Zobrazeno 1 - 10
of 513
pro vyhledávání: '"Chris H, Polman"'
Autor:
Allen C. Bowling, MD, PhD, Dr. T. Jock Murray, MS, John H. Noseworthy, MD, Chris H. Polman, MD, PhD, Alan J. Thompson, MD, FRCP, FRCPI
The huge expansion of information available about MS, especially through the Internet, has put the individual with MS in a position to take increasing responsibility for her or his own care. There is thus a need for a comprehensive, readily accessibl
Autor:
Prejaas Tewarie, Menno M Schoonheim, Cornelis J Stam, Marieke L van der Meer, Bob W van Dijk, Frederik Barkhof, Chris H Polman, Arjan Hillebrand
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69318 (2013)
The relation between pathological findings and clinical and cognitive decline in Multiple Sclerosis remains unclear. Here, we tested the hypothesis that altered functional connectivity could provide a missing link between structural findings, such as
Externí odkaz:
https://doaj.org/article/8b4898cbdb5245ef8c2ee1037be4829d
Autor:
Martin Hardmeier, Menno M Schoonheim, Jeroen J G Geurts, Arjan Hillebrand, Chris H Polman, Frederik Barkhof, Cornelis J Stam
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42087 (2012)
BackgroundCognitive dysfunction in multiple sclerosis (MS) is frequent. Insight into underlying mechanisms would help to develop therapeutic strategies.ObjectiveTo explore the relationship of cognitive performance to patterns of nodal centrality deri
Externí odkaz:
https://doaj.org/article/999789c63f1e4013a8494d2a00e02e09
Autor:
Lisa G M van Baarsen, Saskia Vosslamber, Marianne Tijssen, Josefien M C Baggen, Laura F van der Voort, Joep Killestein, Tineke C T M van der Pouw Kraan, Chris H Polman, Cornelis L Verweij
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1927 (2008)
BackgroundMultiple sclerosis (MS) is a heterogeneous disease. In order to understand the partial responsiveness to IFNbeta in Relapsing Remitting MS (RRMS) we studied the pharmacological effects of IFNbeta therapy.MethodologyLarge scale gene expressi
Externí odkaz:
https://doaj.org/article/540228089a5342948db5eca8f6d61378
Autor:
Antonios Bayas, Kp Wandinger, Sten Fredrikson, Cyrille B. Confavreux, B. C. Kieseier, Ludwig Kappos, Mathias Buttmann, Jordi Río, J. De Keyser, David Brassat, Jens Kuhle, Giulio Disanto, Chris H. Polman, M Ecsedi, M. Frontoni, M Hardmeier, Michael Hutchinson, Markus Färkkilä, M. P. Amato, K Baum, T. Kümpfel, Claude Stolz, K Gugleta, M D’hooghe, E Roullet, Bruno Brochet, Karl Vass, Carmen Lienert, Gilles Edan
Publikováno v:
Kuhle, J, Hardmeier, M, Disanto, G, Gugleta, K, Ecsedi, M, Lienert, C, Amato, M P, Baum, K, Buttmann, M, Bayas, A, Brassat, D, Brochet, B, Confavreux, C, Edan, G, Färkkilä, M, Fredrikson, S, Frontoni, M, D'Hooghe, M, Hutchinson, M, De Keyser, J, Kieseier, B C, Kümpfel, T, Rio, J, Polman, C, Roullet, E, Stolz, C, Vass, K, Wandinger, K P & Kappos, L 2016, ' A 10-year follow-up of the European multicenter trial of interferon β-1b in secondary-progressive multiple sclerosis ', Multiple Sclerosis, vol. 22, no. 4, pp. 533-543 . https://doi.org/10.1177/1352458515594440
Multiple Sclerosis Journal
Multiple Sclerosis Journal, 2015, 22 (4), pp.533-43. ⟨10.1177/1352458515594440⟩
Multiple sclerosis (Houndmills Basingstoke England)
Multiple sclerosis journal, 22(4), 533-543. SAGE Publications Inc.
Multiple Sclerosis Journal, SAGE Publications, 2015, 22 (4), pp.533-43. ⟨10.1177/1352458515594440⟩
Multiple Sclerosis, 22(4), 533-543. SAGE Publications Ltd
Multiple Sclerosis Journal
Multiple Sclerosis Journal, 2015, 22 (4), pp.533-43. ⟨10.1177/1352458515594440⟩
Multiple sclerosis (Houndmills Basingstoke England)
Multiple sclerosis journal, 22(4), 533-543. SAGE Publications Inc.
