Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Chris Macdonald"'
Autor:
Martha S. C. Xelhuantzi, Daniel Ghete, Amy Milburn, Savvas Ioannou, Phoebe Mudd, Grant Calder, José Ramos, Peter J. O'Toole, Paul G. Genever, Chris MacDonald
Publikováno v:
Biology Open, Vol 13, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/528342c3aad84d3fb4e5b6a0af416b22
Autor:
Patrick Reith, Svenja Braam, Niek Welkenhuysen, Sarah Lecinski, Jack Shepherd, Chris MacDonald, Mark C. Leake, Stefan Hohmann, Sviatlana Shashkova, Marija Cvijovic
Publikováno v:
Microorganisms, Vol 10, Iss 3, p 590 (2022)
Lithium salts are used in the treatment of mood disorders, cancer, and Alzheimer’s disease. It has been shown to prolong life span in several phyla; however, not yet in budding yeast. In our study, we investigate the influence of lithium on yeast c
Externí odkaz:
https://doaj.org/article/6310dbe7c49e4a6db65b6e2d26c339a2
Autor:
Konstantina Amoiradaki, Kate R. Bunting, Katherine M. Paine, Josephine E. Ayre, Karen Hogg, Kamilla M. E. Laidlaw, Chris MacDonald
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12477 (2021)
Intracellular trafficking pathways control residency and bioactivity of integral membrane proteins at the cell surface. Upon internalisation, surface cargo proteins can be delivered back to the plasma membrane via endosomal recycling pathways. Recycl
Externí odkaz:
https://doaj.org/article/ea2cd7d020234a359aaee50b401a06dc
Autor:
Pat Hoddinott, Alex Pollock, Alicia O'Cathain, Isabel Boyer, Jane Taylor, Chris MacDonald, Sandy Oliver, Jenny L. Donovan
Publikováno v:
F1000Research, Vol 7 (2018)
International government guidance recommends patient and public involvement (PPI) to improve the relevance and quality of research. PPI is defined as research being carried out ‘with’ or ‘by’ patients and members of the public rather than ‘
Externí odkaz:
https://doaj.org/article/be4db5749ad64ee7a3e661d80fe82f70
Autor:
Peng Xu, Hannah M Hankins, Chris MacDonald, Samuel J Erlinger, Meredith N Frazier, Nicholas S Diab, Robert C Piper, Lauren P Jackson, Jason A MacGurn, Todd R Graham
Publikováno v:
eLife, Vol 6 (2017)
The COPI coat forms transport vesicles from the Golgi complex and plays a poorly defined role in endocytic trafficking. Here we show that COPI binds K63-linked polyubiquitin and this interaction is crucial for trafficking of a ubiquitinated yeast SNA
Externí odkaz:
https://doaj.org/article/e86d0fb2b2b3432b834acaa7444ecda2
Autor:
Hari B Kamadurai, Yu Qiu, Alan Deng, Joseph S Harrison, Chris MacDonald, Marcelo Actis, Patrick Rodrigues, Darcie J Miller, Judith Souphron, Steven M Lewis, Igor Kurinov, Naoaki Fujii, Michal Hammel, Robert Piper, Brian Kuhlman, Brenda A Schulman
Publikováno v:
eLife, Vol 2 (2013)
Ubiquitination by HECT E3 enzymes regulates myriad processes, including tumor suppression, transcription, protein trafficking, and degradation. HECT E3s use a two-step mechanism to ligate ubiquitin to target proteins. The first step is guided by inte
Externí odkaz:
https://doaj.org/article/ee078a0126a4411894d3182965482e78
Autor:
Chris Macdonald
Publikováno v:
Research in Psychology and Behavioral Sciences. 11:7-11
Autor:
Ilya Andreev, Kamilla M. E. Laidlaw, Simone M. Giovanetti, Guillaume Urtecho, Daniel Shriner, Joshua S. Bloom, Chris MacDonald, Meru J. Sadhu
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Secreted protein toxins are widely used weapons in conflicts between organisms. Elucidating how organisms genetically adapt to defend themselves against these toxins is fundamental to understanding the coevolutionary dynamics of competing organisms.
Publikováno v:
Traffic (Copenhagen, Denmark)
Cell surface membrane proteins perform diverse and critical functions and are spatially and temporally regulated by membrane trafficking pathways. Although perturbations in these pathways underlie many pathologies, our understanding of these pathways
The yeast plasma membrane (PM) is organised into specific subdomains that regulate surface membrane proteins. Surface transporters actively uptake nutrients in particular regions of the PM where they are also susceptible to substrate induced endocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93131bc77d43f44ee66615d8f13d9479
https://doi.org/10.1101/2022.08.09.503340
https://doi.org/10.1101/2022.08.09.503340