Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Chris Galanos"'
Autor:
Sandrine Tchaptchet, Marina Gumenscheimer, Christoph Kalis, Nikolaus Freudenberg, Christoph Hölscher, Carsten J Kirschning, Marinus Lamers, Chris Galanos, Marina A Freudenberg
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39155 (2012)
Propionibacterium acnes is usually a relatively harmless commensal. However, under certain, poorly understood conditions it is implicated in the etiology of specific inflammatory diseases. In mice, P. acnes exhibits strong immunomodulatory activity l
Externí odkaz:
https://doaj.org/article/fd2a8b577e9444a89e210b1f6807adc9
Autor:
Ines Müller, György Fejer, Michael Huber, Peter J. Nielsen, Simone Keck, Chris Galanos, Sandrine Tchaptchet, Iva Savic, Marina A. Freudenberg
Publikováno v:
The Journal of Immunology. 186:5478-5488
In macrophages, two signaling pathways, dependent on MyD88 or TIR domain-containing adaptor-inducing IFN-β (TRIF) signaling, emanate from the LPS receptor TLR4/MD-2. In this study, we show that in murine bone marrow-derived mast cells (BMMCs), only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3a16558e496a9f895d6964d36b6032
https://doi.org/10.4049/jimmunol.1000458
https://doi.org/10.4049/jimmunol.1000458
Autor:
Thomas Vogl, Verena Müller, Marc Schmidt, Sandrine Tchaptchet, Matthias Goebeler, Johannes Roth, Arne Skerra, Stefan F. Martin, Peter J. Nielsen, Marina A. Freudenberg, Chris Galanos, Simone Keck, Badrinarayanan Raghavan, György Fejer, Christoph Kalis
Publikováno v:
Nature Immunology. 11:814-819
Allergies to nickel (Ni(2+)) are the most frequent cause of contact hypersensitivity (CHS) in industrialized countries. The efficient development of CHS requires both a T lymphocyte-specific signal and a proinflammatory signal. Here we show that Ni(2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bfaddb40992b0fcdc93965db57b89f
https://doi.org/10.1038/ni.1919
https://doi.org/10.1038/ni.1919
Autor:
Stefanie Liller, Eva Bachtanian, Jan C. Dudda, Markus M. Heimesaat, Stefan Bereswill, Christoph Dürr, Christian C. Termeer, György Fejer, Nikolaus Freudenberg, Stefan F. Martin, Chris Galanos, Thilo Jakob, Caroline Johner, Annalisa Lembo, Marina A. Freudenberg, Ralitsa Vassileva
Publikováno v:
The Journal of Experimental Medicine
Allergic contact hypersensitivity (CHS) is a T cell-mediated inflammatory skin disease. Interleukin (IL)-12 is considered to be important in the generation of the allergen-specific T cell response. Loss of IL-12 function in IL-12Rbeta2-deficient mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fa5128e3b02051c31136051f6fbfa9
https://doi.org/10.1084/jem.20070509
https://doi.org/10.1084/jem.20070509
Autor:
Michael Huber, Chris Galanos, Gordon Grochowy, Wolfgang G. Bessler, Gerald Krystal, Fillip Port, Christoph Kalis, Marina A. Freudenberg, Kerstin Fehrenbach
Publikováno v:
Molecular Immunology. 44:2087-2094
Little is known about the interplay between pathophysiological processes of allergy and infection, particularly with respect to mast cell (MC)-mediated responses. The presence and recognition of pathogen-associated molecular patterns (PAMPs) might ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c00c1656cf674735c3312413f67e0f
https://doi.org/10.1016/j.molimm.2006.09.011
https://doi.org/10.1016/j.molimm.2006.09.011
Autor:
Sandra Balkow, Marina Gumenscheimer, Markus M. Simon, Marina A. Freudenberg, Chris Galanos, Emilio Jirillo
Publikováno v:
Medical Microbiology and Immunology. 196:79-88
We investigated the effect of a primary non-lethal infection with lymphocytic choriomeningitis virus (LCMV) on the course and outcome of a secondary infection with the Gram-negative Salmonella enterica serovar Typhimurium or the Gram-positive Listeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a637a3dc852b37bcd029ae23317baa84
https://doi.org/10.1007/s00430-006-0030-1
https://doi.org/10.1007/s00430-006-0030-1
Autor:
Pascale Kropf, N. Freudenberg, Marina A. Freudenberg, Manuel Modolell, Chris Galanos, Ines Müller, Shanti Herath, Christoph Kalis
Publikováno v:
Journal of Leukocyte Biology. 76:48-57
The innate immune system is essential for host defense; it senses the presence of potentially pathogenic-invading microorganisms, and the contribution of Toll-like receptors (TLRs) to this response is increasingly recognized. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2884f4d5fdbea29b1d05fa5c8dad425
https://doi.org/10.1189/jlb.1003484
https://doi.org/10.1189/jlb.1003484
Autor:
Emilio Jirillo, Vincenzo Mitolo, Annalisa Lembo, Hermann Wagner, Christoph Kalis, Marina A. Freudenberg, Chris Galanos, Carsten J. Kirschning
Publikováno v:
Infection and Immunity. 71:6058-6062
The contribution of murine Toll-like receptors 2 and 4 (TLR2 and -4, respectively) to cytokine induction by heat-killed bacteria was analyzed in vitro and in vivo. Gram-negative bacteria induced cytokines primarily via TLR4; the contribution of TLR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf355d08fe86cdbe74ff0cc052ab3ef
https://doi.org/10.1128/iai.71.10.6058-6062.2003
https://doi.org/10.1128/iai.71.10.6058-6062.2003
Autor:
Marina Gumenscheimer, Chris Galanos, Yolande Chvatchko, Marina A. Freudenberg, Christoph Kalis, Thomas Merlin
Publikováno v:
Journal of Endotoxin Research. 9:308-312
The innate immune response to Gram-negative bacteria depends mainly on the ability of the host to respond to the LPS component. Consequently, the state of LPS sensitivity at the time of infection and the numbers of invading bacteria (i.e. the amounts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb3c713d651e94cc831385e0c4157a1
https://doi.org/10.1177/09680519030090050601
https://doi.org/10.1177/09680519030090050601