Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Choy-Pik Chiu"'
Publikováno v:
Cell Transplantation, Vol 12 (2003)
Use of human hepatocytes for therapeutic and drug discovery applications is hampered by limited tissue source and the inability of hepatocytes to proliferate and maintain function long term in vitro. Human embryonic stem (hES) cells are immortal and
Externí odkaz:
https://doaj.org/article/be6152f4e1f3427dad4933c7c0047fd7
Autor:
FRANK LEE, CHOY-PIK CHIU, JANUSZ WIDEMAN, PHILLIP HODGKIN, SUSAN HUDAK, LOUISE TROUTT, THERESA NG, COURTNEY MOULDS, ROBERT COFFMAN, ALBERT ZLOTNIK, DONNA RENNICK
Publikováno v:
Annals of the New York Academy of Sciences. 557:215-229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::392c578285aa8a740e39bbc6b365cfef
https://doi.org/10.1111/j.1749-6632.1989.tb24015.x
https://doi.org/10.1111/j.1749-6632.1989.tb24015.x
Autor:
Thomas A. Mustoe, Calvin B. Harley, Jon E. Mogford, Shu Jen Chen, Russell R. Reid, Hakim K. Said, W. Robert Liu, Choy-Pik Chiu
Publikováno v:
Human Gene Therapy. 17:651-660
Chronic ischemic wounds are major clinical problems, and are especially prevalent in elderly patients. Management of these wounds costs billions of dollars annually in the United States. Because of the severe impairment in tissue repair, ischemic wou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2062d7f5f2e87cd1102fbc0ea92d4917
https://doi.org/10.1089/hum.2006.17.651
https://doi.org/10.1089/hum.2006.17.651
Autor:
Mahendra S. Rao, Margaret S. Inokuma, Jerrod Denham, Choy-Pik Chiu, Tahmina Mujtaba, Melissa K. Carpenter
Publikováno v:
Experimental Neurology. 172:383-397
Human embryonic stem (hES) cells proliferate and maintain their pluripotency for over a year in vitro (M. Amit, M. K. Carpenter, M. S. Inokuma, C. P. Chiu, C. P., Harris, M. A. Waknitz, J. Itskovitz-Eldor, and J. A. Thomson. 2000. Dev. Biol. 227: 271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6640570e65b3ed7a32d234164e719c83
https://doi.org/10.1006/exnr.2001.7832
https://doi.org/10.1006/exnr.2001.7832
Autor:
Philip S. Tsao, Hidetsugu Matsushita, Choy-Pik Chiu, Edwin Chang, Alexander J. Glassford, John P. Cooke
Publikováno v:
Circulation Research. 89:793-798
Advanced age is associated with endothelial dysfunction and increased risk for atherosclerosis. However, the mechanisms for these observed effects are not clear. To clarify the association between aging and loss of endothelial function, young human a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28df28ec7b35028312b88d9777fd0ae
https://doi.org/10.1161/hh2101.098443
https://doi.org/10.1161/hh2101.098443
Publikováno v:
Blood. 91:3255-3262
Telomerase is a ribonucleoprotein polymerase that synthesizes telomeric repeats onto the 3′ ends of eukaryotic chromosomes. Activation of telomerase may prevent telomeric shortening and correlates with cell immortality in the germline and certain t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c050595c5371fbe28f7ff8e35921477e
https://doi.org/10.1182/blood.v91.9.3255.3255_3255_3262
https://doi.org/10.1182/blood.v91.9.3255.3255_3255_3262
Publikováno v:
Biology of Reproduction. 56:1120-1125
Telomerase is a ribonucleoprotein that synthesizes telomeric DNA at the ends of eukaryotic chromosomes. It has been hypothesized that telomerase activity is necessary for cellular immortalization and that telomerase activity is present in cells of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58a742a565716b088a03fff8e9a4bf35
https://doi.org/10.1095/biolreprod56.5.1120
https://doi.org/10.1095/biolreprod56.5.1120
Autor:
Calvin B. Harley, Choy-Pik Chiu
Publikováno v:
Experimental Biology and Medicine. 214:99-106
Telomere shortening is correlated with cell senescence in vitro and cell aging in vivo. The telomere hypothesis suggests that telomere length serves as a mitotic clock for timing cellular replicative life span. Expression of telomerase stabilizes tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f071ab400b88abbe37eb2fcd52692c
https://doi.org/10.3181/00379727-214-44075
https://doi.org/10.3181/00379727-214-44075
Autor:
Karim F. Hirji, Bryant Villeponteau, Michael D. West, Calvin B. Harley, Janis V. Giorgi, Choy-Pik Chiu, Mary Ann Hausner, Rita B. Effros, Lili Wang, Richard C. Allsopp
Publikováno v:
AIDS. 10:F17-22
Objective : To test the hypothesis that the expanded population of non-proliferative CD28- CD8+ T cells in HIV disease have shortened telomeres, thereby providing evidence that increased rounds of CD8+ cell division occur during HIV disease, possibly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9416842c602627d77e6427cf214eb50
https://doi.org/10.1097/00002030-199607000-00001
https://doi.org/10.1097/00002030-199607000-00001
Autor:
Ramaswamy Narayanan, Kenneth Dorshkind, Kenneth S. Landreth, Debra Petitte, Linda G. Billips, Choy-Pik Chiu
Publikováno v:
Blood. 79:1185-1192
Newly formed B lymphocytes are a population of rapidly renewed cells in the bone marrow of mammals and their steady state production presumably depends on a cascade of regulatory cells and cytokines. Although considerable information has been forthco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc68d10d836c8e229194b09835ac69f
https://doi.org/10.1182/blood.v79.5.1185.1185
https://doi.org/10.1182/blood.v79.5.1185.1185