Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Choongho Lee"'
Autor:
Mi Il Kim, Choongho Lee
Publikováno v:
Viruses, Vol 15, Iss 2, p 578 (2023)
The coronavirus disease 2019 (COVID-19) pandemic has had irreversible and devastating impacts on every aspect of human life. To better prepare for the next similar pandemic, a clear understanding of coronavirus biology is a prerequisite. Nevertheless
Externí odkaz:
https://doaj.org/article/59faf6b05b004d2da4060c463a394118
Autor:
Choongho Lee
Publikováno v:
Marine Drugs, Vol 18, Iss 9, p 435 (2020)
Different kinds of red algae are enriched with chemically diverse carbohydrates. In particular, a group of sulfated polysaccharides, which were isolated from the cell walls of red algae, gained a large amount of attention due to their broad-spectrum
Externí odkaz:
https://doaj.org/article/276437e8e2cd442bb3a8dcde69e1cf2f
Autor:
Choongho Lee
Publikováno v:
Marine Drugs, Vol 17, Iss 10, p 567 (2019)
Virus entry into a susceptible host cell is the first step in the formation of all viral diseases. Controlling viral infections by disrupting viral entry is advantageous for antibody-mediated neutralization by the host’s immune system and as a prev
Externí odkaz:
https://doaj.org/article/a41be1a7e9e84662a46281019e6aa9b5
Autor:
Sungjin Lee, Karabasappa Mailar, Mi Il Kim, Minkyung Park, Jiseon Kim, Dal-Hee Min, Tae-Hwe Heo, Soo Kyung Bae, Wonjun Choi, Choongho Lee
Publikováno v:
Viruses, Vol 11, Iss 10, p 890 (2019)
Oligostilbenoid compounds, a group of resveratrol multimers, display several anti-microbial activities through the neutralization of cytotoxic oxidants, and by inhibiting essential host and viral enzymes. In our previous study, we identified a series
Externí odkaz:
https://doaj.org/article/fa91da6a3a7b47c1bb0420f5512adf2e
Autor:
Choongho Lee
Publikováno v:
Molecules, Vol 24, Iss 7, p 1349 (2019)
From its unexpected discovery as a bacterial adaptive immune system to its countless applications as one of the most versatile gene-editing tools, the CRISPR/Cas9 system has revolutionized every field of life science. Virology is no exception to this
Externí odkaz:
https://doaj.org/article/fe78c154f237494783cad732a903c074
Autor:
Jae-Su Moon, Seung-Hoon Lee, Eun-Jung Kim, Hee Cho, Wooseong Lee, Geon-Woo Kim, Hyun-Ji Park, Seung-Woo Cho, Choongho Lee, Jong-Won Oh
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146710 (2016)
The hepatitis C virus (HCV) internal ribosome entry site (IRES) that directs cap-independent viral translation is a primary target for small interfering RNA (siRNA)-based HCV antiviral therapy. However, identification of potent siRNAs against HCV IRE
Externí odkaz:
https://doaj.org/article/01b432130869487b8cffc0bbcf981c90
Autor:
Dahee Kim, Ja-Il Goo, Mi Il Kim, Sung-Jin Lee, Moonju Choi, Thoa Thi Than, Phuong Hong Nguyen, Marc P. Windisch, Kyeong Lee, Yongseok Choi, Choongho Lee
Publikováno v:
Molecules, Vol 23, Iss 8, p 2083 (2018)
Diacylglycerol acyltransferases (DGATs) play a critical role in the biosynthesis of endogenous triglycerides (TGs) and formation of lipid droplets (LDs) in the liver. In particular, one member of DGATs, DGAT-1 was reported to be an essential host fac
Externí odkaz:
https://doaj.org/article/425c80447cfd4b029512346cb3d78f62
Publikováno v:
Asian Journal of Organic Chemistry. 10:2993-2999
Autor:
Dahee Kim, Thanh K. Pham, Mi Il Kim, Bi-o Kim, Minkyung Park, Choongho Lee, Young Woo Kim, You-Hee Cho
Publikováno v:
Virology. 561:6-16
Based on the previously reported 13-residue antibacterial peptide analog, brevinin-1EMa (FLGWLFKVASKVL, peptide B), we attempted to design a novel class of antiviral peptides. For this goal, we synthesized three peptides with different stapling posit
Publikováno v:
Archives of pharmacal research. 45(12)
Metabolism of carbohydrates and lipids and protein degradation occurs in the liver and contributes to the body's homeostasis by secreting a variety of mediators. Any imbalance in this homeostasis due to excess fat consumption and the pathologic event