Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Chris Coleclough"'
Autor:
Ruth Ann Scroggs, Xiaoyan Zhan, Julia L. Hurwitz, Kelli L. Boyd, Cecilia Prouser, Sateesh Krishnamurthy, Allen Portner, Chris Coleclough, Brita Brown, Karen S. Slobod, Toru Takimoto
Publikováno v:
Viral Immunology. 18:255-266
Respiratory syncytial virus (RSV) is among the most important and serious pediatric respiratory diseases, and yet after more than four decades of research an effective vaccine is still unavailable. This review examines the role of the immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a17dc7a3a8c2ad14046d39b2f4474cf
https://doi.org/10.1089/vim.2005.18.255
https://doi.org/10.1089/vim.2005.18.255
Autor:
Amy Zirkel, Brita Brown, Timothy D. Lockey, Julia L. Hurwitz, Peter C. Doherty, Robert E. Sealy, Karen S. Slobod, Xiaoyan Zhan, Pamela Freiden, Louis N. Martin, John Stambas, Bart G. Jones, Mattia Bonsignori, James Blanchard, Sherri L. Surman, Chris Coleclough, Scott A. Brown
Publikováno v:
Current HIV Research. 3:107-112
A central obstacle to the design of a global HIV vaccine is viral diversity. Antigenic differences in envelope proteins result in distinct HIV serotypes, operationally defined such that antibodies raised against envelope molecules from one serotype w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e120a5242e8f9374eb1fb157845bbe0d
https://doi.org/10.2174/1570162053506928
https://doi.org/10.2174/1570162053506928
Autor:
Xiaoyan Zhan, Julia L. Hurwitz, Sateesh Krishnamurthy, Toru Takimoto, Ruth Ann Scroggs, Cecilia Prouser, Brita Brown, Yoshiyuki Nagai, Allen Portner, Karen S. Slobod, Chris Coleclough, Kelli L. Boyd
Publikováno v:
Journal of Virology. 78:6043-6047
Although RSV causes serious pediatric respiratory disease, an effective vaccine does not exist. To capture the strengths of a live virus vaccine, we have used the murine parainfluenza virus type 1 (Sendai virus [SV]) as a xenogeneic vector to deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb49ad80e7f918d000675d37424c312
https://doi.org/10.1128/jvi.78.11.6043-6047.2004
https://doi.org/10.1128/jvi.78.11.6043-6047.2004
Autor:
Chris Coleclough, Xiaoyan Zhan, Julia L. Hurwitz, Karen S. Slobod, Scott A. Brown, Sherri L. Surman
Publikováno v:
Vaccine. 22:1206-1213
HIV has thus far evaded control by vaccines, in part due to the high diversity among viral isolates. To effectively target HIV diversity, we propose that multi-envelope HIV vaccines should be designed. We hypothesize that minor components of complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961d8aa3d281b0f6b88b3566099f5278
https://doi.org/10.1016/j.vaccine.2003.09.028
https://doi.org/10.1016/j.vaccine.2003.09.028
Autor:
Stephen W. White, Peter C. Doherty, Amy Zirkel, Sherri L. Surman, Xiaoyan Zhan, Julia L. Hurwitz, Karen S. Slobod, Scott A. Brown, Chris Coleclough, John Stambas
Publikováno v:
The Journal of Immunology. 171:4140-4148
A long-standing question in the field of immunology concerns the factors that contribute to Th cell epitope immunodominance. For a number of viral membrane proteins, Th cell epitopes are localized to exposed protein surfaces, often overlapping with A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecd3fc55be3bfb212c4f0688765aac4
https://doi.org/10.4049/jimmunol.171.8.4140
https://doi.org/10.4049/jimmunol.171.8.4140
Autor:
Karen S. Slobod, Timothy D. Lockey, Peter C. Doherty, Chris Coleclough, Sherri L. Surman, Scott A. Brown, Xiaoyan Zhan, Julia L. Hurwitz
Publikováno v:
Journal of Virology. 77:4231-4236
Single-envelope human immunodeficiency virus (HIV) vaccines have been studied for more than a decade, with some successes in homologous challenge experiments in nonhuman primates but with no clear successes in clinical trials. To gain insight into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3962a418ac3f389b7ebda1c4565a8ff7
https://doi.org/10.1128/jvi.77.7.4231-4236.2003
https://doi.org/10.1128/jvi.77.7.4231-4236.2003
Autor:
Xiaoyan Zhan, Scott A. Brown, James Blanchard, Robert E. Sealy, Karen S. Slobod, Chris Coleclough, Mattia Bonsignori, Timothy D. Lockey, John Stambas, Julia L. Hurwitz, Louis N. Martin
Publikováno v:
Vaccine. 23(46-47)
A central obstacle to the design of a global HIV-1 vaccine is virus diversity. Pathogen diversity is not unique to HIV-1, and has been successfully conquered in other fields by the creation of vaccine cocktails. Here we describe the testing of an HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00234960a3a8e0e6432c399e4d7c98a0
https://pubmed.ncbi.nlm.nih.gov/16095768
https://pubmed.ncbi.nlm.nih.gov/16095768
Autor:
Clive A. Slaughter, Karen S. Slobod, Amy Zirkel, Scott A. Brown, Timothy D. Lockey, Peter C. Doherty, Ashutosh Mishra, Sherri L. Surman, Julia L. Hurwitz, Chris Coleclough, Vishwajeeth Pagala
Publikováno v:
AIDS research and human retroviruses. 21(2)
Our previous work has shown that immunodominant T-helper cell epitopes cluster within distinct fragments on a single face of the HIV envelope gp120 protein. We show in this report that the general positions of immunodominant epitopes are shared by T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd37b980d335eeb788d8a7b717f7a08a
https://pubmed.ncbi.nlm.nih.gov/15725756
https://pubmed.ncbi.nlm.nih.gov/15725756
Autor:
Kim J Allison, Jorge Luján-Zilbermann, Allen Portner, Chris Coleclough, Julia L. Hurwitz, Karen S. Slobod, Ruth Ann Scroggs, Brita Brown, Jerry L. Shenep
Publikováno v:
Vaccine. 22(23-24)
Human parainfluenza virus-type 1 (hPIV-1) is the most common cause of pediatric laryngotracheobronchitis (croup) and results in close to 30,000 US hospitalizations each year [Ped. Inf. Dis. J. 20 (2001) 646]. No effective vaccine is available. We exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61b20f4191397029944e28a441b098e
https://pubmed.ncbi.nlm.nih.gov/15297072
https://pubmed.ncbi.nlm.nih.gov/15297072
Autor:
Xiaoyan Zhan, Julia L. Hurwitz, John Stambas, Bart G. Jones, Chris Coleclough, Karen S. Slobod, Robert E. Sealy, Brita Brown, Sherri L. Surman, Mattia Bonsignori, Amy Zirkel, Pamela Freiden, Scott A. Brown
Publikováno v:
AIDS Research and Therapy
AIDS Research and Therapy, Vol 2, Iss 1, p 3 (2005)
AIDS Research and Therapy, Vol 2, Iss 1, p 3 (2005)
Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4163c619b1809cef25504785cdba7d5b
http://europepmc.org/articles/PMC1112584
http://europepmc.org/articles/PMC1112584