Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Chris D. Vulpe"'
Autor:
Marco Grodzki, Andrew P. Bluhm, Moritz Schaefer, Abderrahmane Tagmount, Max Russo, Amin Sobh, Roya Rafiee, Chris D. Vulpe, Stephanie M. Karst, Michael H. Norris
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background The COVID-19 pandemic has resulted in 275 million infections and 5.4 million deaths as of December 2021. While effective vaccines are being administered globally, there is still a great need for antiviral therapies as antigenicall
Externí odkaz:
https://doaj.org/article/0389603ba2a943b3a03f0bb2d378231d
Autor:
Feiyang Ma, Brie K. Fuqua, Yehudit Hasin, Clara Yukhtman, Chris D. Vulpe, Aldons J. Lusis, Matteo Pellegrini
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background 3’ RNA sequencing provides an alternative to whole transcript analysis. However, we do not know a priori the relative advantage of each method. Thus, a comprehensive comparison between the whole transcript and the 3′ method is
Externí odkaz:
https://doaj.org/article/924e10afdad745dcb048f52b08f74371
Autor:
Min Chen, Jiashuo Zheng, Guohao Liu, En Xu, Junzhuo Wang, Brie K. Fuqua, Chris D. Vulpe, Gregory J. Anderson, Huijun Chen
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 432-439 (2018)
Little is known about the iron efflux from the pancreas, but it is likely that multicopper ferroxidases (MCFs) are involved in this process. We thus used hephaestin (Heph) and ceruloplasmin (Cp) single-knockout mice and Heph/Cp double-knockout mice t
Externí odkaz:
https://doaj.org/article/34a476480a7849a7adb7826b8c552dd7
Autor:
Brie K. Fuqua, Yan Lu, David M. Frazer, Deepak Darshan, Sarah J. Wilkins, Linda Dunn, Alex V. Loguinov, Scott C. Kogan, Pavle Matak, Huijun Chen, Joshua L. Dunaief, Chris D. Vulpe, Gregory J. Anderson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 405-427 (2018)
Background & Aims: Multicopper ferroxidases (MCFs) facilitate intestinal iron absorption and systemic iron recycling, likely by a mechanism involving the oxidization of Fe2+ from the iron exporter ferroportin 1 for delivery to the circulating Fe3+ ca
Externí odkaz:
https://doaj.org/article/9a243689ff084d4d862aa74169ab9bf1
Autor:
Caglar Doguer, Jung-Heun Ha, Sukru Gulec, Chris D. Vulpe, Gregory J. Anderson, James F. Collins
Publikováno v:
Blood Advances, Vol 1, Iss 17, Pp 1335-1346 (2017)
Abstract: Regulation of intestinal iron absorption is crucial to maintain body iron levels because humans have no regulated iron-excretory system. Elucidating molecular events that mediate intestinal iron transport is thus important for the developme
Externí odkaz:
https://doaj.org/article/e6cb35695064469ca33d94537fde9c1c
Functional toxicogenomic profiling expands insight into modulators of formaldehyde toxicity in yeast
Autor:
Matthew North, Brandon David Gaytán, Carlos Romero, Vanessa Y. De La Rosa, Alex Loguinov, Martyn Smith, Luoping Zhang, Chris D. Vulpe
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
Formaldehyde (FA) is a commercially important chemical with numerous and diverse uses. Accordingly, occupational and environmental exposure to FA is prevalent worldwide. Various adverse effects, including nasopharyngeal, sinonasal, and lymphohematopo
Externí odkaz:
https://doaj.org/article/3aa4378cb0c54addb17fb08786ea4287
Autor:
Sajid Khan, Abderrahmane Tagmount, Elizabeth A. Williamson, Xuan Zhang, Dinesh Thummuri, Vivekananda Budamagunta, Ashwin Akki, Jose G. Trevino, Janet S. Wiegand, Daohong Zhou, Amin Sobh, Peiyi Zheng, Guangrong Zheng, Alex Loguinov, Chris D. Vulpe, Andrea N. Riner, Patrick W. Underwood, Robert Hromas
Publikováno v:
Molecular Cancer Therapeutics. 21:184-192
Pancreatic cancer is the third most common cause of cancer-related deaths in the United States. Although gemcitabine is the standard of care for most patients with pancreatic cancer, its efficacy is limited by the development of resistance. This resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f90c718fcbc10ffba1fbdd29a49ea02
https://doi.org/10.1158/1535-7163.mct-21-0474
https://doi.org/10.1158/1535-7163.mct-21-0474
Autor:
Gregory J. Anderson, Daniel F. Wallace, Elise S. Pelzer, Brie K. Fuqua, Chris D. Vulpe, Sheridan L. Helman, David M. Frazer, Sarah J. Wilkins, Anthony V. Perkins, Page E Whibley, David G. Simmons, Jessica L. O’Callaghan, James S. M. Cuffe, Daniel R. McKeating
Publikováno v:
The Journal of Nutrition. 151:2541-2550
BACKGROUND: The ferroxidase zyklopen (Zp) has been implicated in the placental transfer of iron to the fetus. However, the evidence for this is largely circumstantial. OBJECTIVES: This study aimed to determine whether Zp is essential for placental ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5600556b964f8c239039c41aef5615cd
https://doi.org/10.1093/jn/nxab174
https://doi.org/10.1093/jn/nxab174
Autor:
Bin Liu, Ariana M Figueroa, Abderrahmane Tagmount, Sara T. Humes, Alex Loguinov, Chris D. Vulpe, Ping Zhang, Tara Sabo-Attwood, Max Russo, John A. Lednicky
Publikováno v:
Toxicological Sciences. 182:260-274
Organochlorine pesticides (OCPs) are persistent pollutants linked to diverse adverse health outcomes. Environmental exposure to OCPs has been suggested to negatively impact the immune system but their effects on cellular antiviral responses remain un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe11a02ff7aedceb3a84cd109b47bfa
https://doi.org/10.1093/toxsci/kfab064
https://doi.org/10.1093/toxsci/kfab064
Autor:
Nam H.K. Nguyen, Abderrahmane Tagmount, Jeffrey E. Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Stanley B. Pounds, Chris D. Vulpe, Jatinder K. Lamba
Publikováno v:
Blood. 140:5947-5948
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4c102d26ba2c4e125ad521583aca8b
https://doi.org/10.1182/blood-2022-159322
https://doi.org/10.1182/blood-2022-159322