Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chris J. Tinsley"'
Autor:
Joshua R. D. Pearson, Stefania Cuzzubbo, Simon McArthur, Lindy G. Durrant, Jason Adhikaree, Chris J. Tinsley, A. Graham Pockley, Stephanie E. B. McArdle
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Glioblastoma multiforme (GBM) is the most frequently occurring primary brain tumor and has a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or more after diagnosis. Despite aggressive multimodal therapy, consis
Externí odkaz:
https://doaj.org/article/6a7407adfcab4c87aab9894173687565
Autor:
Chris J. Tinsley, Maria Vincent, John Patrick Aggleton, Nadine S Fontaine-Palmer, Malcolm W. Brown, Emma P E Endean, E. Clea Warburton
Publikováno v:
Tinsley, C J, Fontaine-Palmer, N S, Vincent, M, Endean, E P E, Aggleton, J P, Brown, M W & Warburton, E C 2011, ' Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex ', Learning and Memory, vol. 18, pp. 484-492 . https://doi.org/10.1101/lm.2274911
The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into t
Publikováno v:
Hippocampus. 22:466-476
The role of the CAMKK pathway in object recognition memory was investigated. Rats’ performance in a preferential object recognition test was examined after local infusion into the perirhinal cortex of the CAMKK inhibitor STO-609. STO-609 infused ei
Autor:
Chris J. Tinsley
Publikováno v:
Biosystems. 92:159-167
This article explores the theoretical basis of coding within topographic representations, where neurons encoding specific features such as locations, are arranged into maps. A novel type of representation, termed non-specific, where each neuron does
Autor:
Chris J. Tinsley, E. Ellen Billett, Stacey A. Bedwell, Danielle M. MacDonald, Jonathan J. Crofts
Publikováno v:
Frontiers in Systems Neuroscience, Vol 9 (2015)
Frontiers in Systems Neuroscience
Frontiers in Systems Neuroscience
Understanding the structural organization of the prefrontal cortex (PFC) is an important step toward determining its functional organization. Here we investigated the organization of PFC using different neuronal tracers. We injected retrograde (Fluor
Autor:
Nick E. Barraclough, Ben S. Webb, Christopher J. Vincent, Chris J. Tinsley, Andrew M. Derrington
Publikováno v:
Visual Neuroscience. 23:815-824
We measured the responses of single neurons in marmoset visual cortex (V1, V2, and the third visual complex) to moving first-order stimuli and to combined first- and second-order stimuli in order to determine whether first-order motion processing was
Autor:
Andrew M. Derrington, Amanda Parker, Christopher J. Vincent, Ben S. Webb, Nick E. Barraclough, Chris J. Tinsley
Publikováno v:
Journal of Neurophysiology. 90:930-937
A plaid pattern is formed when two sinusoidal gratings of different orientations are added together. Previous work has shown that V1 neurons selectively encode the direction and orientation of the component gratings in a moving plaid but not the dire
Autor:
Chris J. Tinsley, Andrew M. Derrington, Alexander Easton, Amanda Parker, Ben S. Webb, Nick E. Barraclough
Publikováno v:
Visual Neuroscience. 19:583-592
It is well established that the responses of neurons in the lateral geniculate nucleus (LGN) can be modulated by feedback from visual cortex, but it is still unclear how cortico-geniculate afferents regulate the flow of visual information to the cort
Autor:
Amanda Parker, Ben S. Webb, G. R. Goodson, Kris S. Parker, Andrew M. Derrington, Nick E. Barraclough, Alexander Easton, Chris J. Tinsley
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 357:975-985
Colour and greyscale (black and white) pictures look different to us, but it is not clear whether the difference in appearance is a consequence of the way our visual system uses colour signals or a by–product of our experience. In principle, colour
Publikováno v:
Experimental Neurology. 168:88-95
Stereological methods were employed to investigate a novel spontaneously occurring brain mutation in an inbred colony of Wistar rats. These mutants displayed changes (enlarged cerebral ventricles and malformed hippocampi) similar to those seen in H-T