Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Choudhary Harsha"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 5, Pp 313-342 (2020)
Cancer is one of the most dreadful diseases in the world with a mortality of 9.6 million annually. Despite the advances in diagnosis and treatment during the last couple of decades, it still remains a serious concern due to the limitations associated
Externí odkaz:
https://doaj.org/article/f4acd93035384289aaa12ac9fa80ed90
Autor:
Constanze Buhrmann, Aranka Brockmueller, Choudhary Harsha, Ajaikumar B. Kunnumakkara, Peter Kubatka, Bharat B. Aggarwal, Mehdi Shakibaei
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Tumor microenvironment (TME) has a pivotal impact on tumor progression, and epithelial-mesenchymal transition (EMT) is an extremely crucial initial event in the metastatic process in colorectal cancer (CRC) that is not yet fully understoo
Externí odkaz:
https://doaj.org/article/4f64a298bc2b4e3285b7d21a514f9873
Autor:
Uzini Devi Daimary, Dey Parama, Varsha Rana, Kishore Banik, Aviral Kumar, Choudhary Harsha, Ajaikumar B. Kunnumakkara
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100008- (2021)
Although chronic diseases are often caused by the perturbations in multiple cellular components involved in different biological processes, most of the approved therapeutics target a single gene/protein/pathway which makes them not as efficient as th
Externí odkaz:
https://doaj.org/article/cde3340c9a9d457592002fa54e7042a1
Autor:
Ajaikumar B. Kunnumakkara, Bethsebie L. Sailo, Kishore Banik, Choudhary Harsha, Sahdeo Prasad, Subash Chandra Gupta, Alok Chandra Bharti, Bharat B. Aggarwal
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-25 (2018)
Abstract Extensive research within the last several decades has revealed that the major risk factors for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and diet. It is now well established that t
Externí odkaz:
https://doaj.org/article/2c3f7624732c46b2ad5be2344c37c85b
Autor:
Sahu Henamayee, Kishore Banik, Bethsebie Lalduhsaki Sailo, Bano Shabnam, Choudhary Harsha, Satti Srilakshmi, Naidu VGM, Seung Ho Baek, Kwang Seok Ahn, Ajaikumar B Kunnumakkara
Publikováno v:
Molecules, Vol 25, Iss 10, p 2278 (2020)
According to the World Health Organization (WHO), cancer is the second-highest cause of mortality in the world, and it kills nearly 9.6 million people annually. Besides the fatality of the disease, poor prognosis, cost of conventional therapies, and
Externí odkaz:
https://doaj.org/article/9b7e643ec223444688c45b203456a30d
Autor:
Ajaikumar B. Kunnumakkara, Kishore Banik, Devivasha Bordoloi, Choudhary Harsha, Bethsebie L. Sailo, Ganesan Padmavathi, Nand K. Roy, Subash C. Gupta, Bharat B. Aggarwal
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Extensive research during last 2 decades has revealed that most drugs discovered today, although costs billions of dollars for discovery, and yet they are highly ineffective in their clinical response. For instance, the European Medicines Agency has
Externí odkaz:
https://doaj.org/article/1f5126b19039467386484648a2f63ae5
Autor:
Kishore Banik, Elina Khatoon, Choudhary Harsha, Varsha Rana, Dey Parama, Krishan Kumar Thakur, Anupam Bishayee, Ajaikumar B. Kunnumakkara
Publikováno v:
Phytotherapy Research. 36:1854-1883
The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or Huang-Qin, has been used as a traditional medicine for several thousand years. The roots of this plant contain bioactive compounds, such as wogonin (WOG), wogonoside,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9402383c459b37f7c3b4d52e669915
https://doi.org/10.1002/ptr.7386
https://doi.org/10.1002/ptr.7386
Autor:
Krishan Kumar Thakur, Ajaikumar B. Kunnumakkara, Choudhary Harsha, Kishore Banik, Subash C. Gupta, Elika Verma, Aviral Kumar, Gautam Sethi, Elina Khatoon
Publikováno v:
Journal of Cellular Physiology. 236:7938-7965
In recent years, triple-negative breast cancer (TNBC) has emerged as the most aggressive subtype of breast cancer and is usually associated with increased mortality worldwide. The severity of TNBC is primarily observed in younger women, with cases ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbe3d3163514f0b328ea04f997698d0
https://doi.org/10.1002/jcp.30463
https://doi.org/10.1002/jcp.30463
Autor:
Anuja Gracy Joseph, P. Sasikumar, Manojkumar K Thanathu, D.R. Sherin, Maniyamma Aswathy, Choudhary Harsha, Ajaikumar B. Kunnumakkara, Radhakrishnan Kokkuvayil Vasu, Kishore Banik, Dey Parama
Publikováno v:
ACS Pharmacology & Translational Science. 4:834-847
Triterpenoids are ubiquitously distributed secondary metabolites, primarily scrutinized as a source of medication and preventive measures for various chronic diseases. The ease of isolation and excellent pharmacological properties of triterpenoids ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3319decd99192f53a0910ddc86093f84
https://doi.org/10.1021/acsptsci.1c00011
https://doi.org/10.1021/acsptsci.1c00011
Autor:
Ajaikumar B. Kunnumakkara, Choudhary Harsha, Aviral Kumar, Xinliang Mao, Uzini Devi Daimary, Sosmitha Girisa, Dey Parama
Publikováno v:
Phytotherapy research : PTRREFERENCES. 35(12)
The last decade has seen an unprecedented rise in the prevalence of chronic diseases worldwide. Different mono-targeted approaches have been devised to treat these multigenic diseases, still most of them suffer from limited success due to the off-tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069f4971f6487b3b7e5a780eed73cfab
https://pubmed.ncbi.nlm.nih.gov/34498308
https://pubmed.ncbi.nlm.nih.gov/34498308