Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chris M. Egan"'
Autor:
Fatima Aloraifi, James Geraghty, Jonah McGreevy, Trudi McDevitt, Elaine Kenny, Marie Meany, Rui Martiniano, Daniel G. Bradley, Russell L. McLaughlin, Chris M. Egan, Nuala Cody, Adrian P. Bracken, Andrew Green
Publikováno v:
FEBS Journal. 282:3424-3437
The identification of the breast cancer susceptibility genes BRCA1 and BRCA2 enhanced clinicians' ability to select high-risk individuals for aggressive surveillance and prevention, and led to the development of targeted therapies. However, BRCA1/2 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f34a08d72f29e93f9a95668f14db177
https://doi.org/10.1111/febs.13352
https://doi.org/10.1111/febs.13352
Autor:
Gundula Streubel, Michael J. Dolan, Vilma Rraklli, Ulrika Nyman, David J. O'Connell, Siobhán A. Turner, Naomi Chadderton, Johan Holmberg, Kristian Helin, Julie Skotte, Adrian P. Bracken, Klaus Hansen, Chris M. Egan, Gwyneth Jane Farrar
Publikováno v:
Developmental Cell. 26(3):223-236
SummaryThe chromatin remodeler CHD5 is expressed in neural tissue and is frequently deleted in aggressive neuroblastoma. Very little is known about the function of CHD5 in the nervous system or its mechanism of action. Here we report that depletion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c8519ca6eedd8d6e8f8371718392aa
Autor:
Chris M. Egan, Eiseart J. Dunne, Maike C. Jürgens, Lianhua Piao, Gerard Cagney, Siobhán A. Turner, Neil M. Ferguson, Xiaobing Shi, Kieran Wynne, Gerard L. Brien, Amanda J. Lohan, Adrian P. Bracken, Guillermo Gambero, Krishna M. Sinha, Brendan J. Loftus, Emilia Jerman, David J. O'Connell
Publikováno v:
Nature Structural & Molecular Biology. 19:1273-1281
Polycomb group proteins are repressive chromatin modifiers with essential roles in metazoan development, cellular differentiation and cell fate maintenance. How Polycomb proteins access active chromatin to confer transcriptional silencing during line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea30d27325b15563ed169e344f57ddf
https://doi.org/10.1038/nsmb.2449
https://doi.org/10.1038/nsmb.2449
Publikováno v:
Methods in Molecular Biology ISBN: 9781617792885
Fluorescence microscopy is an important and fundamental tool for biomedical research. Optical microscopy is almost non-invasive and allows highly spatially resolved images of organisms, cells, macromolecular complexes, and biomolecules to be obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7503ef605094e21e69a6493dd4bbce8
https://doi.org/10.1007/978-1-61779-289-2_12
https://doi.org/10.1007/978-1-61779-289-2_12
Autor:
Ulrika Nyman, Siobhán A. Turner, Hansen Klaus, David J. O'Connell, Farrar Gwyneth Jane, Naomi Chadderton, Michael J. Dolan, Gundula Streubel, Kristian Helin, Julie Skotte, Vilma Rraklli, Johan Holmberg, Chris M. Egan, Adrian P. Bracken
Publikováno v:
Cancer Research. 73:PR12-PR12
The chromatin remodeler CHD5 is expressed in neural tissues and is frequently deleted in aggressive neuroblastoma. Very little is known about the normal function of CHD5, its mechanism of action or how its deletion may contribute to neuroblastoma. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0edce59d4ba65af1fac39a4cb37affca
https://doi.org/10.1158/1538-7445.cec13-pr12
https://doi.org/10.1158/1538-7445.cec13-pr12