Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chris Lindsay"'
Autor:
Chris Lindsay, Mano Sitsapesan, Wei Mun Chan, Elisa Venturi, William Welch, Maria Musgaard, Rebecca Sitsapesan
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract ATP is an essential constitutive regulator of cardiac ryanodine receptors (RyR2), enabling small changes in cytosolic Ca2+ to trigger large changes in channel activity. With recent landmark determinations of the full structures of RyR1 (skel
Externí odkaz:
https://doaj.org/article/a9586cc41ca240059c5cc002b05afc15
Autor:
Chen-Hung Lee, Daniel Hunt, Julien George Roth, Ching-Chi Chiu, Riley A. Suhar, Bauer L. LeSavage, Alexis Jane Seymour, Chris Lindsay, Brad A. Krajina, Yi-Tung Chen, Kuo-Hsuan Chang, I-Chang Hsieh, Pao-Hsien Chu, Ming-Shien Wen, Sarah C. Heilshorn
Publikováno v:
Biomaterials. 291
Exosome-based regenerative therapies are potentially easier to manufacture and safer to apply compared to cell-based therapies. However, many questions remain about how to bio-manufacture reproducible and potent exosomes using animal-free reagents. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0386f74b3a6e6c0be8e900ba19bb49c6
https://pubmed.ncbi.nlm.nih.gov/36343608
https://pubmed.ncbi.nlm.nih.gov/36343608
Publikováno v:
British journal of pharmacologyREFERENCES. 179(21)
Statins, inhibitors of HMG-CoA reductase, are mainstay treatment for hypercholesterolaemia. However, muscle pain and weakness prevent many patients from benefiting from their cardioprotective effects. We previously demonstrated that simvastatin activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b058c40320327df26d41d281ffb5c1
https://pubmed.ncbi.nlm.nih.gov/35703154
https://pubmed.ncbi.nlm.nih.gov/35703154
Autor:
Chris Lindsay, Rebecca Sitsapesan, Elisa Venturi, Paul D. Allen, Ahmed Alhussni, Thomas M. Humberstone, Charalampos Sigalas, Abigail D. Wilson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7422c37cb3e34670992b5c3407d98204
https://ora.ox.ac.uk/objects/uuid:14c046b3-4896-4d37-b812-3f3076257e3f
https://ora.ox.ac.uk/objects/uuid:14c046b3-4896-4d37-b812-3f3076257e3f
Background and purpose Statins, inhibitors of HMG-CoA reductase, are mainstay treatment for hypercholesterolemia. However, muscle pain and weakness prevent many patients from benefiting from their cardioprotective effects. We previously demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ca3e0a39eb62d53971baea8fa3d203
https://doi.org/10.22541/au.162729999.96753669/v1
https://doi.org/10.22541/au.162729999.96753669/v1
Autor:
Jan Eckhardt, Pawel Pelczar, Ahmed Alhussni, Thomas M. Humberstone, Christoph Bachmann, Susan Treves, Rebecca Sitsapesan, Alexis Ruiz, Abigail D. Wilson, Simona Boncompagni, Laura Pietrangelo, Elisa Venturi, Moran Elbaz, Francesco Zorzato, Chris Lindsay
Publikováno v:
Human Molecular Genetics. 28:2987-2999
Recessive ryanodine receptor 1 (RYR1) mutations cause congenital myopathies including multiminicore disease (MmD), congenital fiber-type disproportion and centronuclear myopathy. We created a mouse model knocked-in for the Q1970fsX16+A4329D RYR1 muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f238d432c7964b8980160ef0f06dde
https://doi.org/10.1093/hmg/ddz092
https://doi.org/10.1093/hmg/ddz092
Autor:
Chris Lindsay
In his account of what he calls the ‘mechanical principles’ of action, Thomas Reid distinguishes between deliberate, willed actions and those caused by instincts or habits. He holds that that agents can only be held morally responsible with respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc4a3a601b2e51a16ddb4ad414d1992
https://eprints.gla.ac.uk/196579/7/196579.pdf
https://eprints.gla.ac.uk/196579/7/196579.pdf
Publikováno v:
Biophysical Journal. 114:621a-622a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6076f60020d5cedb90bd0d72ca37f11
https://doi.org/10.1016/j.bpj.2017.11.3361
https://doi.org/10.1016/j.bpj.2017.11.3361
Autor:
Mano Sitsapesan, Rebecca Sitsapesan, Chris Lindsay, Maria Musgaard, Elisa Venturi, W M Chan, William Welch
Publikováno v:
Biophysical Journal. 116:42a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca7ec8ec737c0c4037835b1b4c8c0e3
https://doi.org/10.1016/j.bpj.2018.11.271
https://doi.org/10.1016/j.bpj.2018.11.271