Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Chris Ka-Fai Li"'
Autor:
Erio Barale-Thomas, Ren Zhu, Qing Lu, Chris Ka-fai Li, Qinglin Han, Tse-I. Lin, Sandra De Jonghe, An De Creus, Florence Herschke, Qun Wu
Publikováno v:
Antiviral research. 196
JNJ-64794964 (JNJ-4964/AL-034/TQ-A3334), an oral toll-like receptor 7 agonist, is being investigated for the treatment of chronic hepatitis B (CHB), a condition with a high unmet medical need. The anti–hepatitis B (HBV) activity of JNJ-4964 was ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b812bebfc1bb12de044893698a586a
https://pubmed.ncbi.nlm.nih.gov/34718044
https://pubmed.ncbi.nlm.nih.gov/34718044
Autor:
Laura Denney, Celia Aitken, Chris Ka-Fai Li, Eleri Wilson-Davies, Wai Ling Kok, Colin Clelland, Kevin Rooney, Duncan Young, Tao Dong, Andrew J McMichael, William F Carman, Ling-Pei Ho
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10675 (2010)
BACKGROUND:The cause of severe disease in some patients infected with pandemic influenza A virus is unclear. METHODOLOGY/PRINCIPAL FINDINGS:We present the cellular immunology profile in the blood, and detailed clinical (and post-mortem) findings of t
Externí odkaz:
https://doaj.org/article/0a1e1fdc702d44d4a38fb4cd857c0ecc
Autor:
Rongbao Gao, Libo Dong, Jie Dong, Leying Wen, Ye Zhang, Hongjie Yu, Zijian Feng, Minmei Chen, Yi Tan, Zhaojun Mo, Haiyan Liu, Yunyan Fan, Kunxiong Li, Chris Ka-Fai Li, Dexin Li, Weizhong Yang, Yuelong Shu
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13315 (2010)
Autopsy studies have shown that human highly pathogenic avian influenza virus (H5N1) can infect multiple human organs other than just the lungs, and that possible causes of organ damage are either viral replication and/or dysregulation of cytokines a
Externí odkaz:
https://doaj.org/article/e670ccb5d7684d4b897736259a9366c0
Publikováno v:
Journal of Hepatology. 70:e49-e50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f96b14e3cab53e9c315ffa124465996
https://doi.org/10.1016/s0618-8278(19)30088-x
https://doi.org/10.1016/s0618-8278(19)30088-x
Autor:
Leigh Anne Eller, Hannah Kibuuka, Marcus Buggert, Barton F. Haynes, Nicole F. Bernard, Korey Demers, Nilu Goonetilleke, Sarah J. Ratcliffe, Chris Ka-fai Li, Sorachai Nitayaphan, Lucas Maganga, George Makedonas, Mark K. Slifka, Jean-Pierre Routy, Merlin L. Robb, Michael R. Betts, Andrew J. McMichael, Michael A. Eller, Kathleen Rono
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 8, p e1005805 (2016)
PLoS Pathogens, Vol 12, Iss 8, p e1005805 (2016)
The loss of HIV-specific CD8+ T cell cytolytic function is a primary factor underlying progressive HIV infection, but whether HIV-specific CD8+ T cells initially possess cytolytic effector capacity, and when and why this may be lost during infection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655a17018deb64b1666a9f2ba8b5c5f3
http://europepmc.org/articles/PMC4972399
http://europepmc.org/articles/PMC4972399
Autor:
Dan Feng, Yong Hong Ma, Jan Hendrik Richardus, Xiao-Ning Xu, Na Jia, Wu-Chun Cao, Chris Ka-fai Li, Hong Yang, Rong Dang, Yun Xiao Liu
Publikováno v:
Journal of Medical Virology, 81(8), 1471-1476. Wiley-Liss Inc.
