Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Chris L.E. Broekkamp"'
Autor:
Thijs de Boer, Chris L.E. Broekkamp, Jan W. van Nispen, Jane M. L. van der Werf‐Pieters, Pedro H. H. Hermkens, Harry C. J. Ottenheijm
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 112:95-106
The design cycle of peptidomimetics having CCK-A agonistic activity is discussed. The phases of this strategic approach are discussed briefly and results obtained either in our laboratories or by other groups are elaborated in this framework. Most of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b165738c495cb3b0a8ae536671c8538
https://doi.org/10.1002/recl.19931120205
https://doi.org/10.1002/recl.19931120205
Publikováno v:
European Neuropsychopharmacology. 9:345-349
The conditioned taste aversion procedure in mice was used to test for blockade of the drug stimulus of the 5-HT1A receptor agonists (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin HBr (8-OH-DPAT), 1-(4-trifluoromethyl-2-pyridinyl)-4- [4-[2-oxo-1-pyrroli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6e3a3738750ad6559cda95ff9a48f6
https://doi.org/10.1016/s0924-977x(99)00004-8
https://doi.org/10.1016/s0924-977x(99)00004-8
Autor:
Jan Gommans, Berend Olivier, Robert A. A. Maes, Theo H. Hijzen, J.A. Bouwknecht, Chris L.E. Broekkamp, Hemmie H.G. Berendsen
Publikováno v:
Psychopharmacology. 140:496-502
A conditioned taste aversion (CTA) procedure in mice was used to investigate the stimulus effects of the serotonin reuptake inhibitors (SSRIs) fluvoxamine and fluoxetine. Fluvoxamine elicited a reliable CTA (ED50 = 24 mg/kg, SC) and a number of drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5453f12acc61b633cebb1c5564bd03f
https://doi.org/10.1007/s002130050794
https://doi.org/10.1007/s002130050794
Publikováno v:
Psychopharmacology. 116:523-528
Chronic sequential exposure to a variety of mild unpredictable stressors has previously been found to depress the consumption of a dilute (1%) sucrose solution and to inhibit food-induced place preference conditioning. In the present study, using a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebfd5e2530dac801a37c18a1d0b6d83
https://doi.org/10.1007/bf02247488
https://doi.org/10.1007/bf02247488
Publikováno v:
European Journal of Pharmacology. 263:315-318
Induction of lower lip retraction after local infusion of the selective 5-HT1A receptor agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in the dorsal and median raphe nuclei was measured. Infusion of 8-OH-DPAT (2.5, 5 and 10 microgra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00af8f9caf9c6db7d92c30027f7fe205
https://doi.org/10.1016/0014-2999(94)90728-5
https://doi.org/10.1016/0014-2999(94)90728-5
Publikováno v:
Psychopharmacology. 112:437-444
The effect of chronic administration of trifluoperazine on the perioral movement profile of Wistar and Sprague-Dawley rats was examined. Perioral movements were characterised by visual observations, coupled with electromyographic recording from the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447e6645f48ce6f6f94d78118063eb72
https://doi.org/10.1007/bf02244891
https://doi.org/10.1007/bf02244891
Autor:
Chris L.E. Broekkamp, Pedro H. H. Hermkens, J. M. L. Van Der Werf‐Pieters, T. De Boer, Harry C. J. Ottenheijm, J. W. Van Nispen
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb373cf88315379387a1bd2fbd9ef74
https://doi.org/10.1002/chin.199331279
https://doi.org/10.1002/chin.199331279
Publikováno v:
Behavioral and Neural Biology. 55:214-226
5-hydroxytryptamine (5HT)-depleted rats were subjected to behavioral experiments in which the response to activation of 5HT 1A , 5HT 1c , and 5HT 2 receptor subtypes was measured. Depletion of 5HT was produced by unilateral intracerebroventricular in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dcbd90df503495c5a79d5f82562786
https://doi.org/10.1016/0163-1047(91)80140-a
https://doi.org/10.1016/0163-1047(91)80140-a
Publikováno v:
European Journal of Pharmacology. 187:97-103
Selective activation of the 5-HT1A receptor induces lower lip retraction (LLR) in rats. 8-Hydroxy-dipropylamino tetralin (8-OH-DPAT)-induced LLR could not be antagonised by the 5-HT antagonists methysergide, metergoline or mesulergine. In fact, some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d32ec2e7682044eb6b6dc6d920ead4
https://doi.org/10.1016/0014-2999(90)90344-6
https://doi.org/10.1016/0014-2999(90)90344-6
Publikováno v:
European Journal of Pharmacology. 177:201-204
The selective serotonin (5-HT) uptake inhibitors fluvoxamine and sertraline had anti-aversive effects when administered acutely. Imipramine and clomipramine, which combine noradrenaline (NA) and 5-HT uptake blocking properties, did not have significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb11f2414ff1b036c9e6b1af223b6ef3
https://doi.org/10.1016/0014-2999(90)90271-7
https://doi.org/10.1016/0014-2999(90)90271-7