Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chris Gates"'
Autor:
Charles A. Whittaker, Alper Kucukural, Chris Gates, Owen Michael Wilkins, George W. Bell, John N. Hutchinson, Shawn W. Polson, Julie Dragon
Publikováno v:
J Biomol Tech
The functional annotation of gene lists is a common analysis routine required for most genomics experiments, and bioinformatics core facilities must support these analyses. In contrast to methods such as the quantitation of RNA-Seq reads or different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744f7b3205a60ad9a1a28eda79fefa3a
https://europepmc.org/articles/PMC10121236/
https://europepmc.org/articles/PMC10121236/
Autor:
Meifang Yu, Jason B. Fleming, Rena Levin-Klein, Steven Gallinger, Susan R. Ross, Cullen M. Taniguchi, Chris Gates, Dhwani N. Rupani, Sara L. Manning, Runsheng Wang, Michael P. Kim, Kimal I. Rajapakshe, Fredrik I. Thege, Reuben S. Harris, Weisheng Wu, S Wörmann, Matthew H G Katz, Faiyaz Notta, Asha S. Multani, Amy Zhang, Ya’an Kang, Anirban Maitra, Andrew D. Rhim, Ravikanth Maddipati, Melena D. Bellin, Robert W. Cowan, Katharina Schlacher
Publikováno v:
Nature Cancer. 2:1338-1356
Despite efforts in understanding its underlying mechanisms, the etiology of chromosomal instability (CIN) remains unclear for many tumor types. Here, we identify CIN initiation as a previously undescribed function for APOBEC3A (A3A), a cytidine deami
Autor:
Sonja Maria Woermann, Amy Zhang, Fredrik I. Thege, Chris Gates, Reuben S. Harris, Susan R. Ross, Faiyaz Notta, Anirban Maitra, Andrew D. Rhim
Publikováno v:
Cancer Research. 82:1506-1506
Chromosomal instability (CIN), a hallmark of cancer, has been associated with a highly metastatic phenotype in numerous cancers. Mechanisms by which these genomic events occur during the lifespan of a neoplasm have yet to be fully delineated. In our
Publikováno v:
Cancer Research. 82:1332-1332
Adenosine-to-Inosine (A-to-I) RNA editing is mediated by Adenosine deaminase acting on RNA (Adar) enzymes. The resulting A-to-I edit in RNA alters its post-transcriptional processing making Adar1 a critical regulator of gene expression. In line with
Autor:
Sonja M, Wörmann, Amy, Zhang, Fredrik I, Thege, Robert W, Cowan, Dhwani N, Rupani, Runsheng, Wang, Sara L, Manning, Chris, Gates, Weisheng, Wu, Rena, Levin-Klein, Kimal I, Rajapakshe, Meifang, Yu, Asha S, Multani, Ya'an, Kang, Cullen M, Taniguchi, Katharina, Schlacher, Melena D, Bellin, Matthew H G, Katz, Michael P, Kim, Jason B, Fleming, Steven, Gallinger, Ravikanth, Maddipati, Reuben S, Harris, Faiyaz, Notta, Susan R, Ross, Anirban, Maitra, Andrew D, Rhim
Publikováno v:
Nature cancer. 2(12)
Despite efforts in understanding its underlying mechanisms, the etiology of chromosomal instability (CIN) remains unclear for many tumor types. Here, we identify CIN initiation as a previously undescribed function for APOBEC3A (A3A), a cytidine deami
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988754
This chapter contains a step-by-step protocol for identifying somatic SNPs and small Indels from next-generation sequencing data of tumor samples and matching normal samples. The workflow presented here is largely based on the Broad Institute's "Best
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5403afa3bfaaf31f036ac0bb0ad98a1f
https://doi.org/10.1007/978-1-4939-8876-1_21
https://doi.org/10.1007/978-1-4939-8876-1_21
Autor:
Chris Gates, Andi K. Cani, Joel K. Greenson, Rork Kuick, Ana R. Grant, Jianhua Liu, Scott A. Tomlins, Karin M. Hardiman, Daniel H. Hovelson, Peter J. Ulintz, Ashwini Bhasi, Eric R. Fearon
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Colorectal cancer arises in part from the cumulative effects of multiple gene lesions. Recent studies in selected cancer types have revealed significant intra-tumor genetic heterogeneity and highlighted its potential role in disease progression and r
Autor:
John N. Hutchinson, Jyothi Thimmapuram, Shannan J. Ho Sui, Chris Gates, R Krishna Murthy Karuturi, Alberto Riva, Alper Kucukural, Julie A. Dragon, Shawn W. Polson, Stuart S. Levine, Matthew L. Settles
Publikováno v:
J Biomol Tech
Over the last decade, the cost of -omics data creation has decreased 10-fold, whereas the need for analytical support for those data has increased exponentially. Consequently, bioinformaticians face a second wave of challenges: novel applications of
Autor:
Alexandra Calinescu, Chris Gates, Zain Sultan, Sabrina Rocco, Gregory A. Clines, Nicholas J. Szerlip
Publikováno v:
Neuro Oncol
The spine is a common site of metastatic spread of many cancers, causing debilitating pain and suffering. Treatment of spinal metastases is limited by resistance to radiation, chemotherapy, and proximity to the spinal cord. It is currently not known
Autor:
Robert M. Panas, Glenn Larkin, Paul H. Pax, Lisa Poyneer, Jay W. Dawson, S. Mark Ammons, David Palmer, Chris Gates, D. Homoelle, Brian Hackel, Michael Kim, Brian J. Bauman, Greg Burton
Publikováno v:
Adaptive Optics Systems VI.
The performance of high-contrast AO instruments (GPI, SPHERE, ScEXAO, MagAO) and other systems that operate at visible wavelengths can be severely hampered by control system latencies and temporal wavefront errors. In high-contrast systems, temporal