Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chris A. Nasrallah"'
Publikováno v:
Molecular Biology and Evolution
Paired epistatic interactions, such as those in the stem regions of RNA, play an important role in many biological processes. However, unlike protein-coding regions, paired epistatic interactions have lacked the appropriate statistical tools for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01780ba6ffdfca8eb4ee8b6aee67775b
https://doi.org/10.1093/molbev/mst108
https://doi.org/10.1093/molbev/mst108
Publikováno v:
Systematic Biology
Nearly all commonly used methods of phylogenetic inference assume that characters in an alignment evolve independently of one another. This assumption is attractive for simplicity and computational tractability but is not biologically reasonable for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b949cfa7e4435fed9e76a5c1f2e0cfdb
https://doi.org/10.1093/sysbio/syq074
https://doi.org/10.1093/sysbio/syq074
Autor:
Melanie J. McConnell, Tamer E. Fandy, Steven D. Gore, James G. Herman, Yezou Sun, Patrick Kerns, Hetty E. Carraway, Elizabeth A. Sugar, Allen S. Yang, Ibitayo Owoeye, Si Ho Choi, Katharine Oteiza, Lewis R. Silverman, Timothy Aucott, Jonathan D. Licht, Marianne K.H. Kim, Chris A. Nasrallah, Anchalee Jiemjit, Weijia Zhang, Igor Espinoza-Delgado, Tianna Dauses, Anthony J. Murgo, Rosalie Odchimar-Reissig
Publikováno v:
Blood. 114:2764-2773
Sequential administration of DNA methyltransferase (DNMT) inhibitors and histone deacetylase (HDAC) inhibitors has demonstrated clinical efficacy in patients with hematologic malignancies. However, the mechanism behind their clinical efficacy remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8101afc68b5d10749cdfbe79040f91
https://doi.org/10.1182/blood-2009-02-203547
https://doi.org/10.1182/blood-2009-02-203547
Publikováno v:
Cell Cycle. 4:1774-1782
Physiological polyploidy is a characteristic of several cell types including the megakaryocytes (MK) that give rise to circulating blood platelets. MK achieve polyploidy by switching from a normal to an endomitotic cell cycle characterized by the abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675b8f8e90d3a1451743d405166a53fd
https://doi.org/10.4161/cc.4.12.2171
https://doi.org/10.4161/cc.4.12.2171
Autor:
Chris A. Nasrallah
Publikováno v:
BMC Bioinformatics
The role of epistatic interactions among loci is a central question in evolutionary biology and is increasingly relevant in the genomic age. While the population genetics of compensatory substitution have received considerable attention, most studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77cbaae551b7bdaa6d5c5d621f887a9
