Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Chris J. van Boxtel"'
Autor:
H. E. Wiersma, Chris J. van Boxtel, Dietmar Trenk, Karin Dilger, Jan A.J.M. Taminiau, Johanna C. Escher, Marc A. Benninga
Publikováno v:
Inflammatory bowel diseases, 10(5), 626-631. John Wiley and Sons Inc.
Inflammatory Bowel Diseases, 10(5), 626-631. Oxford University Press
Inflammatory Bowel Diseases, 10(5), 626-631. Oxford University Press
Mesalazine is a first-line drug in pediatric inflammatory bowel disease (IBD), and is customarily used to induce and maintain remission in mild to moderate disease. In children, pharmacokinetic data are scarce, and dosage recommendations are largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727653c7b5f3eace244f49121256cf4c
https://doi.org/10.1097/00054725-200409000-00019
https://doi.org/10.1097/00054725-200409000-00019
Publikováno v:
Clinical Pharmacology & Therapeutics. 66:408-414
Background Artemether is a new and effective treatment for malaria, although relapse is a problem in monotherapy. These relapses could be related to a time-dependent decline in artemether plasma levels described in multiple-dose studies and probably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0b3ec9658093de139dec9ffd55935c4
https://doi.org/10.1053/cp.1999.v66.a101946
https://doi.org/10.1053/cp.1999.v66.a101946
Publikováno v:
Van Agtmael, M A, Eggelte, T A & Van Boxtel, C J 1999, ' Artemisinin drugs in the treatment of malaria : From medicinal herb to registered medication ', Trends in Pharmacological Sciences, vol. 20, no. 5, pp. 199-205 . https://doi.org/10.1016/S0165-6147(99)01302-4
Registration in Europe of several artemisinin drugs for the treatment of malaria can soon be expected. Artemisinin is isolated from the herb Artemisia annua , in use in China more than 2000 years as a herbal tea against fever. Artemisinin drugs are b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da00e18daf88c69ed323183cdeea098d
http://www.scopus.com/inward/record.url?scp=0033035094&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=0033035094&partnerID=8YFLogxK
Publikováno v:
Therapeutic Drug Monitoring, 20(1), 109-116. Lippincott Williams and Wilkins
Van Agtmael, M A, Butter, J J, Portier, E J G & Van Boxtel, C J 1998, ' Validation of an improved reversed-phase high-performance liquid chromatography assay with reductive electrochemical detection for the determination of artemisinin derivatives in man ', Therapeutic Drug Monitoring, vol. 20, no. 1, pp. 109-116 . https://doi.org/10.1097/00007691-199802000-00020
Van Agtmael, M A, Butter, J J, Portier, E J G & Van Boxtel, C J 1998, ' Validation of an improved reversed-phase high-performance liquid chromatography assay with reductive electrochemical detection for the determination of artemisinin derivatives in man ', Therapeutic Drug Monitoring, vol. 20, no. 1, pp. 109-116 . https://doi.org/10.1097/00007691-199802000-00020
For the determination of artemisinin (ART) and analogs, a reversed- phase high-performance liquid chromatography method using reductive electrochemical detection ED was set up with some important modifications as compared to previously published assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502aebcb8b7874cbdb49e79e04a9897c
https://doi.org/10.1097/00007691-199802000-00020
https://doi.org/10.1097/00007691-199802000-00020
Autor:
Chris J. van Boxtel
Publikováno v:
Pharmacoepidemiology & Drug Safety. 2:S7-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4579f323b684b1ae150074a5d9f594a
https://doi.org/10.1002/pds.2630020703
https://doi.org/10.1002/pds.2630020703
Publikováno v:
Clinical Pharmacology and Therapeutics. 50:16-24
The influence of dosage time of midazolam on its pharmacokinetics and effects on the central nervous system were investigated in six healthy volunteers, with pharmacokinetic-pharmacodynamic modeling. Each volunteer received single oral doses of 15 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1a1f5c951591ec520dcb45e3370b45
https://doi.org/10.1038/clpt.1991.99
https://doi.org/10.1038/clpt.1991.99
Autor:
Chris J. van Boxtel, Piet A. Kager, Tran Khac Dien, Peter J. de Vries, Nguyen Xuan Khanh, Dao Dinh Duc, Richard P. Koopmans
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene, 92(4), 434-436. Elsevier
Eight male Vietnamese malaria patients received 600 mg of artemisinin in a single dose of 3 suppositories containing 200 mg each; 24 h later they received a single oral dose of mefloquine, 15 mg/kg. Plasma artemisinin concentrations were measured unt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf27322e9058680918e3abf12f7202a
https://doi.org/10.1016/s0035-9203(98)91082-3
https://doi.org/10.1016/s0035-9203(98)91082-3
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 25(3-4)
Adrenergic down-regulation can occur rapidly in many tissues. Therefore beta 2-agonists might have a rapidly decreasing effect in time, which is a potential problem for the treatment of bronchial asthma. This in vivo study tested the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6add0c6fc655e56391529d162532c08c
https://pubmed.ncbi.nlm.nih.gov/11420887
https://pubmed.ncbi.nlm.nih.gov/11420887
Autor:
Piet A. Kager, Le Dang Ha, Nguyen Xuan Khanh, Chris J. van Boxtel, Peter J. de Vries, Richard P. Koopmans
Six patients with uncomplicated falciparum malaria received artesunate for 5 days. Plasma concentrations of artesunate and dihydroartemisinin were determined by high-performance liquid chromatography with electrochemical detection. The concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71d47d14d01b79648e461144f1f9d46
https://europepmc.org/articles/PMC89184/
https://europepmc.org/articles/PMC89184/
