Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Chris I Newbold"'
Autor:
Eerik Aunin, Ulrike Böhme, Theo Sanderson, Noah D Simons, Tony L Goldberg, Nelson Ting, Colin A Chapman, Chris I Newbold, Matthew Berriman, Adam J Reid
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008717 (2020)
Hepatocystis is a genus of single-celled parasites infecting, amongst other hosts, monkeys, bats and squirrels. Although thought to have descended from malaria parasites (Plasmodium spp.), Hepatocystis spp. are thought not to undergo replication in t
Externí odkaz:
https://doaj.org/article/2e2214cd623d46758992ca62517de627
Publikováno v:
eLife, Vol 2 (2013)
Antigenic variation in the human malaria parasite Plasmodium falciparum involves sequential and mutually exclusive expression of members of the var multi-gene family and appears to follow a non-random pattern. In this study, using a detailed in vitro
Externí odkaz:
https://doaj.org/article/7c2b82e1175e4c53a77963639a5d7d2a
Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.
Autor:
Mario Recker, Caroline O Buckee, Andrew Serazin, Sue Kyes, Robert Pinches, Zóe Christodoulou, Amy L Springer, Sunetra Gupta, Chris I Newbold
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001306 (2011)
Many pathogenic bacteria, fungi, and protozoa achieve chronic infection through an immune evasion strategy known as antigenic variation. In the human malaria parasite Plasmodium falciparum, this involves transcriptional switching among members of the
Externí odkaz:
https://doaj.org/article/69c4427ffae3482883a2ac9c357f4a22
Autor:
Peter C Bull, Matthew Berriman, Sue Kyes, Michael A Quail, Neil Hall, Moses M Kortok, Kevin Marsh, Chris I Newbold
Publikováno v:
PLoS Pathogens, Vol 1, Iss 3, p e26 (2005)
The variant surface antigens expressed on Plasmodium falciparum-infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var genes, about 60 of which are present within every par
Externí odkaz:
https://doaj.org/article/b3143e95dec0495e93e8ad94173cb676
Autor:
Mario Recker, Jennifer N. Musyoki, Jedidah Mwacharo, Adam J. Reid, Juliana Wambua, J J Valletta, Chris I. Newbold, Matthew Berriman, K Said, Edward Otieno, Kevin Marsh, Philip Bejon, Yaw Bediako, Jean Langhorne, Francis M. Ndungu, Addy Jwg., Joyce M. Ngoi
After decades of research, our understanding of when and why individuals infected with Plasmodium falciparum develop clinical malaria is still limited. Correlates of immune protection are often sought through prospective cohort studies, where measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c6c900b4bb0eaae90ec8b7c0cccfbd
Autor:
Adam J. Reid, Nelson Ting, Ulrike Böhme, Tony L. Goldberg, Noah D. Simons, Eerik Aunin, Theo Sanderson, Colin A. Chapman, Matthew Berriman, Chris I. Newbold
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 8, p e1008717 (2020)
PLoS Pathogens, Vol 16, Iss 8, p e1008717 (2020)
Hepatocystis is a genus of single-celled parasites infecting, amongst other hosts, monkeys, bats and squirrels. Although thought to have descended from malaria parasites (Plasmodium spp.), Hepatocystis spp. are thought not to undergo replication in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b83d55ca062adeb5b889cc37ee1e7a
http://europepmc.org/articles/PMC7425995
http://europepmc.org/articles/PMC7425995
Autor:
Chris I. Newbold, Dominic P. Kwiatkowski, Mandy Sanders, Samuel Assefa, Ulrike Böhme, Thomas D. Otto, Matthew Berriman
Publikováno v:
Wellcome Open Research
The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic. Here we have assembled nearly complete var gene repertoires from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe343809a9ebe5f4c1d7feec2589c65
http://europepmc.org/articles/PMC7001760
http://europepmc.org/articles/PMC7001760
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Here we describe the ways in which the sequence and annotation of the Plasmodium falciparum reference genome has changed since its publication in 2002. As the malaria species responsible for the most deaths worldwide, the richness of annotation and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::2ab6197b5414f966667e7febb2f5deb8
https://wellcomeopenresearch.org/articles/4-58/v2
https://wellcomeopenresearch.org/articles/4-58/v2
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Here we describe the ways in which the sequence and annotation of the Plasmodium falciparum reference genome has changed since its publication in 2002. As the malaria species responsible for the most deaths worldwide, the richness of annotation and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::e5e780ea76c87c54a253e160ba02e2f6
https://wellcomeopenresearch.org/articles/4-58/v1
https://wellcomeopenresearch.org/articles/4-58/v1
Autor:
Mandy Sanders, António M. Mendes, Cynthia K. Lee, Filipa Teixeira, Shahid M. Khan, Christian F. Ockenhouse, Thomas D. Otto, Carolina M. Andrade, Chris J. Janse, Chris I. Newbold, Nataniel Goncalves-Rosa, Dolores Bonaparte, Marta Machado, Isaie J. Reuling, João Sinfrónio, Yimin Wu, Miguel Prudêncio, Robert W. Sauerwein, Joana Pissarra, Matthew Berriman
Publikováno v:
npj Vaccines, 3
Npj Vaccines, 3
npj Vaccines, Vol 3, Iss 1, Pp 1-12 (2018)
npj Vaccines
Npj Vaccines, 3
npj Vaccines, Vol 3, Iss 1, Pp 1-12 (2018)
npj Vaccines
Whole-sporozoite vaccination/immunization induces high levels of protective immunity in both rodent models of malaria and in humans. Recently, we generated a transgenic line of the rodent malaria parasite P. berghei (Pb) that expresses the P. falcipa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc3bb970c0841d26bc55f6c8ce4bb76
https://hdl.handle.net/1887/86673
https://hdl.handle.net/1887/86673