Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chris M. Lock"'
Autor:
Robert Harold Bateman, Simon J. Gaskell, Károly Vékey, Gareth Brenton, Zdenek Herman, John F. J. Todd, Jonathan M. Curtis, Eddie Clayton, R. M. Elliott, Chris M. Lock, Brian N. Green, Iwan W. Griffiths, Rich Kondrat, Deepak Mathur, Bob Boyd, Philip Jonathan, Mila Laušević, G. A. Errock
Publikováno v:
Rapid Communications in Mass Spectrometry. 30:1253-1264
Autor:
Deepak Mathur, John F. J. Todd, Károly Vékey, Bob Boyd, Rich Kondrat, Philip Jonathan, Robert Harold Bateman, Gareth Brenton, Zdenek Herman, Chris M. Lock, R. M. Elliott, Mila Laušević, Simon J. Gaskell, Iwan W. Griffiths, Brian N. Green, Jonathan M. Curtis, Eddie Clayton, G. A. Errock
Publikováno v:
Journal of mass spectrometry : JMS. 51(6)
Publikováno v:
Journal of the American Society for Mass Spectrometry. 16:176-182
This article presents a comparative study of the performance, operational, and instrumental characteristics of AP and vacuum MALDI for the analysis of peptides and protein digests. Spectra generated with the two ion sources were surprisingly similar,
Autor:
Michael E. Wright, Hookeun Lee, Timothy J. Griffin, Jeffrey A. Ranish, Iryna Chervetsova, Chris M. Lock, Xiao jun Li, Alpesh A. Patel, Ruedi Aebersold, Sharon S. Chen
Publikováno v:
Analytical Chemistry. 75:867-874
The goal of quantitative proteomics is to determine the identity and relative quantity of each protein present in two or more complex protein samples. Here we describe a novel approach to quantitative proteomics. It is based on a highly accurate algo
Autor:
Chris M. Lock, Michael A. Baldwin, Katalin F. Medzihradszky, Bill Fisher, Tina A. Settineri, Alma L. Burlingame
Publikováno v:
Analytical Chemistry. 73:1707-1720
The design and operation of a novel UV-MALDI ionization source on a commercial QqoaTOF mass spectrometer (Applied Biosystem/MDS Sciex QSTAR Pulsar) is described. Samples are loaded on a 96-well target plate, the movement of which is under software co
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:1744-1754
The technique of solid phase microextraction (SPME) combined on-line with high performance liquid chromatography/mass spectrometry (HPLC/MS) has been applied to the analysis of seven tetracycline analogues. Rapid baseline separation was achieved in u
Autor:
Edward W. Dyer, Chris M. Lock
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:422-431
A PC-based simulation to study the transmission properties of ions through quadrupolar collision cells has been developed. The simulation is based on the ion optics software SIMION 6.0, which enables three-dimensional (3D) representations of any geom
Autor:
Edward W. Dyer, Chris M. Lock
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:432-448
An investigation into the performance characteristics of various designs of novel quadrupolar collision cells possessing axial fields has been undertaken. Among the advantages of such devices possessing conical, tilted or segmented rod geometries is
Autor:
Dietrich A. Volmer, Chris M. Lock
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:157-164
A series of polyether ionophores (lasalocid, monensin-A, narasin-A and salinomycin) was investigated by electrospray ionization (ESI) tandem mass spectrometry (MS/MS). A fast short-column liquid chromatographic (LC) method, using a ternary gradient s
Publikováno v:
Scopus-Elsevier
We describe the coupling of a microfabricated fluidic device to an electrospray ionization (ESI) quadrupole time-of-flight mass spectrometer (QqTOFMS) for the identification of protein samples. The microfabricated devices consisted of three reservoir