Multiple Sclerosis Journal, SAGE Publications, 2015, 22 (4), pp.533-43. ⟨10.1177/1352458515594440⟩
Multiple Sclerosis, 22(4), 533-543. SAGE Publications Ltd
Objectives: To explore long-term effects of treatment and prognostic relevance of variables assessed at baseline and during the European secondary progressive multiple sclerosis (SPMS) trial of interferon beta 1b (IFNB-1b). Methods: We assessed 362 p
Autor:
Petra J. W. Pouwels, J. J. G. Geurts, Martijn D. Steenwijk, Chris H. Polman, E. M. M. Strijbis, G. J. A. Nagtegaal, Frederik Barkhof, O. T. Wiebenga, Hanneke E. Hulst, Menno M. Schoonheim
Publikováno v:
Wiebenga, O T, Schoonheim, M M, Hulst, H E, Nagtegaal, G J A, Strijbis, E M M, Steenwijk, M D, Polman, C H, Pouwels, P J W, Barkhof, F & Geurts, J J G 2016, ' White Matter Diffusion Changes during the First Year of Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis ', American Journal of Neuroradiology, vol. 37, no. 6, pp. 1030-1037 . https://doi.org/10.3174/ajnr.A4690
American Journal of Neuroradiology, 37(6), 1030-1037. American Society of Neuroradiology
AJNR Am J Neuroradiol
American Journal of Neuroradiology, 37(6), 1030-1037. American Society of Neuroradiology
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: Natalizumab treatment strongly affects relapsing-remitting multiple sclerosis, possibly by restraining white matter damage. This study investigated changes in white matter diffusivity in patients with relapsing-remitting multi
Autor:
Ludwig Kappos, Maria Pia Sormani, Maria A. Rocca, Mike P. Wattjes, Chris H. Polman, Frederik Barkhof, Nicola De Stefano, Franz Fazekas, David Miller, Cristina Auger, Alex Rovira, Mar Tintoré, Tarek A. Yousry, Carmen Tur, Massimo Filippi, Xavier Montalban
Publikováno v:
Nature Reviews Neurology. 11:597-606
The role of MRI in the assessment of multiple sclerosis (MS) goes far beyond the diagnostic process. MRI techniques can be used as regular monitoring to help stage patients with MS and measure disease progression. MRI can also be used to measure lesi
Autor:
Menno M. Schoonheim, Martijn D. Steenwijk, O. T. Wiebenga, Antoine Klauser, J. J. G. Geurts, Petra J. W. Pouwels, Frederik Barkhof, J.A. van Rossum, Chris H. Polman, G. J. A. Nagtegaal
Publikováno v:
American Journal of Neuroradiology, 36(6), 1116-1123. American Society of Neuroradiology
AJNR Am J Neuroradiol
Wiebenga, O T, Klauser, A M, Schoonheim, M M, Nagtegaal, G J A, Steenwijk, M D, van Rossum, J A, Polman, C H, Barkhof, F, Pouwels, P J W & Geurts, J J G 2015, ' Enhanced Axonal Metabolism during Early Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis ', American Journal of Neuroradiology, vol. 36, no. 6, pp. 1116-1123 . https://doi.org/10.3174/ajnr.A4252
AJNR Am J Neuroradiol
Wiebenga, O T, Klauser, A M, Schoonheim, M M, Nagtegaal, G J A, Steenwijk, M D, van Rossum, J A, Polman, C H, Barkhof, F, Pouwels, P J W & Geurts, J J G 2015, ' Enhanced Axonal Metabolism during Early Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis ', American Journal of Neuroradiology, vol. 36, no. 6, pp. 1116-1123 . https://doi.org/10.3174/ajnr.A4252
BACKGROUND AND PURPOSE: The considerable clinical effect of natalizumab in patients with relapsing-remitting multiple sclerosis might be explained by its possible beneficial effect on axonal functioning. In this longitudinal study, the effect of nata
Autor:
Marita Daams, Frederik Barkhof, Mike P. Wattjes, B.M.J. Uitdehaag, Prejaas Tewarie, Hugo Vrenken, Chris H. Polman, Joep Killestein, Lisanne J. Balk, Martijn D. Steenwijk, Axel Petzold
Publikováno v:
Balk, L J, Steenwijk, M D, Tewarie, P, Daams, M, Killestein, J, Wattjes, M P, Vrenken, H, Barkhof, F, Polman, C H, Uitdehaag, B M J & Petzold, A F S 2015, ' Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis ', Journal of Neurology, Neurosurgery and Psychiatry, vol. 86, no. 4, pp. 419-424 . https://doi.org/10.1136/jnnp-2014-308189
Journal of Neurology, Neurosurgery and Psychiatry, 86(4), 419-424. BMJ Publishing Group
Journal of Neurology, Neurosurgery and Psychiatry, 86(4), 419-424. BMJ Publishing Group
Objective To investigate the coexistence of anterograde and retrograde trans-synaptic axonal degeneration, and to explore the relationship between selective visual pathway damage and global brain involvement in longstanding multiple sclerosis (MS). M
Autor:
Femke A.H. van der Linden, Chris H. Polman, Bernard M. J. Uitdehaag, Lisanne J. Balk, L.V.A.E. Bosma, Judith M Sonder
Publikováno v:
Sonder, J M, Balk, L J, van der Linden, F A H, Bosma, L V A E, Polman, C H & Uitdehaag, B M J 2015, ' Toward the use of proxy reports for estimating long-term patient-reported outcomes in multiple sclerosis ', Multiple Sclerosis, vol. 21, no. 14, pp. 1865-1871 . https://doi.org/10.1177/1352458514544078
Multiple Sclerosis, 21(14), 1865-1871. SAGE Publications Ltd
Multiple Sclerosis, 21(14), 1865-1871. SAGE Publications Ltd
Background: Assessment of disease impact in multiple sclerosis (MS) is usually driven by information obtained directly from patients using patient-reported outcomes. However, when patients’ response in longitudinal studies is less reliable or missi