suppress the alternative lengthening of telomere (ALT) pathway in

Autor: Zencir, S, Hsieh, MH, Hsu, JS, Ergun, Y, Chou, GL, Li, TK, Teng, SC, Topcu, Z

Background DNA topoisomerase and telomerase enzymes are popular targets of several anti-tumor drugs. Smooth proceeding of telomeric recombination requires Topoisomerase II (Top2), which is involved in telomere-telomere recombination through functioni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3566::7781fa57831eb10ab984be1141ee16fb

Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase-negative cells.

Autor: Zencir S; Department of Molecular Biology, University of Geneva, CH-1211, Geneva 4, Switzerland. sevil.zencir@unige.ch.; Department of Medical Biology, Faculty of Medicine, Pamukkale University, 20020, Denizli, Turkey. sevil.zencir@unige.ch., Hsieh MH; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan., Hsu JS; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan., Ergun Y; Department of Chemistry, Faculty of Science, Dokuz Eylul University, 35160, Izmir, Turkey., Chou GL; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan., Li TK; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan., Teng SC; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan., Topcu Z; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Ege University, 35100, Izmir, Turkey.

Publikováno v: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2020 Jul; Vol. 146 (7), pp. 1671-1676. Date of Electronic Publication: 2020 Apr 24.

Ethanol Extract of Hedyotis diffusa Willd Affects Immune Responses in Normal Balb/c Mice In Vivo.

Autor: Kuo YJ; Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C. Department of Traditional Chinese Medicine, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C., Lin JP; School of Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C., Hsiao YT; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C., Chou GL; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C., Tsai YH; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C., Chiang SY; Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C., Lin JG; Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C. jgchung@mail.cmu.edu.tw jglin@mail.cmu.edu.tw., Chung JG; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C. Department of Biotechnology, Asia University, Taichung, Taiwan, R.O.C. jgchung@mail.cmu.edu.tw jglin@mail.cmu.edu.tw.

Publikováno v: In vivo (Athens, Greece) [In Vivo] 2015 Jul-Aug; Vol. 29 (4), pp. 453-60.