Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Chris Barnes"'
Autor:
Jin Hui Teh, Ala Amgheib, Ruisi Fu, Chris Barnes, Joel Abrahams, Ali Ashek, Ning Wang, Zixuan Yang, Muneera Mansoorudeen, Nicholas J. Long, Eric O. Aboagye
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1915 (2023)
C-Met is a receptor tyrosine kinase that is overexpressed in a range of different cancer types, and has been identified as a potential biomarker for cancer imaging and therapy. Previously, a 68Ga-labelled peptide, [68Ga]Ga-EMP-100, has shown promise
Externí odkaz:
https://doaj.org/article/4cbc9b3ccfed4e6b8e772595ea7ef2b4
Publikováno v:
Frontiers in Sports and Active Living, Vol 4 (2022)
Relative age selection bias persists within all major soccer leagues and youth soccer academies across the globe, with the relative age effect (RAE) being typically characterized as the over selection of relatively older players (who have sometimes a
Externí odkaz:
https://doaj.org/article/1e0bfdb14dc64feba490d68746dc9144
Autor:
Anthony K. Chan, Jayanthi Alamelu, Chris Barnes, Ampaiwan Chuansumrit, May‐Lill Garly, Rikke Medom Meldgaard, Guy Young
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1101-1113 (2020)
Abstract Background/Objective We report the first analysis of an extended half‐life recombinant factor IX, nonacog beta pegol (N9‐GP), in previously untreated patients (PUPs) and minimally treated patients with hemophilia B. Methods Paradigm 6 (S
Externí odkaz:
https://doaj.org/article/9d21f64616344e6c8eaa8aafa8249a71
Autor:
Louis Allott, Diana Brickute, Cen Chen, Marta Braga, Chris Barnes, Ning Wang, Eric O. Aboagye
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-17 (2020)
Abstract Background Glycogen is a multibranched polysaccharide of glucose produced by cells to store energy and plays a key role in cancer. A previously reported fluorescent probe (CDg4) was shown to selectively bind glycogen in mouse embryonic stem
Externí odkaz:
https://doaj.org/article/639eef8041cd4290b1ce5944d1549f8c
Autor:
Vessela Vassileva, Stephen M. Stribbling, Chris Barnes, Laurence Carroll, Marta Braga, Joel Abrahams, Kathrin Heinzmann, Caroline Haegeman, Marion MacFarlane, Kathryn L. Simpson, Caroline Dive, Jamie Honeychurch, Timothy M. Illidge, Eric O. Aboagye
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Purpose We have previously developed the caspase-based radiotracer, 18F-ICMT-11, for PET imaging to monitor treatment response. We further validated 18F-ICMT-11 specificity in a murine melanoma death-switch tumour model with conditional acti
Externí odkaz:
https://doaj.org/article/88f942a294f14bd991354aaa6efc2563
Publikováno v:
Urban Transcripts, Vol 4, Iss 1 (2021)
Annual CO2 emissions are now 45% higher than they were at the dawn of the millennium and 500% higher than the 1950s. Carbon emissions from the richest 1% more than double the emissions of the poorest half of humanity. Scientists warn of “untold hum
Externí odkaz:
https://doaj.org/article/ed85f18a009c417eb23c7b2b2d5e0757
Autor:
Chris Barnes, Yiorgos Papamanousakis
Publikováno v:
Urban Transcripts, Vol 3, Iss 3 (2020)
“What is well known, precisely because it is well known, is not known. In the knowledge process, the commonest way to mislead oneself and others is to assume that something is well known and to accept it as such.” – Hegel, Phenomenology of Spir
Externí odkaz:
https://doaj.org/article/6b76af9b1f974072b627bfcf282ed698
Autor:
Yunqing Li, Marianna Inglese, Suraiya Dubash, Chris Barnes, Diana Brickute, Marta Costa Braga, Ning Wang, Alice Beckley, Kathrin Heinzmann, Louis Allott, Haonan Lu, Cen Chen, Ruisi Fu, Laurence Carroll, Eric O. Aboagye
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1246 (2021)
Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotr
Externí odkaz:
https://doaj.org/article/d45310b8a4984fdbbf4cf37c689fdb94
Autor:
Vessela Vassileva, Marta Braga, Chris Barnes, Justyna Przystal, Ali Ashek, Louis Allott, Diana Brickute, Joel Abrahams, Keittisak Suwan, Angel M. Carcaboso, Amin Hajitou, Eric O. Aboagye
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 811 (2021)
Background: Reprogrammed cellular metabolism is a cancer hallmark. In addition to increased glycolysis, the oxidation of acetate in the citric acid cycle is another common metabolic phenotype. We have recently developed a novel fluorine-18-labelled t
Externí odkaz:
https://doaj.org/article/827fd890bd0147e8ae477a6ac547696d
Autor:
Ning Wang, Diana Brickute, Marta Braga, Chris Barnes, Haonan Lu, Louis Allott, Eric O. Aboagye
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1078 (2021)
Choline kinase alpha (CHKA) is a promising target for the development of cancer therapeutics. We have previously reported ICL-CCIC-0019, a potent CHKA inhibitor with high cellular activity but with some unfavorable pharmacological properties. In this
Externí odkaz:
https://doaj.org/article/71e7397d4fe841c29cfd8b0878c1ad76