Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Chris Albanese"'
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-20 (2022)
Abstract Cancer is a heterogeneous disease with multifaceted drug resistance mechanisms (e.g., tumour microenvironment [TME], tumour heterogeneity, and immune evasion). Natural products are interesting repository of bioactive molecules, especially th
Externí odkaz:
https://doaj.org/article/da9bcf0f9fdf40aba2d55dd976b2d43b
Autor:
Jedson R. Liggett, Jiman Kang, Suman Ranjit, Olga Rodriguez, Katrina Loh, Digvijay Patil, Yuki Cui, Anju Duttargi, Sang Nguyen, Britney He, Yichien Lee, Kesha Oza, Brett S. Frank, DongHyang Kwon, Heng-Hong Li, Bhaskar Kallakury, Andrew Libby, Moshe Levi, Simon C. Robson, Thomas M. Fishbein, Wanxing Cui, Chris Albanese, Khalid Khan, Alexander Kroemer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type 1 Natural Killer T-cells (NKT1 cells) play a critical role in mediating hepatic ischemia-reperfusion injury (IRI). Although hepatic steatosis is a major risk factor for preservation type injury, how NKT cells impact this is understudied. Given N
Externí odkaz:
https://doaj.org/article/2dba904857b84f9d8242e4172fdade09
Autor:
Heba R. Al Refaey, Al-Sayeda A. Newairy, Mayssaa M. Wahby, Chris Albanese, Mohamed Elkewedi, Muhammad Umer Choudhry, Ahmed S. Sultan
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-16 (2021)
Abstract Background Recently, there is increasing awareness focused on the identification of naturally occurring anticancer agents derived from natural products. Manuka honey (MH) has been recognized for its biological properties as antimicrobial, an
Externí odkaz:
https://doaj.org/article/8fe1208dabda4a279b44fe86bdf4e23c
Autor:
Neel D. Trivedi, Samantha Armstrong, Hongkun Wang, Marion Hartley, John Deeken, A. Ruth He, Deepa Subramaniam, Heather Melville, Chris Albanese, John L. Marshall, Jimmy Hwang, Michael J. Pishvaian
Publikováno v:
Cancer Medicine, Vol 10, Iss 6, Pp 1944-1954 (2021)
ABSTRACT Background Temsirolimus is an mTOR antagonist with proven anticancer efficacy. Preclinical data suggest greater anticancer effect when mTOR inhibitors are combined with cytotoxic chemotherapy. We performed a Phase I assessment of the combina
Externí odkaz:
https://doaj.org/article/f18add4e627d4d0ea61548ba2ddd4099
Autor:
Yichien Lee, Olga C. Rodriguez, Chris Albanese, Victor Rodrigues Santos, José Antônio Cortes de Oliveira, Ana Luiza Ferreira Donatti, Artur Fernandes, Norberto Garcia-Cairasco, Prosper N'Gouemo, Patrick A. Forcelli
Publikováno v:
Neurobiology of Disease, Vol 111, Iss , Pp 80-90 (2018)
Acoustically evoked seizures (e.g., audiogenic seizures or AGS) are common in models of inherited epilepsy and occur in a variety of species including rat, mouse, and hamster. Two models that have been particularly well studied are the genetically ep
Externí odkaz:
https://doaj.org/article/1f529bfae11e46aeaaa5322ba326e875
Autor:
Christopher R. Heier, Jesse M. Damsker, Qing Yu, Blythe C. Dillingham, Tony Huynh, Jack H. Van der Meulen, Arpana Sali, Brittany K. Miller, Aditi Phadke, Luana Scheffer, James Quinn, Kathleen Tatem, Sarah Jordan, Sherry Dadgar, Olga C. Rodriguez, Chris Albanese, Michael Calhoun, Heather Gordish‐Dressman, Jyoti K. Jaiswal, Edward M. Connor, John M. McCall, Eric P. Hoffman, Erica K. M. Reeves, Kanneboyina Nagaraju
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 10, Pp 1569-1585 (2013)
Abstract Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular b
Externí odkaz:
https://doaj.org/article/dcba462e544f48e9928e39d69ca7d000
Autor:
Fnu Nagajyothi, Mahalia S Desruisseaux, Louis M Weiss, Streamson Chua, Chris Albanese, Fabiana S Machado, Lisia Esper, Michael P Lisanti, Mauro M Teixeira, Philipp E Scherer, Herbert B Tanowitz
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Pp 219-225 (2009)
Trypanosoma cruzi infection of the adipose tissue of mice triggers the local expression of inflammatory mediators and a reduction in the expression of the adipokine adiponectin. T. cruzi can be detected in adipose tissue by PCR 300 days post-infectio
Externí odkaz:
https://doaj.org/article/31b4193e3c584e4dbf4ba8052ec93fb0
Autor:
Claire B Pollock, Yuzhi Yin, Hongyan Yuan, Xiao Zeng, Sruthi King, Xin Li, Levy Kopelovich, Chris Albanese, Robert I Glazer
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16215 (2011)
Peroxisome proliferator-activated receptorδ (PPARδ) is a transcription factor that is associated with metabolic gene regulation and inflammation. It has been implicated in tumor promotion and in the regulation of 3-phosphoinositide-dependent kinase
Externí odkaz:
https://doaj.org/article/5fca850da31c4dfc987a93a0d1a5b190
Autor:
Claire B. Pollock, Olga Rodriguez, Philip L. Martin, Chris Albanese, Xin Li, Levy Kopelovich, Robert I. Glazer
Publikováno v:
PPAR Research, Vol 2010 (2010)
Peroxisome proliferator-activated receptorδ (PPARδ) regulates a multiplicity of physiological processes associated with glucose and lipid metabolism, inflammation, and proliferation. One or more of these processes likely create risk factors associa
Externí odkaz:
https://doaj.org/article/88b51a38a8d74c59855dc92b40531fb3
Autor:
Lauren M. Rosko, Tyler Gentile, Victoria N. Smith, Zeeba Manavi, George S. Melchor, Jingwen Hu, Nataliia V. Shults, Chris Albanese, Yichien Lee, Olga Rodriguez, Jeffrey K. Huang
Publikováno v:
The Journal of Neuroscience. 43:1143-1153
Cerebral creatine deficiency syndrome (CCDS) is an inborn error of metabolism characterized by intellectual delays, seizures, and autistic-like behavior. However, the role of endogenously synthesized creatine on CNS development and function remains p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7091c23d026d57f9e33379366756fd16
https://doi.org/10.1523/jneurosci.2120-21.2022
https://doi.org/10.1523/jneurosci.2120-21.2022