Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.

Autor: Mitchell W; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 United States., Goeminne LJE; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 United States., Tyshkovskiy A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 United States., Zhang S; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 United States., Chen JY; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 United States., Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115 United States., Pierce KA; Broad Institute of MIT and Harvard, Cambridge, MA 01241 United States., Choy AH; Broad Institute of MIT and Harvard, Cambridge, MA 01241 United States., Clish CB; Broad Institute of MIT and Harvard, Cambridge, MA 01241 United States., Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA 02115 United States., Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115 United States.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 27. Date of Electronic Publication: 2023 Nov 27.