Retinyl esters form lipid droplets independently of triacylglycerol and seipin

Autor: Molenaar, Martijn R, Yadav, Kamlesh K, Toulmay, Alexandre, Wassenaar, Tsjerk A, Mari, Muriel C, Caillon, Lucie, Chorlay, Aymeric, Lukmantara, Ivan E, Haaker, Maya W, Wubbolts, Richard W, Houweling, Martin, Vaandrager, Arie Bas, Prieur, Xavier, Reggiori, Fulvio, Choudhary, Vineet, Yang, Hongyuan, Schneiter, Roger, Thiam, Abdou Rachid, Prinz, William A, Helms, J Bernd, dB&C FR-RMSC RMSC, Dep Scheikunde, Sub Biochemistry of Membranes begr1-6-12, Veterinaire biochemie, Celbiologie, IOV CCB, dB&C I&I, dB&C FR-RMSC FR

Publikováno v: The Journal of Cell Biology, 220(10):202011071. ROCKEFELLER UNIV PRESS
Journal of Cell Biology
Journal of Cell Biology, 2021, 220 (10), ⟨10.1083/jcb.202011071⟩
Journal of Cell Biology, Rockefeller University Press, 2021, 220 (10), ⟨10.1083/jcb.202011071⟩
The Journal of Cell Biology
Journal of Cell Biology, 220(10), 1. Rockefeller University Press

Molenaar et al. show that seipin does not play a role in the biogenesis of lipid droplets composed mostly or only of the neutral lipid retinyl ester, even in cells that produce triacylglycerols.
Lipid droplets store neutral lipids, primarily tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5918303642e99ebc5e72abdf8777cb
https://dspace.library.uu.nl/handle/1874/412830

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Mechanisms of protein targeting to lipid droplets: A unified cell biological and biophysical perspective

Autor: Chorlay, Aymeric, Dhiman, Ravi, Caesar, Stefanie, Thiam, Abdou Rachid, Schrul, Bianca

Publikováno v: Seminars in Cell & Developmental Biology
Seminars in Cell & Developmental Biology, 2020, 219 (4), ⟨10.1016/j.semcdb.2020.03.004⟩

Lipid droplets (LDs), or oil bodies in plants, are specialized organelles that primarily serve as hubs of cellular metabolic energy storage and consumption. These ubiquitous cytoplasmic organelles are derived from the endoplasmic reticulum (ER) and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bd356b15be6e6ce11e08e04552adc0
https://pubmed.ncbi.nlm.nih.gov/32201131

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