Influenza epidemic is an important cause of severe illness in the elderly. Age-dependent morbidity of influenza in the elderly is associated with weakened immunity. The baseline age-related memory T cell activity in Chinese persons who are exposed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8912424315e0c8a3b667dc337af8ff96
https://doi.org/10.1002/jmv.21544
https://doi.org/10.1002/jmv.21544
Autor:
Xiao-Ning Xu, Ye Zhang, Ming Wang, Dexin Li, Yuelong Shu, Yu Wang, Jiangfang Zhou, Jie Dong, Qian Liang, Xiao-Ping Dong, Rongbao Gao, Tian Bai, Andrew J. McMichael, Chris Ka-fai Li, Zi Li, Dayan Wang, Libo Dong, Weizhong Yang, Zijian Feng, Hongjie Yu, Le-ying Wen
The human respiratory tract is a major site of avian influenza A(H5N1) infection. However, many humans infected with H5N1 present with gastrointestinal tract symptoms, suggesting that this may also be a target for the virus. In this study, we demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6487fb6a8e0cefdae2ff4d86c3a78b
https://ora.ox.ac.uk/objects/uuid:4d906ebe-3045-494d-a173-981b9716fc54
https://ora.ox.ac.uk/objects/uuid:4d906ebe-3045-494d-a173-981b9716fc54
Autor:
Cecilia Chui, Nicola Smith, Xiao-Ning Xu, Dayan Wang, Yan Gao, Mei Dong, Li-Fei Song, Jiang Wu, Yan Liu, Feng-Ji Luo, Zi Li, Liqi Liu, Jiang-Ting Chen, Xu Wang, Bo Li, Yan Yan, Kuan-Ying Huang, Nian-Min Shi, Xiang Zhong, Chris Ka-fai Li, Andrew J. McMichael, Min Lu, Yuelong Shu, Wenfei Zhu, Jianfang Zhou, Ning Du, Weidong Yin
A randomized clinical trial was conducted to assess whether the immunogenicity of seasonal and pandemic (H1N1/09) influenza vaccines is affected by the order of vaccine administration. 151 healthy adult volunteers were randomized into three groups. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bf85b3934e416bd7e0ca3cb23a44de
https://ora.ox.ac.uk/objects/uuid:30b51797-063e-4adc-a7ed-2421d62ee396
https://ora.ox.ac.uk/objects/uuid:30b51797-063e-4adc-a7ed-2421d62ee396
Autor:
Andrew J. McMichael, Xiao-Ning Xu, Elizabeth A. Clutterbuck, Cecilia Chui, Kuan-Ying A. Huang, Tom Wilkinson, Chris Ka-fai Li, Anthony Gilbert, Tzou Yien Lin, John S. Oxford, Rob Lambkin-Williams
Background Antibodies play a major role in the protection against influenza virus in human. However, the antibody level is usually short-lived and the cellular mechanisms underlying influenza virus-specific antibody response to acute infection remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be2585e9a022b297482c8e6743084d8
https://ora.ox.ac.uk/objects/uuid:29a5770d-55e3-4155-bd72-10d2239d0ec0
https://ora.ox.ac.uk/objects/uuid:29a5770d-55e3-4155-bd72-10d2239d0ec0
Autor:
Xiao-Ai Zhang, Wei Liu, Xiao-Ning Xu, Sake J. de Vlas, Wu-Chun Cao, Tao Jiang, Yigang Tong, Fang Tang, Chris Ka-fai Li, Mai-Juan Ma, Hong Yang, Li-Juan Liu, Cui He, Lei Zhang, Zhong-Tao Xin, Zeng-De Li, Jan Hendrik Richardus, Mao-Ti Wei
Publikováno v:
Clinical Infectious Diseases, 51(9), 1028-1032. Oxford University Press
Background. We followed a cohort of 773 individuals who received a monovalent vaccine against 2009 pandemic influenza A (H1N1). Approximately 6 weeks after vaccination, 12 persons developed the disease. Methods. Three groups of subjects were studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb68fb5cf2ae54b8fabe496eed7cd5b
https://doi.org/10.1086/656588
https://doi.org/10.1086/656588