Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Chris Karlovich"'
Autor:
Erin R. Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N. Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P. Mickey Williams, Chris Karlovich, Amanda Peach, D’andra Howell, James Doroshow, Lindsay Kilburn, Roger J. Packer, Sabine Mueller, Javad Nazarian
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-6 (2022)
Abstract Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to the sensitive tumor location. We developed a targeted deep sequencing platform to detect tumor driver mutat
Externí odkaz:
https://doaj.org/article/9e314be8330c4153b226c12c059956f7
Autor:
Yingdong Zhao, Ming-Chung Li, Mariam M. Konaté, Li Chen, Biswajit Das, Chris Karlovich, P. Mickey Williams, Yvonne A. Evrard, James H. Doroshow, Lisa M. McShane
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background In order to correctly decode phenotypic information from RNA-sequencing (RNA-seq) data, careful selection of the RNA-seq quantification measure is critical for inter-sample comparisons and for downstream analyses, such as differen
Externí odkaz:
https://doaj.org/article/c10f445a336e4544bc1017e110c062d5
Autor:
Johan K. Skog, Luis E. Raez, Bakhos A. Tannous, Jihane Tannous, Mikkel Noerholm, Anne Krug, Mitch Raponi, Chris Karlovich, Raajdeep Venkatesan, Mia Sher, Patricia L. Neal, John Healy, James Hurley, Vasisht Tadigotla, Dominik G. Grimm, Elena Castellanos-Rizaldos
Supplementary Table 1. Clinical characteristics of patients included in the study (T790M positive/negative and the different pools of plasma from healthy donors); Supplementary Table 2. Mutant admixtures used as part of the analytical validation. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d1407b8d77a4c25a925242e7b889a1
https://doi.org/10.1158/1078-0432.22469558.v1
https://doi.org/10.1158/1078-0432.22469558.v1
Autor:
Heather Wakelee, Keunchil Park, Andrew R. Allen, Mitch Raponi, Lindsey Rolfe, Darrin Despain, Shannon Matheny, Patrick O'Donnell, Sean Chien, Lin Wu, Cloud Paweletz, Shirish Gadgeel, D. Ross Camidge, Benjamin Solomon, Jean-Charles Soria, David Spigel, Leora Horn, Philipp Angenendt, Wei Wen, Krzysztof Konopa, Lecia V. Sequist, Elaina Mann, Jong-Mu Sun, Jonathan W. Goldman, Chris Karlovich
Supplementary Tables S1-7. Supplementary Table S1. Clinical characteristics of patients in the present analysis. Supplementary Table S2. Plasma/tissue concordance results for del19 and L858R mutations. Supplementary Table S3. EGFR mutations identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3dc6a18c5e310afed59143a08002fc
https://doi.org/10.1158/1078-0432.22458872.v1
https://doi.org/10.1158/1078-0432.22458872.v1
Autor:
Heather Wakelee, Keunchil Park, Andrew R. Allen, Mitch Raponi, Lindsey Rolfe, Darrin Despain, Shannon Matheny, Patrick O'Donnell, Sean Chien, Lin Wu, Cloud Paweletz, Shirish Gadgeel, D. Ross Camidge, Benjamin Solomon, Jean-Charles Soria, David Spigel, Leora Horn, Philipp Angenendt, Wei Wen, Krzysztof Konopa, Lecia V. Sequist, Elaina Mann, Jong-Mu Sun, Jonathan W. Goldman, Chris Karlovich
Purpose: The evaluation of plasma testing for the EGFR resistance mutation T790M in NSCLC patients has not been broadly explored. We investigated the detection of EGFR activating and T790M mutations in matched tumor tissue and plasma, mostly from pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe1cc876e37080c39de4bc75b79f3ae
https://doi.org/10.1158/1078-0432.c.6524060.v1
https://doi.org/10.1158/1078-0432.c.6524060.v1
Autor:
Johan K. Skog, Luis E. Raez, Bakhos A. Tannous, Jihane Tannous, Mikkel Noerholm, Anne Krug, Mitch Raponi, Chris Karlovich, Raajdeep Venkatesan, Mia Sher, Patricia L. Neal, John Healy, James Hurley, Vasisht Tadigotla, Dominik G. Grimm, Elena Castellanos-Rizaldos
