Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Chris I, De Zeeuw"'
Autor:
Francesca Romana Fiocchi, Nikki E. S. van Dorp, Stephanie Dijkhuizen, Maurits van den Berg, Aaron Wong, Chris I. De Zeeuw, Henk-Jan Boele
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
The delicate balance between discrimination and generalization of responses is crucial for survival in our ever-changing environment. In particular, it is important to understand how stimulus discrimination affects the level of stimulus generalizatio
Externí odkaz:
https://doaj.org/article/ff8788c6d5464c248e575d0fe3a3dee1
Autor:
Elías Mateo Fernández Santoro, Arun Karim, Pascal Warnaar, Chris I. De Zeeuw, Aleksandra Badura, Mario Negrello
Publikováno v:
Frontiers in Computational Neuroscience, Vol 18 (2024)
The investigation of the dynamics of Purkinje cell (PC) activity is crucial to unravel the role of the cerebellum in motor control, learning and cognitive processes. Within the cerebellar cortex (CC), these neurons receive all the incoming sensory an
Externí odkaz:
https://doaj.org/article/8f7fe8bb6f69463fadd68be03c1f0d32
Autor:
Robin Broersen, Catarina Albergaria, Daniela Carulli, Megan R. Carey, Cathrin B. Canto, Chris I. De Zeeuw
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Associative learning during delay eyeblink conditioning (EBC) depends on an intact cerebellum. However, the relative contribution of changes in the cerebellar nuclei to learning remains a subject of ongoing debate. In particular, little is k
Externí odkaz:
https://doaj.org/article/be69cc697e52468aad862a371dd3a118
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Local feedforward and recurrent connectivity are rife in the frontal areas of the cerebral cortex, which gives rise to rich heterogeneous dynamics observed in such areas. Recently, similar local connectivity motifs have been discovered among
Externí odkaz:
https://doaj.org/article/e9b6d276bacb4bccb831eaa281f8103f
Autor:
Alice Geminiani, Claudia Casellato, Henk-Jan Boele, Alessandra Pedrocchi, Chris I De Zeeuw, Egidio D'Angelo
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1011277 (2024)
According to the motor learning theory by Albus and Ito, synaptic depression at the parallel fibre to Purkinje cells synapse (pf-PC) is the main substrate responsible for learning sensorimotor contingencies under climbing fibre control. However, rece
Externí odkaz:
https://doaj.org/article/4b567e9a741349cc97edf07de3261d4b
Autor:
Dick Jaarsma, Maria B. Birkisdóttir, Randy van Vossen, Demi W.G.D. Oomen, Oussama Akhiyat, Wilbert P. Vermeij, Sebastiaan K.E. Koekkoek, Chris I. De Zeeuw, Laurens W.J. Bosman
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106422- (2024)
Gait ataxia is one of the most common and impactful consequences of cerebellar dysfunction. Purkinje cells, the sole output neurons of the cerebellar cortex, are often involved in the underlying pathology, but their specific functions during locomoto
Externí odkaz:
https://doaj.org/article/30bb20c78e0f424eb5b4ce3fec82472a
Autor:
François G. C. Blot, Joshua J. White, Amy van Hattem, Licia Scotti, Vaishnavi Balaji, Youri Adolfs, R. Jeroen Pasterkamp, Chris I. De Zeeuw, Martijn Schonewille
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The classification of neuronal subpopulations has significantly advanced, yet its relevance for behavior remains unclear. The highly organized flocculus of the cerebellum, known to fine-tune multi-axial eye movements, is an ideal substrate f
Externí odkaz:
https://doaj.org/article/82fd7fa96c6f48598a238a279fec019b
Autor:
Sebastián Loyola, Tycho M Hoogland, Hugo Hoedemaker, Vincenzo Romano, Mario Negrello, Chris I De Zeeuw
Publikováno v:
eLife, Vol 12 (2023)
The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of plasticity. Given their important role in both short-term and long-term coordination o
Externí odkaz:
https://doaj.org/article/fe408a7b3a35414d8395bc5dbc4167b9
Autor:
Stijn Voerman, Bastiaan H. A. Urbanus, Martijn Schonewille, Joshua J. White, Chris I. De Zeeuw
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-7 (2022)
Electrophysiological recordings from Purkinje cells in mice show that the potential for induction of long-term depression may vary with molecular identity
Externí odkaz:
https://doaj.org/article/c0ec630b4ec84d1eb41d28615d3d4808
Autor:
Sadaf Soloukey, Luuk Verhoef, Bastian S. Generowicz, Chris I. De Zeeuw, Sebastiaan K. E. Koekkoek, Arnaud J. P. E. Vincent, Clemens M. F. Dirven, Biswadjiet S. Harhangi, Pieter Kruizinga
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
Surgical resection of spinal cord hemangioblastomas remains a challenging endeavor: the neurosurgeon’s aim to reach total tumor resections directly endangers their aim to minimize post-operative neurological deficits. The currently available tools
Externí odkaz:
https://doaj.org/article/58b08e5293f545b0be0cd390a125addf