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pro vyhledávání: '"Chris Belisle"'
Autor:
Chris Belisle, Dongyoun Jang, Mark A. Snyder, Mayank Vats, Xuan Han, Sushmita Koley, Steven M. Cramer, Scott H. Altern
Publikováno v:
Journal of chromatography. A. 1653
In this paper, we examined the chromatographic behavior of a new class of guanidine-based multimodal anion exchange resins. The selectivities and protein recoveries on these resins were first evaluated using linear gradient chromatography with a mode
Autor:
Chris Belisle, Mark A. Snyder, Hong Chen, Julie Robinson, Yueping Xu, Steven M. Cramer, Jia-Li Liao, He Xuemei
Publikováno v:
Journal of Chromatography A. 1569:101-109
The increasing prevalence of low pI non-mAb therapeutics as well as current challenges in mAb-aggregate separations and low recoveries motivate further development in the multimodal anion exchange (MM AEX) space. In this work, linear salt gradient ex