Is Tunisia ready for precision medicine? Challenges of medical genomics within a LMIC healthcare system.

Autor: Trabelsi N; Department of genetics, Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Faculty of Medicine of Sousse, Mohamed Qaroui St, Sousse, 4002, Tunisia., Othman H; Department of genetics, Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, 9 jubilee Road, Parktown, Johannesburg, 2193, South Africa., Bedhioufi H; Interdisciplinary Laboratory of University-Business Management (LIGUE), (LR99ES24), Higher Institute of Accounting and Business Administration (ISCAE), University of La Manouba, Manouba university campus, La Manouba, 2010, Tunisia., Chouk H; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Higher Institute of Biotechnology of Monastir, Taher Haddad St, Monastir, 5000, Tunisia., El Mabrouk H; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Higher Institute of Biotechnology of Monastir, Taher Haddad St, Monastir, 5000, Tunisia., Mahdouani M; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Higher Institute of Biotechnology of Monastir, Taher Haddad St, Monastir, 5000, Tunisia., Gribaa M; Department of genetics, Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Faculty of Medicine of Sousse, Mohamed Qaroui St, Sousse, 4002, Tunisia., Saad A; Department of genetics, Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia.; Faculty of Medicine of Sousse, Mohamed Qaroui St, Sousse, 4002, Tunisia., H'mida D; Department of genetics, Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia. dorrahmida@yahoo.fr.; Laboratory of cytogenetics, molecular genetics and reproductive biology (LR03SP02), Farhat Hached University Hospital, Ibn El Jazzar St, Sousse, 4000, Tunisia. dorrahmida@yahoo.fr.; Faculty of Medicine of Sousse, Mohamed Qaroui St, Sousse, 4002, Tunisia. dorrahmida@yahoo.fr.

Publikováno v: Journal of community genetics [J Community Genet] 2024 Aug; Vol. 15 (4), pp. 339-350. Date of Electronic Publication: 2024 Jul 31.

213 Genetic study of the largest Tunisian cohort of 15 patients with Netherton syndrome: Two new SPINK5 mutations and founder effect

Autor: Chouk, H., Mokni, S., Litaiem, N., Hammami, H., Mokni, M., Sriha, B., Saad, A., Hovnanian, A., Denguezli, M., H’Mida, D.

Publikováno v: In Journal of Investigative Dermatology December 2022 142(12) Supplement:S216-S216

Unusual facial lesions in H syndrome.

Autor: Rekik M; Dermatology Department Hedi Chaker University Hospital, Sfax University Sfax Tunisia., Bahloul E; Dermatology Department Hedi Chaker University Hospital, Sfax University Sfax Tunisia., Ben Rejeb M; Dermatology Department Farhat Hached University Hospital Sousse Tunisia., Sellami K; Dermatology Department Hedi Chaker University Hospital, Sfax University Sfax Tunisia., Charfi S; Pathological Anatomy Department Habib Bourguiba University Hospital, Sfax University Sfax Tunisia., Chouk H; Genetics Department Farhat Hached University Hospital Sousse Tunisia., Boudaouara T; Pathological Anatomy Department Habib Bourguiba University Hospital, Sfax University Sfax Tunisia., Turki H; Dermatology Department Hedi Chaker University Hospital, Sfax University Sfax Tunisia.

Publikováno v: Clinical case reports [Clin Case Rep] 2022 Jul 18; Vol. 10 (7). Date of Electronic Publication: 2022 Jul 18 (Print Publication: 2022).

Phenotypic intrafamilial variability including H syndrome and Rosai-Dorfman disease associated with the same c.1088G > A mutation in the SLC29A3 gene.

Autor: Chouk H; Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.; Human Cytogenetics, Molecular Genetics and Reproductive Biology, Department of Genetics, Farhat Hached University Hospital of Sousse, Sousse, Tunisia., Ben Rejeb M; Department of Dermatology, Farhat Hached University of Sousse, Sousse, Tunisia.; Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia., Boussofara L; Department of Dermatology, Farhat Hached University of Sousse, Sousse, Tunisia.; Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia., Elmabrouk H; Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.; Human Cytogenetics, Molecular Genetics and Reproductive Biology, Department of Genetics, Farhat Hached University Hospital of Sousse, Sousse, Tunisia., Ghariani N; Department of Dermatology, Farhat Hached University of Sousse, Sousse, Tunisia., Sriha B; Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia.; Department of Pathological Anatomy, Farhat Hached University Hospital of Sousse, Sousse, Tunisia., Saad A; Human Cytogenetics, Molecular Genetics and Reproductive Biology, Department of Genetics, Farhat Hached University Hospital of Sousse, Sousse, Tunisia.; Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia., H'Mida D; Human Cytogenetics, Molecular Genetics and Reproductive Biology, Department of Genetics, Farhat Hached University Hospital of Sousse, Sousse, Tunisia. dorrahmida@yahoo.fr.; Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia. dorrahmida@yahoo.fr., Denguezli M; Department of Dermatology, Farhat Hached University of Sousse, Sousse, Tunisia.; Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia.

Publikováno v: Human genomics [Hum Genomics] 2021 Oct 17; Vol. 15 (1), pp. 63. Date of Electronic Publication: 2021 Oct 17.

Profil épidémio-clinique et génétique des ichtyoses congénitales en Tunisie

Autor: Chouk, H., Saad, S., Gammoudi, R., El Mabrouk, H., Boussofara, L., Aounallah, A., Ghariani, N., Bellajouza, C., Saad, A., Hmida, D., Denguezli, M.

Publikováno v: In Annales de Dermatologie et de Vénéréologie December 2020 147(12) Supplement:A267-A268