Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Chris H, Takimoto"'
Autor:
Mark P. Chao, Chris H. Takimoto, Dong Dong Feng, Kelly McKenna, Phung Gip, Jie Liu, Jens-Peter Volkmer, Irving L. Weissman, Ravindra Majeti
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
In recent years, immunotherapies have been clinically investigated in AML and other myeloid malignancies. While most of these are focused on stimulating the adaptive immune system (including T cell checkpoint inhibitors), several key approaches targe
Externí odkaz:
https://doaj.org/article/8638e8ad243d4633b048ad522ad22867
Autor:
Genevive H. Hernandez, John So, Kathryn A. Logronio, Maya F. Kotturi, Won Seog Kim, Philippe Armand, Chan Y. Cheah, Ajay K. Gopal, Ian W. Flinn, Gareth P. Gregory, Matthew J. Matasar, Loretta J. Nastoupil, Catherine S. Diefenbach, Sung-Soo Yoon, Matthew Ku, Ibrahim Qazi, Maya K. Leabman, Iris Sison, Bruce A. Keyt, Chris H. Takimoto, Thomas J. Manley, Elizabeth L. Budde
Publikováno v:
Blood. 140:6436-6438
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c364a4faace6cccfd490fae66a692a
https://doi.org/10.1182/blood-2022-163235
https://doi.org/10.1182/blood-2022-163235
Autor:
Chris H. Takimoto, Erika Martinelli, Allan van Oosterom, Eric Walk, Kathryn Parker, Margaret Dugan, Jerry Huang, Christie Low, William Mietlowski, Clifford DiLea, Josep Tabernero, Frederico Rojo, Herlinde Dumez, Patrick Schöffski, Alain C. Mita, José Baselga
PDF file - 59K, Pharmacodynamic Parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e14cb944d79c031c6011a979c8d4e6
https://doi.org/10.1158/1078-0432.22447530.v1
https://doi.org/10.1158/1078-0432.22447530.v1
Autor:
Chris H. Takimoto, Sridhar Mani, Dale E. Shuster, Mendel Jansen, Fang Fang, Christopher Desjardins, Nancy Wong, Quincy S. Chu, Eric K. Rowinsky, Monica Mita, Alain C. Mita, Sanjay Goel
Editorial on this Article from A Phase I Study of Eribulin Mesylate (E7389), a Mechanistically Novel Inhibitor of Microtubule Dynamics, in Patients with Advanced Solid Malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a351f344895b818e22174cb35314bb7
https://doi.org/10.1158/1078-0432.22440229.v1
https://doi.org/10.1158/1078-0432.22440229.v1
Autor:
Chris H. Takimoto, Erika Martinelli, Allan van Oosterom, Eric Walk, Kathryn Parker, Margaret Dugan, Jerry Huang, Christie Low, William Mietlowski, Clifford DiLea, Josep Tabernero, Frederico Rojo, Herlinde Dumez, Patrick Schöffski, Alain C. Mita, José Baselga
PDF file - 56K, Mean Pharmacokinetic Parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727c4c0ce9450476bd0f0d51cbaf033a
https://doi.org/10.1158/1078-0432.22447533
https://doi.org/10.1158/1078-0432.22447533
Autor:
Chris H. Takimoto, Erika Martinelli, Allan van Oosterom, Eric Walk, Kathryn Parker, Margaret Dugan, Jerry Huang, Christie Low, William Mietlowski, Clifford DiLea, Josep Tabernero, Frederico Rojo, Herlinde Dumez, Patrick Schöffski, Alain C. Mita, José Baselga
PDF file - 72K, Most Frequent Adverse Events (≥ 15%, any dose group) by Initial Dose Group (Safety Population)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372cae8dbd0011744274748a2a24fcfc
https://doi.org/10.1158/1078-0432.22447536
https://doi.org/10.1158/1078-0432.22447536
Autor:
Chris H. Takimoto, Erika Martinelli, Allan van Oosterom, Eric Walk, Kathryn Parker, Margaret Dugan, Jerry Huang, Christie Low, William Mietlowski, Clifford DiLea, Josep Tabernero, Frederico Rojo, Herlinde Dumez, Patrick Schöffski, Alain C. Mita, José Baselga
PDF file - 50K, Primary Antibodies Used for Immunohistochemical Staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538b3b600179b1b5c819848bcd8092b1
https://doi.org/10.1158/1078-0432.22447539
https://doi.org/10.1158/1078-0432.22447539
Autor:
Chris H. Takimoto, Erika Martinelli, Allan van Oosterom, Eric Walk, Kathryn Parker, Margaret Dugan, Jerry Huang, Christie Low, William Mietlowski, Clifford DiLea, Josep Tabernero, Frederico Rojo, Herlinde Dumez, Patrick Schöffski, Alain C. Mita, José Baselga
Purpose: In this first-in-human study of AEE788, a tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR), HER-2, and VEGFR-2, a comprehensive pharmacodynamic program was implemented in addition to the evaluation of safety, pharmacokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fac8cfffc49db97f13c3f603843603
https://doi.org/10.1158/1078-0432.c.6521103
https://doi.org/10.1158/1078-0432.c.6521103
Autor:
Chris H. Takimoto, Sridhar Mani, Dale E. Shuster, Mendel Jansen, Fang Fang, Christopher Desjardins, Nancy Wong, Quincy S. Chu, Eric K. Rowinsky, Monica Mita, Alain C. Mita, Sanjay Goel
Purpose: Eribulin mesylate (E7389), a non-taxane microtubule dynamics inhibitor, is a structurally simplified, synthetic analogue of halichondrin B that acts via a mechanism distinct from conventional tubulin-targeted agents. This phase I study deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a73b8975cba01930f10a01137a7d5fa
https://doi.org/10.1158/1078-0432.c.6517579.v1
https://doi.org/10.1158/1078-0432.c.6517579.v1
Autor:
Raymond C. Bergan, Jill C. Pelling, Irene Helenowski, Chris H. Takimoto, Joshua Cooper, Vijayalakshmi Ananthanarayanan, Li Xu, Minalini Lakshman
Dietary genistein has been linked to lower prostate cancer (PCa) mortality. Metastasis is the ultimate cause of death from PCa. Cell detachment and invasion represent early steps in the metastatic cascade. We had shown that genistein inhibits PCa cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::817cdd5c4f50966456f8c0f62ddb3e5d
https://doi.org/10.1158/0008-5472.c.6497531
https://doi.org/10.1158/0008-5472.c.6497531