Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chris J. Cadman"'
Publikováno v:
Radiology. 291:814-818
History A 1-year-old boy was referred for cochlear implant assessment after he received a diagnosis of bilateral profound sensorineural hearing loss at neonatal hearing screening shortly after birth. The child was born at term via uneventful delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9c5b9fa4aaf96079bb098125b7b7c3
https://doi.org/10.1148/radiol.2018162304
https://doi.org/10.1148/radiol.2018162304
Publikováno v:
Radiology. 290(2)
History A 1-year-old boy was referred for cochlear implant assessment after he received a diagnosis of bilateral profound sensorineural hearing loss at neonatal hearing screening shortly after birth. The child was born at term via uneventful delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d8046150571cf7bbed00f202d0da85
https://pubmed.ncbi.nlm.nih.gov/30673499
https://pubmed.ncbi.nlm.nih.gov/30673499
Autor:
John Atkinson, Chris J. Cadman, Christian J. Rudolph, Ingeborg van Knippenberg, Emma J. Gwynn, Milind Kumar Gupta, Peter B. Moon, Peter McGlynn, Colin P. Guy, Mark S. Dillingham, Akeel A. Mahdi, Robert G. Lloyd
Publikováno v:
Molecular Cell
Summary Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by helicases with the ability to displace t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f47cecac1c4078714650e413413d21
https://doi.org/10.1016/j.molcel.2009.11.009
https://doi.org/10.1016/j.molcel.2009.11.009
Publikováno v:
Journal of Biological Chemistry. 284:9612-9623
Helicases play critical roles in all aspects of nucleic acid metabolism by catalyzing the remodeling of DNA and RNA structures. UvrD is an abundant helicase in Escherichia coli with well characterized functions in mismatch and nucleotide excision rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e894aed7b55d973f7cd6b4ece232b2
https://doi.org/10.1074/jbc.m808030200
https://doi.org/10.1074/jbc.m808030200
Publikováno v:
Journal of Molecular Biology. 362:18-25
Many studies have demonstrated the need for processing of blocked replication forks to underpin genome duplication. UvrD helicase in Escherichia coli has been implicated in the processing of damaged replication forks, or the recombination intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddbd6606fdb6cb73b77d480e9aa81bb
https://doi.org/10.1016/j.jmb.2006.06.032
https://doi.org/10.1016/j.jmb.2006.06.032
Publikováno v:
Journal of Biological Chemistry. 280:39693-39700
The frequency with which replication forks break down in all organisms requires that specific mechanisms ensure completion of genome duplication. In Escherichia coli a major pathway for reloading of the replicative apparatus at sites of fork breakdow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f4c999d563f9bc9bcbf25699011ad4
https://doi.org/10.1074/jbc.m508521200
https://doi.org/10.1074/jbc.m508521200
Autor:
Chris J. Cadman, Peter McGlynn
Publikováno v:
Nucleic Acids Research. 32:6378-6387
PriA helicase is the major DNA replication restart initiator in Escherichia coli and acts to reload the replicative helicase DnaB back onto the chromosome at repaired replication forks and D-loops formed by recombination. We have discovered that PriA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1b7ff7b23dcc2f5c4c9b1c9a0b0b67
https://doi.org/10.1093/nar/gkh980
https://doi.org/10.1093/nar/gkh980
Autor:
Chris J. Cadman, Peter P. Toth
Publikováno v:
Journal of clinical lipidology. 1(3)
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) are the first-line treatment for dyslipidemia and the results of large statin trials have a significant impact on guidelines for cardiovascular disease (CVD) management, such as tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e112e833284adf242a5f5aba80687c99
https://pubmed.ncbi.nlm.nih.gov/21291679
https://pubmed.ncbi.nlm.nih.gov/21291679