a147d76939aa79d638af607ec0bd14c
https://doi.org/10.1182/blood-2018-99-118771
https://doi.org/10.1182/blood-2018-99-118771