Purpose: About 60% of non–small cell lung cancer (NSCLC) patients develop resistance to targeted epidermal growth factor receptor (EGFR) inhibitor therapy through the EGFR T790M mutation. Patients with this mutation respond well to third-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd7c2b5696d5c2befad5d9c0e112d25
https://doi.org/10.1158/1078-0432.c.6527291.v1
https://doi.org/10.1158/1078-0432.c.6527291.v1
PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components
Autor:
Geraldine, O'Sullivan Coyne, Chris, Karlovich, Deborah, Wilsker, Andrea Regier, Voth, Ralph E, Parchment, Alice P, Chen, James H, Doroshow
Publikováno v:
OncoTargets and Therapy. 15:165-180
Poly(ADP-ribose) polymerase inhibitors (PARPi) have been in clinical use since 2014 for certain patients with germline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69677cfe42a1e4dd7c4b1c2b6b84f11a
https://doi.org/10.2147/ott.s278092
https://doi.org/10.2147/ott.s278092
Autor:
Robert T. McCormack, Daniel Stetson, Dana E. Connors, J. Carl Barrett, Kenneth D. Cole, Steven P. Lund, Chris Karlovich, Thomas Forbes, P. Mickey Williams, Megan H. Cleveland, Laura M. Yee, Christie J. Lau, Cloud P. Paweletz, Gary J. Kelloff, Benoit Destenaves, Hua-Jun He, Susan M. Keating
Publikováno v:
JCO Precision Oncology
PURPOSEWe report the results from a Foundation for the National Institutes of Health Biomarkers Consortium project to address the absence of well-validated quality control materials (QCMs) for circulating tumor DNA (ctDNA) testing. This absence is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65932e30bc1310e4e98453053f022f10
https://doi.org/10.1200/po.20.00528
https://doi.org/10.1200/po.20.00528
Autor:
Yvonne A. Evrard, Li Chen, Sergio Alcoser, Gareth Bliss, Carrie Bonomi, Suzanne Borgel, John Carter, Ting-Chia Chang, Alice Chen, Kevin Cooper, Biswajit Das, Kelly Dougherty, Lindsay Dutko, Marion Gibson, Michelle M. Ahalt-Gottholm, Tara Grinnage-Pulley, Keegan Kalmbach, Chris Karlovich, Kimberly Klarmann, Shahanawaz Jiwani, Tiffanie Miner, Michael Mullendore, Matthew Murphy, Kevin Plater, Gloryvee Rivera, Jessica Steed, Luke Stockwin, Cindy R. Timme, Dianne L. Newton, Paul Mickey Williams, Melinda G. Hollingshead, James H. Doroshow
Publikováno v:
Cancer Research. 83:40-40
The National Cancer Institute’s Patient-Derived Models Repository (NCI PDMR; https://pdmr.cancer.gov) has developed a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), in vitro patient-derived tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25aae7a2accaeeccf1f08fe1ac771308
https://doi.org/10.1158/1538-7445.am2023-40
https://doi.org/10.1158/1538-7445.am2023-40
Autor:
Junko Tsuji, Jin Wang, David Cohen, Jianjun Zhang, Jijun Yu, Ignacio I. Wistuba, Tomas Vilimas, Len Taing, Li Chen, Chunhua Yan, Qing-Rong Chen, Magdalena Thurin, Rebecca A. Enos, Xiaoman Wang, Peng Jiang, Candace Patterson, Mohamed Uduman, Catherine J. Wu, Beatriz Sanchez-Espiridion, Aashna Jhaveri, Yang Liu, Andrew Futreal, Jingxin Fu, Jiexin Zhang, Jack Lee, Donna Neuberg, Curtis Gumbs, Xin Huang, Sylvie Janssens, Collin Tokheim, Zexian Zeng, Avinash Das Sahu, Ming Tang, Carrie Cibulskis, James Lindsay, Cu Nguyen, Jason L. Weirather, Joyce Yu, Stacey Gabriel, Ethan Cerami, Dzifa Y. Duose, Daoud Meerzaman, Chris Karlovich, Sharmistha Sarkar, X. Shirley Liu, Biswajit Das, Sachet A. Shukla, Jianhua Zhang
Publikováno v:
Clin Cancer Res
Purpose: Whole-exome (WES) and RNA sequencing (RNA-seq) are key components of cancer immunogenomic analyses. To evaluate the consistency of tumor WES and RNA-seq profiling platforms across different centers, the Cancer Immune Monitoring and Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaabc18bd833d97fd6b4f25c896ff85
https://doi.org/10.1158/1078-0432.ccr-20-3251
https://doi.org/10.1158/1078-0432.ccr-20-3251