Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chris C -S Hsiung"'
Autor:
Cheryl A Keller, Alexander Q Wixom, Elisabeth F Heuston, Belinda Giardine, Chris C -S Hsiung, Maria R Long, Amber Miller, Stacie M Anderson, April Cockburn, Gerd A Blobel, David M Bodine, Ross C Hardison
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
AbstractChromatin immunoprecipitation followed by massively parallel, high throughput sequencing (ChIP-seq) is the method of choice for genome-wide identification of DNA segments bound by specific transcription factors or in chromatin with particular
Externí odkaz:
https://doaj.org/article/187ad77994884baf9b47056148b28010
Autor:
Stacie M. Anderson, Gerd A. Blobel, Maria R. Long, Belinda Giardine, April Cockburn, Alexander Q. Wixom, Chris C.-S. Hsiung, Ross C. Hardison, David M. Bodine, Elisabeth F. Heuston, Cheryl A. Keller, Amber Miller
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Chromatin immunoprecipitation followed by massively parallel, high throughput sequencing (ChIP-seq) is the method of choice for genome-wide identification of DNA segments bound by specific transcription factors or in chromatin with particular histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3724774361b255cbd598fb8434f47a92
https://doi.org/10.1093/g3journal/jkab101
https://doi.org/10.1093/g3journal/jkab101
Publikováno v:
Molecular Cell. 62:237-247
Mammalian genes do not transcribe RNA continuously but in bursts. Transcriptional output can be modulated by altering burst fraction or burst size, but how regulatory elements control bursting parameters remains unclear. Single-molecule RNA FISH expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e022e89488bfdd5578007fb5d007d0a4
https://doi.org/10.1016/j.molcel.2016.03.007
https://doi.org/10.1016/j.molcel.2016.03.007
Autor:
Simone Sidoli, Gerd A. Blobel, Chris C.-S. Hsiung, Aaron J. Stonestrom, Belinda Giardine, Cheryl A. Keller, Vivek Behera, Nicole Hamagami, Natarajan V. Bhanu, Hongxin Wang, Michael T. Werner, Benjamin A. Garcia, Zuo-Fei Yuan, Ross C. Hardison
Publikováno v:
Cell reports
Cell Reports, Vol 27, Iss 2, Pp 400-415.e5 (2019)
Cell Reports, Vol 27, Iss 2, Pp 400-415.e5 (2019)
In Brief Chromatin reader protein BRD4 is thought to bookmark mitotic chromatin to propagate transcriptional states across mitosis. Behera et al. profiled and perturbed mitotic BRD4 chromatin occupancy to show that BRD4 is dispensable for this proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649f958d85ffb14bc5daadeea552d3ac
https://pubmed.ncbi.nlm.nih.gov/30970245
https://pubmed.ncbi.nlm.nih.gov/30970245
Autor:
Songjoon Baek, Belinda Giardine, Maheshi Udugama, Ross C. Hardison, Gerd A. Blobel, Cheryl A. Keller, Chris C.-S. Hsiung, Christopher L. Frank, Myong-Hee Sung, Gregory E. Crawford, Christapher S. Morrissey
Publikováno v:
Genome Research. 25:213-225
Mitosis entails global alterations to chromosome structure and nuclear architecture, concomitant with transient silencing of transcription. How cells transmit transcriptional states through mitosis remains incompletely understood. While many nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834805ce5842c4e9f6deeabfabc117ed
https://doi.org/10.1101/gr.180646.114
https://doi.org/10.1101/gr.180646.114
Autor:
Laavanya Sankaranarayanan, Peng Huang, Paul Ginart, Aaron J. Stonestrom, Ross C. Hardison, Carolyne J. Face, Caroline Bartman, Cheryl A. Keller, Kristen S. Jahn, Chris C.-S. Hsiung, Belinda Giardine, Arjun Raj, Perry Evans, Gerd A. Blobel
During mitosis, RNA polymerase II (Pol II) and many transcription factors dissociate from chromatin, and transcription ceases globally. Transcription is known to restart in bulk by telophase, but whether de novo transcription at the mitosis–G1 tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e1e0e4c7ed48bc3709b4a3017d8a29
https://europepmc.org/articles/PMC4926865/
https://europepmc.org/articles/PMC4926865/
Enhancers govern transcription through multiple mechanisms, including the regulation of elongation by RNA polymerase II (RNAPII). We characterized the dynamics of looped enhancer contacts during synchronous transcription elongation. We found that two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27447dd466933d1d52d37747d9769f87
https://europepmc.org/articles/PMC4604340/
https://europepmc.org/articles/PMC4604340/
Autor:
Chris C.-S. Hsiung, Gerd A. Blobel
Publikováno v:
Nature Cell Biology. 18:1124-1125
Embryonic stem cells maintain pluripotency through countless mitoses. A recent report shows that the transcription factor Esrrb remains bound to chromatin during mitosis, including at regulatory regions that support pluripotency. Mitotic chromatin oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a6bbe3f66a63b026fc4842d31b645c
https://doi.org/10.1038/ncb3432
https://doi.org/10.1038/ncb3432
Autor:
Adam Bagg, Selina M. Luger, Priya Velu, Kiarash Salafian, Chris C.-S. Hsiung, Jennifer J.D. Morrissette
Publikováno v:
Blood. 128:2866-2866
Introduction: Clonal myeloid malignancies such as AML are often characterized and treated based on specific mutation profiles identified at diagnosis. Routine use of clinical cancer next-generation sequencing (NGS) in diagnosis and disease monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c79a7ec23fee9cd7885eda1141bd9ca6
https://doi.org/10.1182/blood.v128.22.2866.2866
https://doi.org/10.1182/blood.v128.22.2866.2866
Publikováno v:
BioTechniques. 56(2)
Mitosis entails complex chromatin changes that have garnered increasing interest from biologists who study genome structure and regulation—fields that are being advanced by high-throughput sequencing (Seq) technologies. The application of these tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee983f982b8dac37abd878d8f32c482
https://pubmed.ncbi.nlm.nih.gov/24502799
https://pubmed.ncbi.nlm.nih.gov/24502799