Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chris Doumen"'
Autor:
Chris Doumen
Publikováno v:
Gene. 505:276-282
Lombricine kinase is an annelid enzyme that belongs to the phosphagen kinase family of which creatine kinase and arginine kinase are the typical representatives. The enzymes play important roles in the cellular energy metabolism of animals. Biochemic
Autor:
Chris Doumen
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 156:137-143
Creatine kinase and arginine kinase are the typical representatives of an eight-member phosphagen kinase family, which play important roles in the cellular energy metabolism of animals. The phylum Annelida underwent a series of evolutionary processes
Autor:
Helen Zhu, Chris Doumen
Publikováno v:
Zoological Science. 26:284-288
A cytoplasmic manganese superoxide dismutase (cMnSOD) cDNA was cloned from the hepatopancreas of the red swamp crawfish, Procambarus clarkii. An initial cDNA fragment was identified by using degenerate primers, and the complete sequence was obtained
Autor:
Kathryn F. LaNoue, Chris Doumen, J. Michael O'Donnell, Xin Yu, Lawrence T. White, E. Douglas Lewandowski
Publikováno v:
Circulation Research. 81:165-175
Abstract To examine metabolic regulation in postischemic hearts, we examined oxidative recycling of 13 C within the glutamate pool (GLU) of intact rabbit hearts. Isolated hearts oxidized 2.5 mmol/L [2- 13 C]acetate during normal conditions (n=6) or d
Autor:
Chris Doumen, Kathryn F. LaNoue, Lawrence T. White, Xin Yu, Lisa A. Damico, E. Douglas Lewandowski
Publikováno v:
Magnetic Resonance in Medicine. 35:149-154
For the first time, 13C NMR signals are shown from 13C-enriched, low-level tricarboxylic acid (TCA) cycle intermediates from extracts of normal cardiac tissue. As the low tissue content of the key intermediates alpha-ketoglutarate (alpha-KG) and succ
Autor:
Lisa A. Damico, Kathryn F. LaNoue, Nathaniel M. Alpert, E. D. Lewandowski, Xin Yu, Lawrence T. White, Chris Doumen
Publikováno v:
Biophysical Journal. 69(5):2090-2102
Control of oxidative metabolism was studied using 13C NMR spectroscopy to detect rate-limiting steps in 13C labeling of glutamate. 13C NMR spectra were acquired every 1 or 2 min from isolated rabbit hearts perfused with either 2.5 mM [2-13C]acetate o
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 269:H515-H523
The biochemical link providing effective coordination between the mitochondrial ATP synthetic machinery and the contractile apparatus following transitions in cardiac work remains enigmatic. Studies were designed to determine whether activation of th
Publikováno v:
Scopus-Elsevier
The myocardium responds to alterations in cardiac work by changing its rate of O2 consumption. This reflects an increase in the oxidative synthesis of ATP to meet the contractile demand for ATP. However, the biochemical mechanisms responsible for inc
Publikováno v:
Cardiovascular toxicology. 10(4)
HIV-1 infection has been associated with cardiomyopathy in a subset of patients. In order to determine whether HIV-1 alters myocardial function or the myocardial response to stress, transgenic mice that express the HIV-1 protein Tat were used. Heart
Autor:
Chris Doumen, W. R. Ellington
Publikováno v:
Journal of Experimental Zoology. 261:394-405
Dissociation constants for MgATP [Kd(MgATP)] were measured with the combined techniques of spectrophotometry using the metallochromic dye, Antipyrylazo III, and phosphorus nuclear magnetic resonance (31P-NMR) spectroscopy. Values of the Kd(MgATP) wer