Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Chris J Watson"'
Autor:
Dermot M Wildes, Master Chisale, Richard J Drew, Peter Harrington, Chris J Watson, Mark T Ledwidge, Joe Gallagher
Publikováno v:
EClinicalMedicine, Vol 41, Iss , Pp 101164- (2021)
Background: Our goal was to identify existing clinical prediction rules for predicting hospitalisation due to lower respiratory tract infection (LRTI) in children in primary care, guiding antibiotic therapy. A validation of these rules was then perfo
Externí odkaz:
https://doaj.org/article/b08f6c9caaa44243b315feedeb08c254
Autor:
W H Wilson Tang, Deborah H Kwon, Brian Griffin, Saqer Alkharabsheh, Chris J Watson, Feixiong Cheng, Muzna Hussain, Rabel Misbah, Eoin Donnellan, Yuan Hou, Michael Crookshanks, Andrew J Toth, Penny Houghtaling, Rohit Moudgil, G Thomas Budd, Wael Jaber, Mohamad Kanj, Patrick Collier
Publikováno v:
Open Heart, Vol 7, Iss 2 (2020)
Objectives To investigate timing and age distribution of atrial fibrillation (AF) in selected oncology patients, and the impact of AF timing, CHA2DS2-VASc score and cancer therapeutics on mortality.Methods This is a retrospective cohort study of onco
Externí odkaz:
https://doaj.org/article/3949e658feab4d7786c5605d67026ae1
Autor:
Claire Tonry, Katie Linden, Patrick Collier, Mark Ledwidge, Ken McDonald, Ben C. Collins, Chris J. Watson
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1712 (2024)
Hypertrophic cardiomyopathy (HCM) is a disease, which is difficult to diagnose at an early stage and for which there is a pressing need for more effective treatment options. The purpose of this study was to compare the molecular profile of HCM to tha
Externí odkaz:
https://doaj.org/article/d941efe8c8a94513aed6aa45230a16ab
Autor:
Adam Russell-Hallinan, Oisín Cappa, Lauren Kerrigan, Claire Tonry, Kevin Edgar, Nadezhda Glezeva, Mark Ledwidge, Kenneth McDonald, Patrick Collier, David A. Simpson, Chris J. Watson
Publikováno v:
Cells, Vol 13, Iss 9, p 752 (2024)
Dilated cardiomyopathy (DCM) is the most common cause of heart failure, with a complex aetiology involving multiple cell types. We aimed to detect cell-specific transcriptomic alterations in DCM through analysis that leveraged recent advancements in
Externí odkaz:
https://doaj.org/article/a7cf370415494e2eb326d5f7bf4fe291
Autor:
Shun Hay Pun, Karla M. O’Neill, Kevin S. Edgar, Eleanor K. Gill, Arya Moez, Hojjat Naderi-Meshkin, Sudhir B. Malla, Michelle B. Hookham, Mohammed Alsaggaf, Vinuthna Vani Madishetti, Bianca Botezatu, William King, Coy Brunssen, Henning Morawietz, Philip D. Dunne, Derek P. Brazil, Reinhold J. Medina, Chris J. Watson, David J. Grieve
Publikováno v:
Cells, Vol 12, Iss 18, p 2220 (2023)
Ischaemic cardiovascular disease is associated with tissue hypoxia as a significant determinant of angiogenic dysfunction and adverse remodelling. While cord blood-derived endothelial colony-forming cells (CB-ECFCs) hold clear therapeutic potential d
Externí odkaz:
https://doaj.org/article/c401b027209144cda01f2bdf818f87be
Autor:
Aidonis Rammos, Aris Bechlioulis, Petros Kalogeras, Chris J. Watson, Pietro Salvo, Tommaso Lomonaco, Olga Kardakari, Evanthia E. Tripoliti, Yorgos Goletsis, Dimitris I. Fotiadis, Christos S. Katsouras, Lampros K. Michalis, Katerina K. Naka
Publikováno v:
Life, Vol 13, Iss 9, p 1818 (2023)
Background: Serum natriuretic peptides (NPs) have an established role in heart failure (HF) diagnosis. Saliva NT-proBNP that may be easily acquired has been studied little. Methods: Ninety-nine subjects were enrolled; thirty-six obese or hypertensive
Externí odkaz:
https://doaj.org/article/c28a4aae7c40425b99afaf3f4df84d12
Autor:
Claire Sweeney, Rebabonye B. Pharithi, Brian Kerr, Cristin Ryan, Fiona Ryan, Líbhan Collins, Carmel Halley, Matt Barrett, Chris J. Watson, Kenneth McDonald, Mark Ledwidge
Publikováno v:
ESC Heart Failure, Vol 8, Iss 6, Pp 5081-5091 (2021)
Abstract Aims Guidelines support the role of B‐type natriuretic peptide (BNP) and amino‐terminal pro‐BNP (NT‐proBNP) for risk stratification of patients in programmes to prevent heart failure (HF). Although biologically formed in a 1:1 ratio,
Externí odkaz:
https://doaj.org/article/a9366d642f7e4ad6972574b41e9b72ed
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Background: Pre-eclampsia is a serious consideration for women with type 1 diabetes mellitus (T1DM) planning pregnancy. Risk stratification strategies, such as biomarkers measured in the first trimester of pregnancy, could help identify high-risk wom
Externí odkaz:
https://doaj.org/article/7e6c53205a494ed4a60372727abf7019
Autor:
Michael Chhor, Hao Chen, Djurdja Jerotić, Milorad Tešić, Valentina N. Nikolić, Milan Pavlović, Rada M. Vučić, Benjamin Rayner, Chris J. Watson, Mark Ledwidge, Kenneth McDonald, Tracy Robson, Kristine C. McGrath, Lana McClements
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 395 (2023)
Heart failure (HF) is the leading cause of hospitalisations worldwide, with only 35% of patients surviving the first 5 years after diagnosis. The pathogenesis of HF with preserved ejection fraction (HFpEF) is still unclear, impeding the implementatio
Externí odkaz:
https://doaj.org/article/bbab7a93b95e4f2399fd6db0dc49f34a
Autor:
Chris J. Watson, Nadezhda Glezeva, Stephen Horgan, Joe Gallagher, Dermot Phelan, Ken McDonald, Michael Tolan, John Baugh, Patrick Collier, Mark Ledwidge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 11 (2020)
Background Atrial tissue fibrosis is linked to inflammatory cells, yet is incompletely understood. A growing body of literature associates peripheral blood levels of the antifibrotic hormone BNP (B‐type natriuretic peptide) with atrial fibrillation
Externí odkaz:
https://doaj.org/article/abe45682a2a0493b83700b6dbd04e9f2