Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chris J. de Witte"'
Autor:
Jose Espejo Valle-Inclan, Christina Stangl, Anouk C. de Jong, Lisanne F. van Dessel, Markus J. van Roosmalen, Jean C. A. Helmijr, Ivo Renkens, Roel Janssen, Sam de Blank, Chris J. de Witte, John W. M. Martens, Maurice P. H. M. Jansen, Martijn P. Lolkema, Wigard P. Kloosterman
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Here, we describe a novel approach for rapid discovery of a set of tumor-specific genomic structural variants (SVs), based on a combination of low coverage cancer genome sequencing using Oxford Nanopore with an SV calling and filtering pipel
Externí odkaz:
https://doaj.org/article/dc2d84df5339442da6944319858a489d
Autor:
Chris J. de Witte, Roel Janssen, Wigard P. Kloosterman, Martijn P. Lolkema, Christina Stangl, Markus J. van Roosmalen, Jose Espejo Valle-Inclan, Anouk C. de Jong, Jean C. A. Helmijr, Sam de Blank, Maurice P.H.M. Jansen, Ivo Renkens, John W.M. Martens, Lisanne F. van Dessel
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Genome Medicine
Genome Medicine, 13(1):86. BioMed Central Ltd.
Genome Medicine
Genome Medicine, 13(1):86. BioMed Central Ltd.
Here, we describe a novel approach for rapid discovery of a set of tumor-specific genomic structural variants (SVs), based on a combination of low coverage cancer genome sequencing using Oxford Nanopore with an SV calling and filtering pipeline. We a
Autor:
Wigard P. Kloosterman, Chris J. de Witte, Ronald P. Zweemer, Jose Espejo Valle-Inclan, Nizar Hami, Paul J. van Diest, Kadi Lõhmussaar, Hugo J. Snippert, Edwin Cuppen, Geertruida N. Jonges, Hans Clevers, Oded Kopper, Ellen Stelloo, Petronella O. Witteveen, Celien P.H. Vreuls, Luan Nguyen
Publikováno v:
Cell Reports, 31(11). Cell Press
Cell Reports, Vol 31, Iss 11, Pp 107762-(2020)
Cell Reports, Vol 31, Iss 11, Pp 107762-(2020)
PurposeThere remains an unmet need for preclinical models to enable personalized therapy for ovarian cancer (OC) patients. Recently, patient-derived organoid (PDO) cultures of patients with OC have been established that faithfully represent the histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785c038a130b56348add66ed4117993f
https://pure.knaw.nl/portal/en/publications/4108a9d9-3056-417b-84e1-b29acf44532a
https://pure.knaw.nl/portal/en/publications/4108a9d9-3056-417b-84e1-b29acf44532a
Autor:
Arne Van Hoeck, Chris J. de Witte, Ronald P. Zweemer, Wigard P. Kloosterman, Christa van Schaik van de Mheen, Luan Nguyen, Edwin Cuppen, Petronella O. Witteveen, Marion Stevense, Petronella B. Ottevanger, Joachim Kutzera, Mathilde Jalving, Ingrid A. Boere
Publikováno v:
Cancers, 14(6):1511. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 14(6):1511. MDPI AG
Cancers, 14, 6
Cancers, 14
Cancers; Volume 14; Issue 6; Pages: 1511
Cancers, 14(6):1511. MDPI AG
Cancers, 14, 6
Cancers, 14
Cancers; Volume 14; Issue 6; Pages: 1511
The majority of patients with ovarian cancer ultimately develop recurrent chemotherapy resistant disease. Treatment stratification is mainly based on histological subtype and stage, prior response to platinum-based chemotherapy and time to recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2643941057090a8cc91bb95a96757502
https://doi.org/10.1101/2020.06.04.20118976
https://doi.org/10.1101/2020.06.04.20118976
Autor:
Martijn P. Lolkema, Maurice P.H.M. Jansen, Christina Stangl, Wigard P. Kloosterman, Jean C. A. Helmijr, Ivo Renkens, Markus J. van Roosmalen, Lisanne F. van Dessel, Anouk C. de Jong, John W.M. Martens, Sam de Blank, Jose Espejo Valle-Inclan, Chris J. de Witte
Somatic genomic structural variations (SVs) are promising personalized biomarkers for sensitive and specific detection of circulating tumor DNA (ctDNA) in liquid biopsies. However, affordable and fast identification of such SV biomarkers is challengi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2d249cec9ba1c04d210754386d6638
https://doi.org/10.1101/19011932
https://doi.org/10.1101/19011932
Autor:
Jose Espejo Valle-Inclan, Victor W.H. Ho, Nizar Hami, Markus J. van Roosmalen, Benjamin G. Neel, Kadi Lõhmussaar, Anjali Vanita Balgobind, Lennart Kester, Ronald P. Zweemer, Harry Begthel, Harry Vrieling, Jeroen Korving, Tjalling Bosse, Chris J. de Witte, Maaike P.G. Vreeswijk, Oded Kopper, Wigard P. Kloosterman, Natalie Proost, Alexander van Oudenaarden, Marieke van de Ven, Paul J. van Diest, Rebecca Theeuwsen, Bas Ponsioen, Johannes L. Bos, Hugo J. Snippert, Katja N. Gaarenstroom, Lise M van Wijk, Trudy N. Jonges, Hans Clevers, Petronella O. Witteveen, Sonia Aristín Revilla
Publikováno v:
Nature Medicine, 25(5), 838-849. Nature Publishing Group
Nature Medicine, 25(5), 838. Nature Publishing Group
Nature Medicine, 25(5), 838-+. NATURE PUBLISHING GROUP
Nature Medicine, 25(5), 838. Nature Publishing Group
Nature Medicine, 25(5), 838-+. NATURE PUBLISHING GROUP
Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of OC are limited and hard to establish. We present a protocol that enables e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628ba460dc571b7d280acb944303af20
https://pure.knaw.nl/portal/en/publications/45c50205-416f-43d2-984d-0d6a6541c128
https://pure.knaw.nl/portal/en/publications/45c50205-416f-43d2-984d-0d6a6541c128
Autor:
Esther C. J. Consten, Paul M. Verheijen, Egbert Lenters, Steven E. Schraffordt Koops, Jan J. van Iersel, Ivo A. M. J. Broeders, Chris J de Witte
Publikováno v:
Diseases of the colon and rectum. 59(10)
Pelvic floor disorders are a major public health issue. For female genital prolapse, sacrocolpopexy is the gold standard. Laparoscopic ventral mesh rectopexy is a relatively new and promising technique correcting rectal prolapse. There is no literatu