Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chourouk Karkoutly"'
Publikováno v:
Scopus-Elsevier
It has been shown in vitro that dihydrolipoate (dl-6,8-dithioloctanoic acid) has antioxidant activity against microsomal lipid peroxidation. We tested dihydrolipoate for its neuroprotective activity using models of hypoxic and excitotoxic neuronal da
Autor:
Barbara Peruche, Josef Krieglstein, Jochen H. M. Prehn, Christine Roβberg, Chourouk Karkoutly, Cord Backhauβ, Jörg Nuglisch
Publikováno v:
European Journal of Pharmacology. 203:213-222
5-Hydroxytryptamine1A (5-HT1A) receptor agonists have been shown to inhibit the activity of hippocampal, cortical, and dorsal raphé neurons. We tested urapidil and a new 5-HT1A agonist, CM 57493 [4-(3-trifluoromethylphenyl)-1-(2-cyanoethyl)-1,2,3,6-
Autor:
Franz Ausmeier, Jörg Nuglisch, Matthias Welsch, Cord Backhauß, Jochen H. M. Prehn, Chourouk Karkoutly, Josef Krieglstein
Publikováno v:
Brain research. 630(1-2)
We have examined the significance of the serotonergic system in the pathophysiology of ischemic brain damage. Permanent occlusion of the middle cerebral artery (MCA) was performed in male NMRI mice. After 48 h, the animals received a transcardiac inj
Publikováno v:
Journal of pharmacological and toxicological methods. 27(1)
The aim of the present study was to investigate if the infarct area on the brain surface after middle cerebral artery (MCA) occlusion in the mouse is representative for the infarct volume and if this determination of brain injury can be used for scre
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 10(5)
The purpose of the present study was to investigate the neuroprotective action of nimodipine. Furthermore, the influence of nimodipine on postischemic local CBF (LCBF) was examined. Forebrain ischemia of the rat was performed for 10 min by bilateral