Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chris Bielow"'
Autor:
Adam W. Whisnant, Christopher S. Jürges, Thomas Hennig, Emanuel Wyler, Bhupesh Prusty, Andrzej J. Rutkowski, Anne L’hernault, Lara Djakovic, Margarete Göbel, Kristina Döring, Jennifer Menegatti, Robin Antrobus, Nicholas J. Matheson, Florian W. H. Künzig, Guido Mastrobuoni, Chris Bielow, Stefan Kempa, Chunguang Liang, Thomas Dandekar, Ralf Zimmer, Markus Landthaler, Friedrich Grässer, Paul J. Lehner, Caroline C. Friedel, Florian Erhard, Lars Dölken
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here, using computational integration of multi-omics data, the authors provide a detailed transcriptome and translatome of herpes simplex virus 1 (HSV-1), including previously unidentified ORFs and N-terminal extensions. The study also provides a HSV
Externí odkaz:
https://doaj.org/article/2bc69e036d254f1f89647997e0dbd0b2
Autor:
Sascha Bulik, Thorsten Cramer, Athanassios Fragoulis, Stefan Kempa, Nikolaus Berndt, Guido Mastrobuoni, Hermann-Georg Holzhütter, Steven W.M. Olde Damink, Aurelien Dugourd, Olga Vvedenskaya, Matthias Pietzke, Antje Egners, Chris Bielow, Rob J.J. van Gassel, Julio Saez-Rodriguez, Merve Erdem
Publikováno v:
British journal of cancer : BJC 122(2), 233-244 (2020). doi:10.1038/s41416-019-0659-3 special issue: "Cancer Metabolism"
British Journal of Cancer
British Journal of Cancer, 122(2), 233-244. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer, 122(2), 233-244. Nature Publishing Group
Background Metabolic alterations can serve as targets for diagnosis and cancer therapy. Due to the highly complex regulation of cellular metabolism, definite identification of metabolic pathway alterations remains challenging and requires sophisticat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78df8ae591f16ec46b90fe1e4ef8ce05
Publikováno v:
Analytical Chemistry. 89:2986-2994
Mass-spectrometry-based lipidomics aims to identify as many lipid species as possible from complex biological samples. Due to the large combinatorial search space, unambiguous identification of lipid species is far from trivial. Mass ambiguities are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b1199e8709a092f3e22471ac29142e
https://doi.org/10.1021/acs.analchem.6b04456
https://doi.org/10.1021/acs.analchem.6b04456
Autor:
Florian W. H. Künzig, Thomas Hennig, Markus Landthaler, Paul J. Lehner, Stefan Kempa, Chunguang Liang, Caroline C. Friedel, Christopher S. Jürges, Thomas Dandekar, Florian Erhard, Margarete Göbel, Robin Antrobus, Adam W. Whisnant, Emanuel Wyler, Kristina Döring, Lars Dölken, Chris Bielow, Bhupesh K. Prusty, Anne L’Hernault, Ralf Zimmer, Nicholas J Matheson, Friedrich A. Grässer, Jennifer Menegatti, Guido Mastrobuoni, Andrzej J. Rutkowski
SummarySince the genome of herpes simplex virus 1 (HSV-1) was first sequenced more than 30 years ago, its predicted 80 genes have been intensively studied. Here, we unravel the complete viral transcriptome and translatome during lytic infection with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f611cb225490ef6d491008256de7d4f5
https://doi.org/10.1101/603654
https://doi.org/10.1101/603654
Publikováno v:
Journal of Chromatography A. 1371:196-203
Levothyroxine as active pharmaceutical ingredient of formulations used for the treatment of hypothyroidism is distributed worldwide and taken by millions of people. An important issue in terms of compound stability is its capability to react with amb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329135fe29aac0765eaf6d5f0cf27bee
https://doi.org/10.1016/j.chroma.2014.10.071
https://doi.org/10.1016/j.chroma.2014.10.071
Autor:
Peter Schneider, Hermann Stuppner, Christian G. Huber, Chris Bielow, Ralf Braun, Volker Neu, Knut Reinert
Publikováno v:
Nachrichten aus der Chemie. 61:455-458
Ultrahochleistungs-Flussigchromatographie und hochauflosende Massenspektrometrie geben neue und detaillierte Einblicke in die Zusammensetzung synthetischer pharmazeutischer Wirkstoffe. Die Gerate detektieren Spuren von Verunreinigungen und Abbauprodu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24b2495ffb257c4dad274bb9ac3ed413
https://doi.org/10.1002/nadc.201390135
https://doi.org/10.1002/nadc.201390135
Publikováno v:
Molecular & Cellular Proteomics; Vol 12
Molecular & Cellular Proteomics
Molecular & Cellular Proteomics
The increasing scale and complexity of quantitative proteomics studies complicate subsequent analysis of the acquired data. Untargeted label-free quantification, based either on feature intensities or on spectral counting, is a method that scales par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315e7572d9913db521c2426e7cd6830a
https://doi.org/10.1074/mcp.r112.025163
https://doi.org/10.1074/mcp.r112.025163
Autor:
Volker Neu, Hermann Stuppner, Iris Gostomski, Peter Schneider, Reiner Wintringer, Chris Bielow, Knut Reinert, Ralf Braun, Christian G. Huber
Publikováno v:
Analytical Chemistry. 85:3309-3317
Rapid and efficient quality control according to the public authority regulations is mandatory to guarantee safety of the pharmaceuticals and to save resources in the pharmaceutical industry. In the case of so-called "grandfather products" like the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c0f13630d49ae85137a7bfe3ac3b99
https://doi.org/10.1021/ac303722j
https://doi.org/10.1021/ac303722j
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research; Vol 11
Journal of Proteome Research; Vol 11
Mass spectrometry coupled to high-performance liquid chromatography (HPLC-MS) is evolving more quickly than ever. A wide range of different instrument types and experimental setups are commonly used. Modern instruments acquire huge amounts of data, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934827ab5e5ec16203fdc3ca4c6a8ee6
https://doi.org/10.1021/pr300187f
https://doi.org/10.1021/pr300187f
Publikováno v:
Journal of proteome research. 15(3)
Mass spectrometry-based proteomics coupled to liquid chromatography has matured into an automatized, high-throughput technology, producing data on the scale of multiple gigabytes per instrument per day. Consequently, an automated quality control (QC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793f777db6934bc13b3aeb97c7ab2ea1
https://pubmed.ncbi.nlm.nih.gov/26653327
https://pubmed.ncbi.nlm.nih.gov/26653327