Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chris Evelo"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Nanomaterials hold great promise for improving our society, and it is crucial to understand their effects on biological systems in order to enhance their properties and ensure their safety. However, the lack of consistency in experimental re
Externí odkaz:
https://doaj.org/article/3ec313abdc404f69827307843847de80
Autor:
Philippe Rocca-Serra, Wei Gu, Vassilios Ioannidis, Tooba Abbassi-Daloii, Salvador Capella-Gutierrez, Ishwar Chandramouliswaran, Andrea Splendiani, Tony Burdett, Robert T. Giessmann, David Henderson, Dominique Batista, Ibrahim Emam, Yojana Gadiya, Lucas Giovanni, Egon Willighagen, Chris Evelo, Alasdair J. G. Gray, Philip Gribbon, Nick Juty, Danielle Welter, Karsten Quast, Paul Peeters, Tom Plasterer, Colin Wood, Eelke van der Horst, Dorothy Reilly, Herman van Vlijmen, Serena Scollen, Allyson Lister, Milo Thurston, Ramon Granell, the FAIR Cookbook Contributors, Susanna-Assunta Sansone
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract The notion that data should be Findable, Accessible, Interoperable and Reusable, according to the FAIR Principles, has become a global norm for good data stewardship and a prerequisite for reproducibility. Nowadays, FAIR guides data policy a
Externí odkaz:
https://doaj.org/article/ee1aae4367004e42bfdd9ed8a262bd13
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Protein mutations, especially those which occur in the binding site, play an important role in inter-individual drug response and may alter binding affinity and thus impact the drug’s efficacy and side effects. Unfortunately, large-scale e
Externí odkaz:
https://doaj.org/article/0d68f218410c4d5b8444f0d9376717f4
Publikováno v:
Journal of Cheminformatics, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract A key concept in drug design is how natural variants, especially the ones occurring in the binding site of drug targets, affect the inter-individual drug response and efficacy by altering binding affinity. These effects have been studied on
Externí odkaz:
https://doaj.org/article/930c97fb54754568a14ebe7213f2914d
Autor:
Rebecca Wilson, Paul Burton, Innes Asher, Kim Carter, Adriana Castelli, David Cumin, Chris Evelo, Lesley Stewart, Kelvin Tsoi, Emma White
Publikováno v:
International Journal of Population Data Science, Vol 1, Iss 1 (2017)
ABSTRACT Objectives The effective exploitation of what are often called big data is increasingly important. They provide the evidence in evidence-based health care and underpin scientific progress in many domains including social/economic policy.
Externí odkaz:
https://doaj.org/article/d48ea9ecc1bc410b96547f20c888df13
Autor:
Lars Eijssen, Chris Evelo, Ruben Kok, Barend Mons, Rob Hooft, and the other founding members of DTL Data (see Acknowledgements)
Publikováno v:
F1000Research, Vol 4 (2016)
We describe the Data programme of the Dutch Techcentre for Life Sciences (DTL, www.dtls.nl). DTL is a new national organisation in scientific research that facilitates life scientists with technologies and technological expertise in an era where new
Externí odkaz:
https://doaj.org/article/28bcfc27cf914230b963addabfe14d4e
Autor:
Robert Caesar, Monia Manieri, Thomas Kelder, Mark Boekschoten, Chris Evelo, Michael Müller, Teake Kooistra, Saverio Cinti, Robert Kleemann, Christian A Drevon
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11525 (2010)
Depot-dependent differences in adipose tissue physiology may reflect specialized functions and local interactions between adipocytes and surrounding tissues. We combined time-resolved microarray analyses of mesenteric- (MWAT), subcutaneous- (SWAT) an
Externí odkaz:
https://doaj.org/article/c9236cd19ad548908342f0d6d43f87f4
Autor:
Robert Kleemann, Marjan van Erk, Lars Verschuren, Anita M van den Hoek, Maud Koek, Peter Y Wielinga, Annie Jie, Linette Pellis, Ivana Bobeldijk-Pastorova, Thomas Kelder, Karin Toet, Suzan Wopereis, Nicole Cnubben, Chris Evelo, Ben van Ommen, Teake Kooistra
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8817 (2010)
BACKGROUND: The sequence of events leading to the development of insulin resistance (IR) as well as the underlying pathophysiological mechanisms are incompletely understood. As reductionist approaches have been largely unsuccessful in providing an un
Externí odkaz:
https://doaj.org/article/d5cf0678a8b447d285ad1f1ddb222232
Autor:
Thomas Kelder, Alexander R Pico, Kristina Hanspers, Martijn P van Iersel, Chris Evelo, Bruce R Conklin
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6447 (2009)
WikiPathways is a platform for creating, updating, and sharing biological pathways [1]. Pathways can be edited and downloaded using the wiki-style website. Here we present a SOAP web service that provides programmatic access to WikiPathways that is c
Externí odkaz:
https://doaj.org/article/d26135ccf4444b89931d591aec6ac7a5
Autor:
Alexander R Pico, Thomas Kelder, Martijn P van Iersel, Kristina Hanspers, Bruce R Conklin, Chris Evelo
Publikováno v:
PLoS Biology, Vol 6, Iss 7, p e184 (2008)
Externí odkaz:
https://doaj.org/article/0ba026058d7244cf8b043eb3d0955f4c