Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Chris E. Adkins"'
Autor:
Afroz S. Mohammad, Chris E. Adkins, Neal Shah, Rawaa Aljammal, Jessica I. G. Griffith, Rachel M. Tallman, Katherine L. Jarrell, Paul R. Lockman
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Brain tumor vasculature can be significantly compromised and leakier than that of normal brain blood vessels. Little is known if there are vascular permeability alterations in the brain adjacent to tumor (BAT). Changes in BAT perm
Externí odkaz:
https://doaj.org/article/de416521042f42179c8a72744bd02d0a
Autor:
Paul R. Lockman, Quentin R. Smith, Patricia S. Steeg, Diane Palmieri, Werner J. Geldenhuys, Hussaini S. Qhattal, Tori B. Terrell, Kaci A. Bohn, Mohamed I. Nounou, Chris E. Adkins, Xinli Liu, Rajendar K. Mittapalli
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4348ef172d10dda0efed15afe750aad9
https://doi.org/10.1158/1535-7163.22498963.v1
https://doi.org/10.1158/1535-7163.22498963.v1
Autor:
Paul R. Lockman, Quentin R. Smith, Patricia S. Steeg, Diane Palmieri, Werner J. Geldenhuys, Hussaini S. Qhattal, Tori B. Terrell, Kaci A. Bohn, Mohamed I. Nounou, Chris E. Adkins, Xinli Liu, Rajendar K. Mittapalli
Supplementary Figure S1: NMR Spectra of HA-Paclitaxel. 1H-NMR spectrum of HA-paclitaxel. Specific groups of HA-paclitaxel are shown with arrows; Supplementary Figure S2: Representative bioluminescent images of animals 24 hrs after intracardiac inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d4c2967d321eaf76a741dc90a28d38
https://doi.org/10.1158/1535-7163.22498960
https://doi.org/10.1158/1535-7163.22498960
Autor:
Brunilde Gril, Patricia S. Steeg, Priscilla K. Brastianos, Naema Nayyar, Renata Duchnowska, Ewa Izycka-Swieszewska, Wojciech Kloc, Seth M. Steinberg, David J. Liewehr, Diane Palmieri, Emily Hua, Emily Sechrest, Afroz Shareef Mohammad, Chris E. Adkins, Paul R. Lockman, L. Tiffany Lyle
Purpose: The blood–brain barrier (BBB) is modified to a blood–tumor barrier (BTB) as a brain metastasis develops from breast or other cancers. We (i) quantified the permeability of experimental brain metastases, (ii) determined the composition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9f6a23dc74202c049512d6d2c895e8
https://doi.org/10.1158/1078-0432.c.6523620
https://doi.org/10.1158/1078-0432.c.6523620
Autor:
Paul R. Lockman, Julie A. Lockman, Afroz S. Mohammad, Kaci. A. Bohn, Chris E. Adkins, Rajendar K. Mittapalli
Tumors residing in the central nervous system (CNS) compromise the blood–brain barrier (BBB) via increased vascular permeability, with the magnitude of changes dependent on the tumor type and location. Current studies determine penetrability of a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48843e10cfb0973749a58566f74a046c
https://doi.org/10.1158/0008-5472.c.6509664.v1
https://doi.org/10.1158/0008-5472.c.6509664.v1
Autor:
Quentin R. Smith, Patricia S. Steeg, Diane Palmieri, Suyun Huang, Julie A. Gaasch, Helen R. Thorsheim, Amanda Roberts, Chris E. Adkins, Kaci A. Bohn, Brunilde Gril, Vinay Rudraraju, Kunal S. Taskar, Rajendar K. Mittapalli, Paul R. Lockman
Purpose: Brain metastases of breast cancer appear to be increasing in incidence, confer significant morbidity, and threaten to compromise gains made in systemic chemotherapy. The blood–tumor barrier (BTB) is compromised in many brain metastases; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a16907fc4bac304223f3b189fd15531
https://doi.org/10.1158/1078-0432.c.6519378
https://doi.org/10.1158/1078-0432.c.6519378
Autor:
Quentin R. Smith, Patricia S. Steeg, Diane Palmieri, Suyun Huang, Julie A. Gaasch, Helen R. Thorsheim, Amanda Roberts, Chris E. Adkins, Kaci A. Bohn, Brunilde Gril, Vinay Rudraraju, Kunal S. Taskar, Rajendar K. Mittapalli, Paul R. Lockman
CCR Translation for This Article from Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77995049de131a3c3603b42e8b64a019
https://doi.org/10.1158/1078-0432.22442712
https://doi.org/10.1158/1078-0432.22442712
Autor:
Brunilde Gril, Patricia S. Steeg, Priscilla K. Brastianos, Naema Nayyar, Renata Duchnowska, Ewa Izycka-Swieszewska, Wojciech Kloc, Seth M. Steinberg, David J. Liewehr, Diane Palmieri, Emily Hua, Emily Sechrest, Afroz Shareef Mohammad, Chris E. Adkins, Paul R. Lockman, L. Tiffany Lyle
Supplemental Tables. Supplemental Tables S1-6. Table S1. Antibodies used for quantification and concentrations. Table S2. Antibodies that could not be quantified in the model systems under fixation conditions used to identify Texas Red dextran permea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ae0f24212cd903564fb0a185ea74d0
https://doi.org/10.1158/1078-0432.22457559.v1
https://doi.org/10.1158/1078-0432.22457559.v1
Autor:
Quentin R. Smith, Patricia S. Steeg, Diane Palmieri, Suyun Huang, Julie A. Gaasch, Helen R. Thorsheim, Amanda Roberts, Chris E. Adkins, Kaci A. Bohn, Brunilde Gril, Vinay Rudraraju, Kunal S. Taskar, Rajendar K. Mittapalli, Paul R. Lockman
Supplementary Figures S1-S9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8677241e239abc2630c66fe7932869de
https://doi.org/10.1158/1078-0432.22442709
https://doi.org/10.1158/1078-0432.22442709
Autor:
Paul R. Lockman, Julie A. Lockman, Afroz S. Mohammad, Kaci. A. Bohn, Chris E. Adkins, Rajendar K. Mittapalli
Supplementary figures showing representative histology and tracer distribution in the brain tumor models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347291a064cedfffb9a1df14489493f9
https://doi.org/10.1158/0008-5472.22416849
https://doi.org/10.1158/0008-5472.22416849