Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Chris Kiani"'
Autor:
Ren-Ke Li, Manjula Maganti, Tamotsu Yasuda, Donald A.G. Mickle, Chris Kiani, Richard D. Weisel
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 129(4):904-911
BackgroundCell transplantation improves heart function after myocardial infarction. This study investigated the survival of implanted cells in normal and infarcted myocardium.MethodsMale rat aortic smooth muscle cells were cultured. For the in vitro
Autor:
Chris Kiani, Yaojiong Wu, Daniel Y. Lee, Jin Wu, Yaou Zhang, Liu Cao, Albert Yee, Burton B. Yang
Publikováno v:
Matrix Biology. 24:3-13
Oxidant injury plays a critical role in the degenerative changes that are characterized by a decline in parenchymal cell numbers and viability, and occur with aging and in the etiology of many diseases. The extracellular proteoglycan versican is wide
Autor:
Lee Cyn Ang, Yaou Zhang, Chris Kiani, Mark E. Adams, Liwen Chen, Vivian Lee, Peng-Sheng Zheng, Yaojiong Wu, Frouz F. Paiwand, Liu Cao, Burton B. Yang
Publikováno v:
Journal of Biological Chemistry. 276:14178-14186
This study was designed to investigate the mechanisms by which mutant versican constructs play a dominant-negative effect on astrocytoma cell proliferation. Although a mini-versican or a versican G3 construct promoted growth of U87 astrocytoma cells,
Autor:
Chris KIANI, Vivian LEE, Liu CAO, Liwen CHEN, Yaojiong WU, Yaou ZHANG, Mark E. ADAMS, Burton B. YANG
Publikováno v:
Biochemical Journal. 354:199-207
Aggrecan is a member of the chondroitin sulphate (CS) proteoglycan family, which also includes versican/PG-M, neurocan and brevican. Members of this family exhibit structural similarity: a G1 domain at the N-terminus and a G3 domain at the C-terminus
Autor:
Chris Kiani, Burton B. Yang, Yaou Zhang, Yeqi Yao, Liu Cao, Zhaosheng Lin, Vivian Lee, David Spaner, Mark E. Adams
Publikováno v:
Journal of Cellular Biochemistry. 77:569-583
Most squamous epithelial cells are strictly anchorage-dependent cell types. We observed that epidermal growth factor (EGF) promoted the growth of A431 squamous carcinoma cells in suspension cultures but suppressed cell growth and induced apoptosis in
Publikováno v:
Journal of Cellular Biochemistry. 79:322-333
The most abundant macromolecules in cartilage are hyaluronan, collagen, aggrecan, and link protein, which are believed to play roles in maintaining a unique three-dimensional network for a functional joint. This study was designed to investigate the
Publikováno v:
Matrix Biology. 18:343-355
We have observed that the spent culture media in suspended chondrocyte cultures is essential for the survival of the cells, since complete change of the spent media induces severe programmed cell death (apoptosis). Moreover, we showed that extracellu
Publikováno v:
Journal of Cellular Biochemistry. 73:445-457
We have previously demonstrated that versican stimulated NIH3T3 fibroblast proliferation. Since versican is expressed in cartilage, we investigated whether versican plays a role in chondrocyte proliferation. We developed a technique to stably express
Publikováno v:
Circulation. 112
Background— After a myocardial infarction, the injured region becomes fibrotic and the myocardial scar may expand if the ventricular wall lacks elasticity. Cardiac dilatation may precipitate the vicious cycle of progressive heart failure. The prese
Autor:
Yaojiong Wu, Burton B. Yang, Jianping Wen, Wang Sheng, Liwen Chen, Liu Cao, Chris Kiani, Peng-Sheng Zheng, Mark E. Adams, Vivian Lee
Publikováno v:
Biochemistry. 42(23)
Members of the large aggregating chondroitin sulfate proteoglycans are characterized by an N-terminal fragment known as Gl domain, which is composed of an immunoglobulin (IgG)-like motif and two tandem repeats (TR). Previous studies have indicated th