Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chris Kingsley"'
Autor:
Brendan D Looyenga, Danielle Hutchings, Irene Cherni, Chris Kingsley, Glen J Weiss, Jeffrey P Mackeigan
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30820 (2012)
Constitutive activation of STAT3 is a common feature in many solid tumors including non-small cell lung carcinoma (NSCLC). While activation of STAT3 is commonly achieved by somatic mutations to JAK2 in hematologic malignancies, similar mutations are
Externí odkaz:
https://doaj.org/article/77efa532dc6343d789f76b66d67c4171
Autor:
Lance B Price, Cindy M Liu, Johan H Melendez, Yelena M Frankel, David Engelthaler, Maliha Aziz, Jolene Bowers, Rogan Rattray, Jacques Ravel, Chris Kingsley, Paul S Keim, Gerald S Lazarus, Jonathan M Zenilman
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6462 (2009)
BackgroundBacterial colonization is hypothesized to play a pathogenic role in the non-healing state of chronic wounds. We characterized wound bacteria from a cohort of chronic wound patients using a 16S rRNA gene-based pyrosequencing approach and ass
Externí odkaz:
https://doaj.org/article/1ffe18b194f74ecf9103a1faefa29437
Publikováno v:
Cancer Letters. 338:239-248
Insulin receptor substrate (IRS) proteins have been shown to play an important role in breast cancer by differentially regulating cancer cell survival, proliferation, and motility. Furthermore, the IL-4-induced tyrosine phosphorylation of the transcr
Publikováno v:
Journal of Thoracic Oncology. 4:1313-1321
Introduction With low 5-year survival rates and little progress in therapy, improvements in therapeutic strategies for the treatment of small cell lung cancer (SCLC) and large cell lung cancer (LCC) are warranted. We hypothesized that different SCLC
Autor:
Louise Warburton, Livio Heath, Anna-Lise Williamson, Chris Kingsley, M.R. Perrin, William Horsfield, Darren P. Martin, Edward P. Rybicki
Publikováno v:
Journal of Virology. 78:9277-9284
Psittacine beak and feather disease (PBFD), caused by Beak and feather disease virus (BFDV), is the most significant infectious disease in psittacines. PBFD is thought to have originated in Australia but is now found worldwide; in Africa, it threaten
Autor:
Henry R. Bourne, René Onrust, Paul Herzmark, Patty P. Chi, Chris Kingsley, Pablo Garcia, Olivier Lichtarge
Publikováno v:
Science. 275:381-384
Transmembrane receptors for hormones, neurotransmitters, light, and odorants mediate their cellular effects by activating heterotrimeric guanine nucleotide-binding proteins (G proteins). Crystal structures have revealed contact surfaces between G pro
Autor:
Danielle Hutchings, Glen J. Weiss, Jeffrey P. MacKeigan, Chris Kingsley, Irene Cherni, Brendan D. Looyenga
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 2, p e30820 (2012)
PLoS ONE, Vol 7, Iss 2, p e30820 (2012)
Constitutive activation of STAT3 is a common feature in many solid tumors including non-small cell lung carcinoma (NSCLC). While activation of STAT3 is commonly achieved by somatic mutations to JAK2 in hematologic malignancies, similar mutations are
Autor:
Shilpi Arora, Irene Cherni, Guy M. Raz, Carlos D. Lorenzo, Galen Hostetter, Kristi Allen, Chris Kingsley, Glen J. Weiss, Shravan Sridhar, Aprill Watanabe, David K. Edwards
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 76(2)
Introduction The Hedgehog Signaling Pathway (HHSP) has been implicated in the development of multiple cancers. HHSP activation may primarily be hedgehog ligand-dependent in non-small cell lung cancer (NSCLC); while a subset may be ligand-independent.
Publikováno v:
ISQED
FPGAs are a great platform for studying within-die process variation because test structures can be implemented in product silicon using reconfigurable logic. This approach can achieve very high coverage without wasting otherwise useful silicon area.
Autor:
Chris Kingsley, Astar Winoto
Publikováno v:
Molecular and Cellular Biology. 12:4251-4261